NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=IL1403;
DOI=10.1101/gr.GR-1697R; PubMed=11337471 [NCBI, ExPASy, EBI, Israel, Japan]
Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J., Ehrlich S.D., Sorokin A.;
"The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403.";
Genome Res. 11:731-753(2001).

Comments

CATALYTIC ACTIVITY: N⁵-(L-1-carboxyethyl)-L-ornithine + NADP⁺ + H₂O = L-ornithine + pyruvate + NADPH.
SUBUNIT: Homotetramer (By similarity).
MISCELLANEOUS: In the reverse direction L-lysine can act instead of L-ornithine, more slowly, yielding N(6)-(L-1-carboxyethyl)-L-lysine (By similarity).

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AE006356; AAK05335.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

E86779; E86779.

RefSeq

NP_267393.1; -.

3D structure databases

ModBase

Q9CG73.

Enzyme and pathway databases

BioCyc

LLAC272623:L64332-MON; -.

Ontologies

GO:0005488;	Molecular function: binding (inferred from electronic annotation from InterPro).
GO:0009055;	Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0047126;	Molecular function: N5-(carboxyethyl)ornithine synthase activity (inferred from electronic annotation from EC).
GO:0055114;	Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

InterPro

IPR007698; Ala_DHase/PNT_C.
IPR007886; Ala_DHase/PNT_N.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.720; NAD(P)-bd; 1.

Pfam

PF01262; AlaDh_PNT_C; 1.
PF05222; AlaDh_PNT_N; 1.
Pfam graphical view of domain structure.

Genome annotation databases

1114886; -.

AE005176_GR; LL1237.

lla:L64332; -.

fig|272623.1.peg.1272; -.

Phylogenomic databases

HOGENOM

Q9CG73; -.

Genome annotation databases

CMR

Q9CG73; LL1237.

Other

ProtoNet

Q9CG73.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; NADP; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 309`	`309`	`N(5)-(carboxyethyl)ornithine synthase.`	`PRO_0000089482`
`NP_BIND`	`171 176`	`6`	`NADP (Potential).`

Sequence information

Length: 309 AA [This is the length of the unprocessed precursor]

Molecular weight: 35008 Da [This is the MW of the unprocessed precursor]

CRC64: 51C5E5ED8DE508FA [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKIGLVKTNF PGERRVPLLP KDIKDFKNEI LVEEGFGKFL DIDDQEYIDK GCHILSRAEV 

        70         80         90        100        110        120 
FSESEAIFSL KLIQPTDYPY LREGQMIIGW THPFGSGRLF MKEQALPKKL IVVDLDSNSP 

       130        140        150        160        170        180 
CIYYENEIFE SGIPKGLLYK NSFYAGYAGV LDALLQYGFI PTEETKIAIL GSGNVAQGAF 

       190        200        210        220        230        240 
SSISKYSSNI RMYYRKTMSI FKENYTKYDI IINGIEIGKE DDPILSFSEQ KSLKKGTFII 

       250        260        270        280        290        300 
DVAADAGNTI EGTHFTSMDD PIYENDGKYY YVVPNTPSLI YRNVSQDLSK ILSENIFSED 


CSRFLSIKS

Q9CG73 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools