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UniProtKB/Swiss-Prot entry Q86IV5


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CTNA_DICDI
Primary accession number Q86IV5
Secondary accession numbers Q556C3 Q9U7C4
Integrated into Swiss-Prot on April 8, 2008
Sequence was last modified on June 1, 2003 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 24)
Name and origin of the protein
Protein name Countin-1 [Precursor]
Synonyms None
Gene name
Name: ctnA
ORFNames: DDB_0185089
From
Dictyostelium discoideum (Slime mold) [TaxID: 44689] 
Taxonomy Eukaryota; Mycetozoa; Dictyosteliida; Dictyostelium.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 22-41, IDENTIFICATION IN THE COUNTIN COMPLEX, DEVELOPMENTAL STAGE, SUBCELLULAR LOCATION, FUNCTION, AND KNOCKOUT.
PubMed=10444594 [NCBI, ExPASy, EBI, Israel, Japan]
Brock D.A., Gomer R.H.;
"A cell-counting factor regulating structure size in Dictyostelium.";
Genes Dev. 13:1960-1969(1999).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AX4;
DOI=10.1038/nature00847; PubMed=12097910 [NCBI, ExPASy, EBI, Israel, Japan]
Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T., Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R., Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A., Noegel A.A.;
"Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
Nature 418:79-85(2002).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AX4;
DOI=10.1038/nature03481; PubMed=15875012 [NCBI, ExPASy, EBI, Israel, Japan]
Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
"The genome of the social amoeba Dictyostelium discoideum.";
Nature 435:43-57(2005).
[4]
FUNCTION.
DOI=10.1016/S1097-2765(00)00093-9; PubMed=11090633 [NCBI, ExPASy, EBI, Israel, Japan]
Roisin-Bouffay C., Jang W., Caprette D.R., Gomer R.H.;
"A precise group size in Dictyostelium is generated by a cell-counting factor modulating cell-cell adhesion.";
Mol. Cell 6:953-959(2000).
[5]
FUNCTION, AND DEVELOPMENTAL STAGE.
DOI=10.1046/j.1440-169X.2001.00615.x; PubMed=11737154 [NCBI, ExPASy, EBI, Israel, Japan]
Okuwa T., Katayama T., Takano A., Kodaira K., Yasukawa H.;
"Two cell-counting factors regulate the aggregate size of the cellular slime mold Dictyostelium discoideum.";
Dev. Growth Differ. 43:735-744(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AF140780; AAD53482.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AC116986; AAO51901.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AAFI02000012; EAL70191.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_643887.1; -.
3D structure databases
ModBase Q86IV5.
Organism-specific databases
dictyBase DDB0185089; ctnA.
Family and domain databases
InterPro IPR008139; SaposinB.
Graphical view of domain structure.
SMART SM00741; SapB; 1.
SMART graphical view of domain structure.
PROSITE PS50015; SAP_B; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q86IV5.
Genome annotation databases
GeneID 3395201; -.
KEGG ddi:DDB_0185089; -.
Other
ProtoNet Q86IV5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Direct protein sequencing; Glycoprotein; Secreted; Signal.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
SIGNAL   1    21  21      
CHAIN   22   258  237     Countin-1. PRO_0000327908
DOMAIN   22   106  85     Saposin B-type. 
CARBOHYD   121   121        N-linked (GlcNAc...) (Potential). 
CARBOHYD   215   215        N-linked (GlcNAc...) (Potential). 
DISULFID   25   102        By similarity. 
DISULFID   28    96        By similarity. 
DISULFID   56    69        By similarity. 
CONFLICT   45    45        Missing (in Ref. 1; AAD53482). 
Sequence information
Length: 258 AA [This is the length of the unprocessed precursor] Molecular weight: 26659 Da [This is the MW of the unprocessed precursor] CRC64: 725F37870E78356A [This is a checksum on the sequence]
        10         20         30         40         50         60 
MNKLFSLILA LFLVNSAVVS SLDSCSICVD FVGNSLNDLL NIILNSGVIG TCGDLCSAVP 

        70         80         90        100        110        120 
GGQIVDTVCD LLCDYVGVDE FIKLISDVDP DPIYICEKIS VCKTNDNAAA SLDLVQINPQ 

       130        140        150        160        170        180 
NGTVGGTFTL SIAYTVTNTI ATGQLAFNII DPTGNAFGDA VLLVQQSPEQ YTQQFQFQAT 

       190        200        210        220        230        240 
PSEQESFPNG LYTVQALVCE GSCGSPHPNT YTLANGTTTF TISGADSSSM SGAGSFSGSS 

       250 
QSTQTGAASG SGSGFALF 

Q86IV5 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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