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UniProtKB/Swiss-Prot entry Q6NFM3

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name COX1_CORDI
Primary accession number Q6NFM3
Secondary accession numbers None
Integrated into Swiss-Prot on April 26, 2005
Sequence was last modified on July 5, 2004 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 34)
Name and origin of the protein
Protein name Cytochrome c oxidase subunit 1
Synonyms EC 1.9.3.1
Cytochrome c oxidase polypeptide I
Cytochrome aa3 subunit 1
Gene name
Name: ctaD
OrderedLocusNames: DIP1864
From
Corynebacterium diphtheriae [TaxID: 1717] [HAMAP proteome]
Taxonomy Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Corynebacterineae; Corynebacteriaceae; Corynebacterium.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 700971 / NCTC 13129 / Biotype gravis;
DOI=10.1093/nar/gkg874; PubMed=14602910 [NCBI, ExPASy, EBI, Israel, Japan]
Cerdeno-Tarraga A.-M., Efstratiou A., Dover L.G., Holden M.T.G., Pallen M.J., Bentley S.D., Besra G.S., Churcher C.M., James K.D., De Zoysa A., Chillingworth T., Cronin A., Dowd L., Feltwell T., Hamlin N., Holroyd S., Jagels K., Moule S., Quail M.A., Rabbinowitsch E., Rutherford K.M., Thomson N.R., Unwin L., Whitehead S., Barrell B.G., Parkhill J.;
"The complete genome sequence and analysis of Corynebacterium diphtheriae NCTC13129.";
Nucleic Acids Res. 31:6516-6523(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BX248359; CAE50393.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_940201.1; -.
3D structure databases
ModBase Q6NFM3.
Enzyme and pathway databases
BioCyc CDIP257309:DIP1864-MON; -.
Ontologies
GO
GO:0016021; Cellular component: integral to membrane (inferred from electronic annotation from InterPro).
GO:0005746; Cellular component: mitochondrial respiratory chain (inferred from electronic annotation from UniProtKB-KW).
GO:0005886; Cellular component: plasma membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0005507; Molecular function: copper ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0004129; Molecular function: cytochrome-c oxidase activity (inferred from electronic annotation from InterPro).
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0020037; Molecular function: heme binding (inferred from electronic annotation from InterPro).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from InterPro).
GO:0009060; Biological process: aerobic respiration (inferred from electronic annotation from InterPro).
GO:0022900; Biological process: electron transport chain (inferred from electronic annotation from UniProtKB-KW).
GO:0006810; Biological process: transport (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR000883; COX1.
IPR014241; COX1_bac-type.
Graphical view of domain structure.
Gene3D G3DSA:1.20.210.10; COX1; 1.
PANTHER PTHR10422; COX1; 1.
Pfam PF00115; COX1; 1.
Pfam graphical view of domain structure.
PRINTS PR01165; CYCOXIDASEI.
TIGRFAMs TIGR02891; CtaD_CoxA; 1.
PROSITE PS50855; COX1; 1.
PS00077; COX1_CUB; 1.
PROSITE graphical view of domain structure (profiles).
Genome annotation databases
GeneID 2649239; -.
GenomeReviews BX248353_GR; DIP1864.
KEGG cdi:DIP1864; -.
NMPDR fig|257309.1.peg.1792; -.
Phylogenomic databases
HOGENOM Q6NFM3; -.
Genome annotation databases
CMR Q6NFM3; DIP1864.
Other
ProtoNet Q6NFM3.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cell membrane; Complete proteome; Copper; Electron transport; Heme; Iron; Membrane; Metal-binding; Oxidoreductase; Respiratory chain; Transmembrane; Transport.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   564  564     Cytochrome c oxidase subunit 1. PRO_0000183438
TRANSMEM   43    63  21     Potential. 
TRANSMEM   83   103  21     Potential. 
TRANSMEM   122   142  21     Potential. 
TRANSMEM   171   191  21     Potential. 
TRANSMEM   214   234  21     Potential. 
TRANSMEM   259   279  21     Potential. 
TRANSMEM   292   312  21     Potential. 
TRANSMEM   316   336  21     Potential. 
TRANSMEM   360   380  21     Potential. 
TRANSMEM   399   419  21     Potential. 
TRANSMEM   434   454  21     Potential. 
TRANSMEM   477   497  21     Potential. 
METAL   87    87        Iron (heme A axial ligand) (Probable). 
METAL   265   265        Copper B (Probable). 
METAL   269   269        Copper B (Probable). 
METAL   314   314        Copper B (Probable). 
METAL   315   315        Copper B (Probable). 
METAL   398   398        Iron (heme A3 axial ligand) (Probable). 
METAL   400   400        Iron (heme A axial ligand) (Probable). 
CROSSLNK   265   269        1'-histidyl-3'-tyrosine (His-Tyr) (By similarity). 
Sequence information
Length: 564 AA [This is the length of the unprocessed precursor] Molecular weight: 63291 Da [This is the MW of the unprocessed precursor] CRC64: 2865A8DB72B3CA6E [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTAVAPRLEN YAEPTRPAPT GGARKGTLAW KMLTTTDHKL LGMMYIVMSF VWFFVGGLMA 

        70         80         90        100        110        120 
LLIRAELFSP GLQFLSNEQF NQLFTLHGTI MLLAFGTPVV WGFSNYILPL QIGAPDVAFP 

       130        140        150        160        170        180 
RLNAFGFWIT QIGVVAMLAG FLTPGGAADF GWTMYLPLAD SIHSPGVGGD FWIIGVGATG 

       190        200        210        220        230        240 
VGTIASAVNM ITTILCMRAP GMTMFRMPIF CWNIFVASVI VLLIFPLLTA AALGVMYDRK 

       250        260        270        280        290        300 
LGGHIYDPGN GGAILWQHLF WFFGHPEVYV LALPFFGIVS EVIPVFARKP MFGYIGLVFA 

       310        320        330        340        350        360 
TLSIGMLSMA VWAHHMFVTG AILLPFFSFM TFLISVPTGV KFFNWLGTMW RGHISWETPM 

       370        380        390        400        410        420 
TWTMGFLVTF LFGGLTGIML ASPPLDFHIS DTYFVVAHFH YTLFGTVVFA SYAGVYFWFP 

       430        440        450        460        470        480 
KMTGRMLDER LGKIHFWITF VGFHGTFLVQ HWVGNEGMPR RYADYLESDG FTTLNQISTV 

       490        500        510        520        530        540 
FSFLLGVSVI PFIWNVFKSY RYGEIVTVDD PWGYGNSLEW ATSCPPPRHN FTSLPRIRSE 

       550        560 
RPAFELHYPH MVERMRREAH IGHH
Q6NFM3 in FASTA format

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