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UniProtKB/Swiss-Prot entry Q8UDV0


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ILVC_AGRT5
Primary accession number Q8UDV0
Secondary accession numbers None
Integrated into Swiss-Prot on June 6, 2003
Sequence was last modified on June 1, 2002 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 40)
Name and origin of the protein
Protein name Ketol-acid reductoisomerase
Synonyms EC 1.1.1.86
Acetohydroxy-acid isomeroreductase
Alpha-keto-beta-hydroxylacil reductoisomerase
Gene name
Name: ilvC
OrderedLocusNames: Atu2019
ORFNames: AGR_C_3660
From
Agrobacterium tumefaciens (strain C58 / ATCC 33970) [TaxID: 176299] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1066804; PubMed=11743193 [NCBI, ExPASy, EBI, Israel, Japan]
Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K., Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y., Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P., Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R., Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G., Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y., Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S., Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F., Gordon M.P., Olson M.V., Nester E.W.;
"The genome of the natural genetic engineer Agrobacterium tumefaciens C58.";
Science 294:2317-2323(2001).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1066803; PubMed=11743194 [NCBI, ExPASy, EBI, Israel, Japan]
Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B., Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K., Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M., Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C., Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
"Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58.";
Science 294:2323-2328(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE007869; AAK87773.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR AE2824; AE2824.
D97602; D97602.
RefSeq NP_354988.1; -.
3D structure databases
HSSP Q9HVA2; 1NP3. [HSSP ENTRY / PDB]
ModBase Q8UDV0.
Ontologies
GO
GO:0005488; Molecular function: binding (inferred from electronic annotation from InterPro).
GO:0004455; Molecular function: ketol-acid reductoisomerase activity (inferred from electronic annotation from HAMAP).
GO:0009097; Biological process: isoleucine biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0009099; Biological process: valine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00435; -; 1.
PBIL [Tree]
InterPro IPR013023; AcH_isomrdctse.
IPR000506; AcH_isomrdctse_C.
IPR013116; IlvN.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR21371; AcH_isomrdctse; 1.
Pfam PF01450; IlvC; 1.
PF07991; IlvN; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00465; ilvC; 1.
ProtoNet Q8UDV0.
Genome annotation databases
GeneID 1134057; -.
GenomeReviews AE007869_GR; Atu2019.
KEGG atc:AGR_C_3660; -.
atu:Atu2019; -.
Phylogenomic databases
HOGENOM Q8UDV0; -.
Genome annotation databases
CMR Q8UDV0; Atu2019.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   339  339     Ketol-acid reductoisomerase. PRO_0000151267
ACT_SITE   108   108        Potential. 
Sequence information
Length: 339 AA [This is the length of the unprocessed precursor] Molecular weight: 36710 Da [This is the MW of the unprocessed precursor] CRC64: D14D2284BAE8F6AA [This is a checksum on the sequence]
        10         20         30         40         50         60 
MRVYYDRDAD LNLIKSKNVV IVGYGSQGRA HALNLKDSGA KNVVIALKAG SPTVKKAEAD 

        70         80         90        100        110        120 
GFKVMTVAEA AKWGDLLMMA TPDELQADIY KADIAGNIRD GAAIAFAHGL NVHFGLIEPK 

       130        140        150        160        170        180 
ASLDVVMIAP KGPGHTVRGE YQKGGGVPCL VAVHHNASGN ALELALSYAC GVGGGRSGII 

       190        200        210        220        230        240 
ETNFKEECET DLFGEQVVLC GGLVELIRAG FETLTEAGYA PEMAYFECLH EVKLIVDLIY 

       250        260        270        280        290        300 
EGGIANMNYS ISNTAEWGEY VTGPRIITAE TKAEMKRVLH DIQTGKFTSD WMQEYRSGAA 

       310        320        330 
RFKGIRRMND THQIEEVGAK LRGMMPWIGK NKLVDKAVN 

Q8UDV0 in FASTA format

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