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UniProtKB/Swiss-Prot entry Q58138

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name COOS_METJA
Primary accession number Q58138
Secondary accession numbers None
Integrated into Swiss-Prot on October 31, 2003
Sequence was last modified on June 1, 1998 (Sequence version 2)
Annotations were last modified on    November 25, 2008 (Entry version 50)
Name and origin of the protein
Protein name Carbon monoxide dehydrogenase
Synonyms CODH
EC 1.2.99.2
Gene name
Name: cooS
OrderedLocusNames: MJ0728
From
Methanocaldococcus jannaschii (Methanococcus jannaschii) [TaxID: 2190] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Methanococci; Methanococcales; Methanocaldococcaceae; Methanocaldococcus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
PubMed=8688087 [NCBI, ExPASy, EBI, Israel, Japan]
Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R., Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L., Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R., Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D., Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P., Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
"Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii.";
Science 273:1058-1073(1996).
[2]
 REVIEW.
DOI=10.1021/bi015932+; PubMed=11841199 [NCBI, ExPASy, EBI, Israel, Japan]
Lindahl P.A.;
"The Ni-containing carbon monoxide dehydrogenase family: light at the end of the tunnel?";
Biochemistry 41:2097-2105(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
L77117; AAB98724.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR H64390; H64390.
RefSeq NP_247713.1; -.
3D structure databases
HSSP Q9F8A8; 1JJY. [HSSP ENTRY / PDB]
ModBase Q58138.
Enzyme and pathway databases
BioCyc MJAN243232:MJ_0728-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from InterPro).
GO:0051539; Molecular function: 4 iron, 4 sulfur cluster binding (inferred from electronic annotation from InterPro).
GO:0018492; Molecular function: carbon-monoxide dehydrogenase (acceptor) activity (inferred from electronic annotation from InterPro).
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0016151; Molecular function: nickel ion binding (inferred from electronic annotation from InterPro).
GO:0006091; Biological process: generation of precursor metabolites and energy (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR016101; CO_DHase_a-bundle.
IPR010047; CO_DHase_cat.
IPR004137; Prismane.
IPR016099; Prismane-like_a/b-sand.
Graphical view of domain structure.
Gene3D G3DSA:1.20.1270.30; CO_DH_a-bundle; 1.
G3DSA:3.40.50.2030; Prismane-like_a/b-sand; 1.
Pfam PF03063; Prismane; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF005023; CODH; 1.
TIGRFAMs TIGR01702; CO_DH_cata; 1.
ProtoNet Q58138.
Genome annotation databases
GeneID 1451605; -.
GenomeReviews L77117_GR; MJ0728.
KEGG mja:MJ0728; -.
NMPDR fig|243232.1.peg.750; -.
TIGR MJ0728; -.
Phylogenomic databases
HOGENOM Q58138; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
4Fe-4S; Complete proteome; Iron; Iron-sulfur; Metal-binding; Nickel; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   624  624     Carbon monoxide dehydrogenase. PRO_0000157143
METAL   37    37        Iron-sulfur 1 (4Fe-4S); shared with dimeric partner (By similarity). 
METAL   46    46        Iron-sulfur 2 (4Fe-4S) (By similarity). 
METAL   49    49        Iron-sulfur 2 (4Fe-4S) (By similarity). 
METAL   54    54        Iron-sulfur 2 (4Fe-4S) (By similarity). 
METAL   65    65        Iron-sulfur 2 (4Fe-4S) (By similarity). 
METAL   256   256        Nickel-iron-sulfur (By similarity). 
METAL   292   292        Nickel-iron-sulfur (By similarity). 
METAL   336   336        Nickel-iron-sulfur (By similarity). 
METAL   444   444        Nickel-iron-sulfur (By similarity). 
METAL   475   475        Nickel-iron-sulfur (By similarity). 
METAL   516   516        Nickel-iron-sulfur (By similarity). 
Sequence information
Length: 624 AA [This is the length of the unprocessed precursor] Molecular weight: 67408 Da [This is the MW of the unprocessed precursor] CRC64: FFB6AA3376D1050E [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MKNCIAAIPE VKEMVEKAKL KGIETPHTRF PNQFPKCPYG LKGVYCILCA NGPCRITEKT 

        70         80         90        100        110        120 
PYGVCGATAD VIVARNLCRA VAAGTSCYVH CAENAARALL SAGKGEGSYE IRNEKKLKFL 

       130        140        150        160        170        180 
AKKLGFDANK DAKQLAVEVA EFILDDMYKP RWEKSELVPK LCPEKRLEVF EKLDILPGGA 

       190        200        210        220        230        240 
KGEIVDALTK TSTNLNSNPM DLLVHCLRLG LHAGFTGLLM TCWLNDILFG SPKITVVENG 

       250        260        270        280        290        300 
FSSVKPNNVN IMITGHQHAL IQPLCEAAME EDLIKMAKEA GADEIKIIGA TCNGQDMETR 

       310        320        330        340        350        360 
IAHLPESFVG YIANNFTTEP LVATGLIDAV VSEFNCTFHG LKFVAEKTKT KLICIDDMAY 

       370        380        390        400        410        420 
VEGAEYIPWE PENAKEKARE IIKKAIEAFK ERKGMQKDYY DEKVKSVVGV GEESLVEFLG 

       430        440        450        460        470        480 
GSVKPLIELI ASGKIKGVVG VVGCSNLASG GHDNIIVTLT KELIKRDILV LAGGCVNSPL 

       490        500        510        520        530        540 
KHAGLFDPAS AELAGENLKE VCKSLGIPPV LNFGACLSIA RIEQVAVAIA EELGVDIPDL 

       550        560        570        580        590        600 
PVAASAPQWL EEQALADATY AVDMGFTVHV SPVPFVTGSE LVTKVLTEAV EGLTGGKLIP 

       610        620 
EPNPYKAADL LEQTIMEKRK KLGI
Q58138 in FASTA format

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