NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Prostate;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).

Comments

FUNCTION: May play a role in intracellular membrane fusion (By similarity).
SUBUNIT: Forms a complex containing SNAP47, VAMP2 and STX1A (By similarity).
SUBCELLULAR LOCATION: Endomembrane system (By similarity). Cytoplasm, perinuclear region (By similarity). Note=Appears to be exclusively membrane-bound (By similarity).
SIMILARITY: Belongs to the SVAP1 family.
SIMILARITY: Contains 2 t-SNARE coiled-coil homology domains.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

BC062056; AAH62056.1; -; mRNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

IPI00369583; -.

NP_955421.1; -.

3D structure databases

ModBase

Q6P6S0.

PTM databases

PhosphoSite

Q6P6S0; -.

Organism-specific databases

RGD

735194; RGD735194.

Ontologies

GO:0012505;	Cellular component: endomembrane system (inferred from electronic annotation from UniProtKB-SubCell).
GO:0016020;	Cellular component: membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0048471;	Cellular component: perinuclear region of cytoplasm (inferred from electronic annotation from UniProtKB-SubCell).
QuickGo view.

Family and domain databases

InterPro

IPR000727; T_SNARE.
Graphical view of domain structure.

PROSITE

PS50192; T_SNARE; 2.
PROSITE graphical view of domain structure (profiles).

Proteomic databases

PRIDE

Q6P6S0; -.

Genome annotation databases

Ensembl

ENSRNOG00000022472; Rattus norvegicus. [Contig view]

GeneID

303183; -.

KEGG

rno:303183; -.

NMPDR

fig|10116.3.peg.5136; -.

Phylogenomic databases

HOVERGEN

Q6P6S0; -.

OMA

Q6P6S0; PSRNVVF.

Other

650811; -.

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Coiled coil; Cytoplasm; Membrane; Repeat.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 419`	`419`	`Synaptosomal-associated protein 47.`	`PRO_0000307153`
`DOMAIN`	`109 171`	`63`	`t-SNARE coiled-coil homology 1.`
`DOMAIN`	`356 418`	`63`	`t-SNARE coiled-coil homology 2.`

Sequence information

Length: 419 AA [This is the length of the unprocessed precursor]

Molecular weight: 47042 Da [This is the MW of the unprocessed precursor]

CRC64: 4B7D9E4E9A448D0F [This is a checksum on the sequence]

        10         20         30         40         50         60 
MSSDVRVHTW PCSYYLDLEK QWLPGKLTLT PRSLKFSVDK AEEVLVGLPL SSITEIRKET 

        70         80         90        100        110        120 
SLFIFSAITV LEKGQAKHWF SSLRPSRNVV FNIIEHFWRE LLLSQPGTAA NPTSPMTRGQ 

       130        140        150        160        170        180 
ELMGLMASSQ RRMEDTAKVL HHQGEQLDSV MRGLEKMESD LDVADRLLTE LETPSWWPFS 

       190        200        210        220        230        240 
AKFWKTPVEA KPRDSVSVAP CEPFGKEGVV IRVPAVVSQR TESHSKPGKL TVLVSGLEIH 

       250        260        270        280        290        300 
DSSSLLLHRF EKEDVDDIKV HSPYEVSIRQ RFIGKPDVAY RLISAKMPEV IPILEVQFSK 

       310        320        330        340        350        360 
KIELLEDALV LRSRGRASPA EGGCSIRHAA SRLMGCTTHQ ELPTGGQEGQ QSQLQKDWPL 

       370        380        390        400        410 
LSEGEAQELT QILSKLKGLA LDTEAELERQ DAALDGITVA VDRATLTVDK HNRRMRKLL

Q6P6S0 in FASTA format

View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools