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UniProtKB/Swiss-Prot entry Q9UZ57

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name IORA_PYRAB
Primary accession number Q9UZ57
Secondary accession numbers None
Integrated into Swiss-Prot on June 1, 2001
Sequence was last modified on May 1, 2000 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 53)
Name and origin of the protein
Protein name Indolepyruvate oxidoreductase subunit iorA
Synonyms IOR
EC 1.2.7.8
Indolepyruvate ferredoxin oxidoreductase subunit alpha
Gene name
Name: iorA
OrderedLocusNames: PYRAB12970
ORFNames: PAB0855
From
Pyrococcus abyssi [TaxID: 29292] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=GE5 / Orsay;
DOI=10.1046/j.1365-2958.2003.03381.x; PubMed=12622808 [NCBI, ExPASy, EBI, Israel, Japan]
Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P.;
"An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi.";
Mol. Microbiol. 47:1495-1512(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AJ248287; CAB50202.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR E75038; E75038.
RefSeq NP_126972.1; -.
3D structure databases
HSSP O28604; 1JNR. [HSSP ENTRY / PDB]
ModBase Q9UZ57.
Enzyme and pathway databases
BioCyc PABY272844:PAB0855-MON; -.
Ontologies
GO
GO:0051539; Molecular function: 4 iron, 4 sulfur cluster binding (inferred from electronic annotation from UniProtKB-KW).
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0043805; Molecular function: indolepyruvate ferredoxin oxidoreductase activity (inferred from electronic annotation from EC).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0030976; Molecular function: thiamin pyrophosphate binding (inferred from electronic annotation from InterPro).
GO:0022900; Biological process: electron transport chain (inferred from electronic annotation from UniProtKB-KW).
GO:0006810; Biological process: transport (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR001450; 4Fe4S_Fe_S_bd.
IPR017721; Indolepyruvate_Fd_OxRdtase_asu.
IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
IPR011766; TPP_enzyme_bd_C.
Graphical view of domain structure.
Pfam PF00037; Fer4; 2.
PF01855; POR_N; 1.
PF02775; TPP_enzyme_C; 1.
Pfam graphical view of domain structure.
PRINTS PR00353; 4FE4SFRDOXIN.
PROSITE PS00198; 4FE4S_FER_1; 1.
PS51379; 4FE4S_FER_2; 2.
PROSITE graphical view of domain structure (profiles).
Genome annotation databases
GeneID 1496683; -.
GenomeReviews AL096836_GR; PYRAB12970.
KEGG pab:PAB0855; -.
NMPDR fig|272844.1.peg.1376; -.
Phylogenomic databases
HOGENOM Q9UZ57; -.
Genome annotation databases
CMR Q9UZ57; PYRAB12970.
Other
ProtoNet Q9UZ57.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
4Fe-4S; Complete proteome; Electron transport; Iron; Iron-sulfur; Metal-binding; Oxidoreductase; Repeat; Transport.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   648  648     Indolepyruvate oxidoreductase subunit iorA. PRO_0000099928
DOMAIN   585   614  30     4Fe-4S ferredoxin-type 1. 
DOMAIN   616   645  30     4Fe-4S ferredoxin-type 2. 
METAL   625   625        Iron-sulfur (4Fe-4S) (Potential). 
METAL   628   628        Iron-sulfur (4Fe-4S) (Potential). 
METAL   631   631        Iron-sulfur (4Fe-4S) (Potential). 
METAL   635   635        Iron-sulfur (4Fe-4S) (Potential). 
Sequence information
Length: 648 AA [This is the length of the unprocessed precursor] Molecular weight: 71355 Da [This is the MW of the unprocessed precursor] CRC64: 069AD8E4052098F4 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MVKVTDIVLW DKPGERVLLL GNQAIVRGAL EGNIGVYAAY PGTPSSEITD TMAAVASRAG 

        70         80         90        100        110        120 
VYMEYSTNEK VAFETALSAS WAGLRAMTAM KHVGLNVAMD SFMTVSYMGV NGGLVVVVAD 

       130        140        150        160        170        180 
DPSMWSSQNE QDTRAIAKFA NIPVLEPSSV QEAKDMVKYA FEISEKYGQM VILRTTTRSS 

       190        200        210        220        230        240 
HMRGDVVLGE LPQEIKEGKR KFGDFKKNPE RYVDIPAFQR PKHKWLLETI EKFREEFNNS 

       250        260        270        280        290        300 
PFNWIEGPED AKVGIIAPGL SYAYVKEALA WLGVDNVKVL KLGTPFPVPY GLLEKFFQGL 

       310        320        330        340        350        360 
ERVLIVEELE PVVEEQVKVW AFDKGINVEI HGKDLVPRVY EMTTRRAVEA IAKFLGLETP 

       370        380        390        400        410        420 
INFEEIDEKY KKVQEIVPPR PPSLCPACPH RNTFFALRKA ATPRAIYPSD IGCYTLGVLP 

       430        440        450        460        470        480 
PLKTVDTTIA MGGSIGVAHG LSIALNGSIA EEQRKTGKGK KIIAATIGDS TFFHTGLPAL 

       490        500        510        520        530        540 
ANAIYNRSNV LIVVLDNLVT AMTGDQPNPG TGETPHGPGK RILIEEVAKA MGADFVAVVD 

       550        560        570        580        590        600 
PYDIKETYET FKKALEVEGV SVVVARRACA LYRIGQLRRA GKQWPIYQVN EDKCTGCKIC 

       610        620        630        640 
INAYGCPAIY WDPEKKKAKV DPLMCWGCGG CAQVCPFDAF EKVREGEL
Q9UZ57 in FASTA format

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