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UniProtKB/Swiss-Prot entry Q63XA4


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name QUEF_BURPS
Primary accession number Q63XA4
Secondary accession numbers None
Integrated into Swiss-Prot on November 22, 2005
Sequence was last modified on October 25, 2004 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 33)
Name and origin of the protein
Protein name NADPH-dependent 7-cyano-7-deazaguanine reductase
Synonyms EC 1.7.1.13
7-cyano-7-carbaguanine reductase
PreQ(0) reductase
NADPH-dependent nitrile oxidoreductase
Gene name
Name: queF
OrderedLocusNames: BPSL0632
From
Burkholderia pseudomallei (Pseudomonas pseudomallei) [TaxID: 28450] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Burkholderiaceae; Burkholderia; pseudomallei group.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K96243;
DOI=10.1073/pnas.0403302101; PubMed=15377794 [NCBI, ExPASy, EBI, Israel, Japan]
Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.-M., Atkins T., Crossman L.C., Pitt T., Churcher C., Mungall K.L., Bentley S.D., Sebaihia M., Thomson N.R., Bason N., Beacham I.R., Brooks K., Brown K.A., Brown N.F., Challis G.L., Cherevach I., Chillingworth T., Cronin A., Crossett B., Davis P., DeShazer D., Feltwell T., Fraser A., Hance Z., Hauser H., Holroyd S., Jagels K., Keith K.E., Maddison M., Moule S., Price C., Quail M.A., Rabbinowitsch E., Rutherford K., Sanders M., Simmonds M., Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M., Whitehead S., Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J.;
"Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei.";
Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BX571965; CAH34625.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_107261.1; -.
3D structure databases
ModBase Q63XA4.
Enzyme and pathway databases
BioCyc BPSE272560:BPSL0632-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0046857; Molecular function: oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor (inferred from electronic annotation from HAMAP).
GO:0033739; Molecular function: queuine synthase activity (inferred from electronic annotation from EC).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0008616; Biological process: queuosine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00817; -; 1.
PBIL [Tree]
InterPro IPR016428; CN_OxRdtase_NADPH-dep_YqcD.
IPR001474; GTP_CycOHase_I.
Graphical view of domain structure.
Pfam PF01227; GTP_cyclohydroI; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF004750; Nitrile_oxidored_YqcD_prd; 1.
TIGRFAMs TIGR03138; QueF; 1.
BLOCKS Q63XA4.
ProtoNet Q63XA4.
Genome annotation databases
GeneID 3092289; -.
GenomeReviews BX571965_GR; BPSL0632.
KEGG bps:BPSL0632; -.
Phylogenomic databases
HOGENOM Q63XA4; -.
Genome annotation databases
CMR Q63XA4; BPSL0632.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; NADP; Oxidoreductase; Queuosine biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   274  274     NADPH-dependent 7-cyano-7-deazaguanine reductase. PRO_0000163025
Sequence information
Length: 274 AA [This is the length of the unprocessed precursor] Molecular weight: 30401 Da [This is the MW of the unprocessed precursor] CRC64: 6725ED3BAE432F9F [This is a checksum on the sequence]
        10         20         30         40         50         60 
MNPEHSPLGK ATVYANQYDA SLLFPIPRAG AREQIGIGAP LPFFGTDIWN AYELSWLNAR 

        70         80         90        100        110        120 
GKPQIAIATF YVPAESPNIV ESKSFKLYLG SFAQTAFESA DAVRDALKRD VSAACDASVT 

       130        140        150        160        170        180 
VRLATPAEFR KLQMDELDGL SLDRLDLDAH VYETDPSFLT ASHGEAPVEE TLVTDLLKSN 

       190        200        210        220        230        240 
CPVTGQPDWG SVQIHYVGAP IDHAGLLRYI ISFRNHTGFH EQCVERIFVD ILRACQPVKL 

       250        260        270 
AVYARYTRRG GLDINPFRTN YNQPMPDNAR TARQ 

Q63XA4 in FASTA format

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