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UniProtKB/Swiss-Prot entry Q54RK5

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ENOA_DICDI
Primary accession number Q54RK5
Secondary accession numbers None
Integrated into Swiss-Prot on April 29, 2008
Sequence was last modified on May 24, 2005 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 26)
Name and origin of the protein
Protein name Enolase A
Synonyms EC 4.2.1.11
2-phosphoglycerate dehydratase A
2-phospho-D-glycerate hydro-lyase A
Gene name
Name: enoA
ORFNames: DDB_G0283137
From
Dictyostelium discoideum (Slime mold) [TaxID: 44689] 
Taxonomy Eukaryota; Amoebozoa; Mycetozoa; Dictyosteliida; Dictyostelium.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AX4;
DOI=10.1038/nature03481; PubMed=15875012 [NCBI, ExPASy, EBI, Israel, Japan]
Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
"The genome of the social amoeba Dictyostelium discoideum.";
Nature 435:43-57(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AAFI02000050; EAL65898.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_639231.1; -.
3D structure databases
SMR Q54RK5; 4-432.
ModBase Q54RK5.
Organism-specific databases
dictyBase DDB_G0283137; enoA.
Ontologies
GO
GO:0000015; Cellular component: phosphopyruvate hydratase complex (inferred from electronic annotation from InterPro).
GO:0000287; Molecular function: magnesium ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0004634; Molecular function: phosphopyruvate hydratase activity (inferred from electronic annotation from InterPro).
GO:0006096; Biological process: glycolysis (inferred from electronic annotation from InterPro).
GO:0019953; Biological process: sexual reproduction (inferred from expression pattern from dictyBase).
QuickGo view.
Family and domain databases
InterPro IPR000941; Enolase.
Graphical view of domain structure.
PANTHER PTHR11902; Enolase; 1.
Pfam PF00113; Enolase_C; 1.
PF03952; Enolase_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF001400; Enolase; 1.
PRINTS PR00148; ENOLASE.
ProDom PD000902; Enolase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR01060; eno; 1.
PROSITE PS00164; ENOLASE; 1.
ProtoNet Q54RK5.
Genome annotation databases
GeneID 3390815; -.
KEGG ddi:DDB_0231355; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Glycolysis; Lyase; Magnesium; Metal-binding.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   434  434     Enolase A. PRO_0000330350
REGION   373   376  4     Substrate binding (By similarity). 
ACT_SITE   212   212        Proton donor (By similarity). 
ACT_SITE   346   346        Proton acceptor (By similarity). 
METAL   247   247        Magnesium (By similarity). 
METAL   296   296        Magnesium (By similarity). 
METAL   321   321        Magnesium (By similarity). 
BINDING   160   160        Substrate (By similarity). 
BINDING   169   169        Substrate (By similarity). 
BINDING   296   296        Substrate (By similarity). 
BINDING   321   321        Substrate (By similarity). 
BINDING   397   397        Substrate (By similarity). 
Sequence information
Length: 434 AA [This is the length of the unprocessed precursor] Molecular weight: 46991 Da [This is the MW of the unprocessed precursor] CRC64: 9AA4156D859BC896 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSVIKSIKAR EILNSRGNPT VEVDLYTEKD GVVSSFRAAV PSGASTGIYE AVELRDGDKS 

        70         80         90        100        110        120 
RYLGKGVLKA IKNILEVIQP AVIGKSVSDQ AAIDKLMIDL DGTPNKGKLG ANAILAVSLA 

       130        140        150        160        170        180 
VCRAGAADRN LPLYKYISEI AGTKMRLPVP AFNVINGGSH AGNKLAMQEF MILPVGAKDF 

       190        200        210        220        230        240 
NEAYRMGSEV YHNLKNVISG RYGQDAINVG DEGGFAPPIQ SNKEGLELLK LAIEKAGYTG 

       250        260        270        280        290        300 
LVKIGMDCAA SEFKVENGYD LDFKTKNNDG SAVISGEKLG DLYREFIKEY PIISIEDPFD 

       310        320        330        340        350        360 
QDDWESYTKL TASVDIQIVG DDLLVTNPER IKTGIEKKAC NALLLKVNQI GSVTESIRAA 

       370        380        390        400        410        420 
LDSKNASWGV MVSHRSGETE DTFIADLVVG LGTGQIKTGA PCRSERLAKY NQLVRINEEL 

       430 
GENHNYAGLT FRKF
Q54RK5 in FASTA format

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