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UniProtKB/Swiss-Prot entry Q5P6Y5

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PYRC_AZOSE
Primary accession number Q5P6Y5
Secondary accession numbers None
Integrated into Swiss-Prot on March 18, 2008
Sequence was last modified on January 4, 2005 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 27)
Name and origin of the protein
Protein name Dihydroorotase
Synonyms DHOase
EC 3.5.2.3
Gene name
Name: pyrC
OrderedLocusNames: AZOSEA08010
ORFNames: ebA1456
From
Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) [TaxID: 76114] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Rhodocyclales; Rhodocyclaceae; Aromatoleum.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1007/s00203-004-0742-9; PubMed=15551059 [NCBI, ExPASy, EBI, Israel, Japan]
Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F., Reinhardt R.;
"The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1.";
Arch. Microbiol. 183:27-36(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CR555306; CAI06926.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_157827.1; -.
3D structure databases
ModBase Q5P6Y5.
Enzyme and pathway databases
BioCyc ASP76114:EBA1456-MON; -.
Ontologies
GO
GO:0004151; Molecular function: dihydroorotase activity (inferred from electronic annotation from HAMAP).
GO:0008270; Molecular function: zinc ion binding (inferred from electronic annotation from HAMAP).
GO:0019856; Biological process: pyrimidine base biosynthetic process (inferred from electronic annotation from InterPro).
GO:0006221; Biological process: pyrimidine nucleotide biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00219; -; 1.
PBIL [Tree]
InterPro IPR006680; Amidohydro_1.
IPR004721; DHOdimr.
IPR002195; Dihydroorotase_CS.
Graphical view of domain structure.
Pfam PF01979; Amidohydro_1; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF001237; DHOdimr; 1.
TIGRFAMs TIGR00856; pyrC_dimer; 1.
PROSITE PS00482; DIHYDROOROTASE_1; 1.
PS00483; DIHYDROOROTASE_2; 1.
Genome annotation databases
GeneID 3181227; -.
GenomeReviews CR555306_GR; AZOSEA08010.
KEGG eba:ebA1456; -.
NMPDR fig|76114.4.peg.353; -.
Phylogenomic databases
HOGENOM Q5P6Y5; -.
Genome annotation databases
CMR Q5P6Y5; AZOSEA08010.
Other
ProtoNet Q5P6Y5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Hydrolase; Metal-binding; Pyrimidine biosynthesis; Zinc.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   344  344     Dihydroorotase. PRO_0000325570
METAL   13    13        Zinc 1 (By similarity). 
METAL   15    15        Zinc 1 (By similarity). 
METAL   99    99        Zinc 1; via carbamate group (By similarity). 
METAL   99    99        Zinc 2; via carbamate group (By similarity). 
METAL   136   136        Zinc 2 (By similarity). 
METAL   174   174        Zinc 2 (By similarity). 
METAL   247   247        Zinc 1 (By similarity). 
MOD_RES   99    99        N6-carboxylysine (By similarity). 
Sequence information
Length: 344 AA [This is the length of the unprocessed precursor] Molecular weight: 37310 Da [This is the MW of the unprocessed precursor] CRC64: 75E74BD36B3B7FC3 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MQTISLIRPD DWHLHVRDGA ALATVVPHTA RRFGRALIMP NLRPPVTTAA QALEYRARIL 

        70         80         90        100        110        120 
AAVPPGQHFE PLMSLYLTDN TSPDEIDRAK ASGAVVAVKL YPAGATTNSD AGVTAIEKVH 

       130        140        150        160        170        180 
AVLERMEKLG MVLCVHGEVT HGDVDVFDRE QVFIEQVLAP LVARFPALRV VFEHITTAEA 

       190        200        210        220        230        240 
ARFVQDAGPN VAATVTAHHL LLNRNAIFAG GIRPHHYCLP VLKRETHRRA LVEAATSGNA 

       250        260        270        280        290        300 
KFFLGTDSAP HSRAAKETAC GCAGCYTAHA AIELYAEAFE QAGALDRLEA FASLNGPAFY 

       310        320        330        340 
GLAPNAERIT LAKDAWEVPG EYEYLHDDPL VPLRAGETVA WRVL
Q5P6Y5 in FASTA format

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