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HAMAP annotation rule: MF_01902

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General rule information

Accession MF_01902
Dates 28-JUN-2005 (Created)
7-JUN-2008 (Last updated, Version 7)
Data class Protein
Predictors HAMAP; MF_01902; [distribution of match scores in UniProtKB];[seed alignment for MF_01902]


Propagated annotation

Identifier, protein and gene names
Identifier DNAE2
Protein name
RecName: Full=Error-prone DNA polymerase;
EC=2.7.7.7;
Gene name dnaE2
Comments
FUNCTION: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase (By similarity).
CATALYTIC ACTIVITY: Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
SUBCELLULAR LOCATION: Cytoplasm (Probable).
SIMILARITY: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
Cross-references
Pfam PF07733; DNA_pol3_alpha; 1;
PF02811; PHP; 1;
PF01336; tRNA_anti; 1;
TIGRFAMs TIGR00594; polc; 1;
Keywords
Cytoplasm, DNA damage, DNA repair, DNA replication, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase.
Gene Ontology
GO:0003887; Molecular function: DNA-directed DNA polymerase activity.
GO:0045020; Biological process: error-prone DNA repair.
GO:0005737; Cellular component: cytoplasm.


Additional information

Size range: 1024-1195 amino acids
Related UniRules: None
Template: O50399 (DNAE2_MYCTU); Q9A3J3 (DNAE2_CAUCR): [Recover all]
Scope: Bacteria; Actinobacteria
Bacteria; Planctomycetes
Bacteria; Proteobacteria
Fusion: Nter: None; Cter: None
Duplicate: in AGRT5, RHIME
Plasmid encoded: in AGRT5, GLUOX, RALSO, RHIME

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UniProtKB rule member sequences



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