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UniProtKB/Swiss-Prot entry Q54RE8


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name KMO_DICDI
Primary accession number Q54RE8
Secondary accession numbers None
Integrated into Swiss-Prot on April 29, 2008
Sequence was last modified on May 24, 2005 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 24)
Name and origin of the protein
Protein name Kynurenine 3-monooxygenase
Synonyms EC 1.14.13.9
Kynurenine 3-hydroxylase
Gene name
Name: kmo
ORFNames: DDB_G0283173
From
Dictyostelium discoideum (Slime mold) [TaxID: 44689] 
Taxonomy Eukaryota; Amoebozoa; Mycetozoa; Dictyosteliida; Dictyostelium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AX4;
DOI=10.1038/nature03481; PubMed=15875012 [NCBI, ExPASy, EBI, Israel, Japan]
Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
"The genome of the social amoeba Dictyostelium discoideum.";
Nature 435:43-57(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AAFI02000051; EAL65825.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_639197.1; -.
3D structure databases
ModBase Q54RE8.
Organism-specific databases
dictyBase DDB0231360; kmo.
Ontologies
GO
GO:0005739; Cellular component: mitochondrion (inferred from electronic annotation from UniProtKB-KW).
GO:0004502; Molecular function: kynurenine 3-monooxygenase activity (inferred from electronic annotation from EC).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR006076; FAD-dep_OxRdtase.
IPR003042; Rng_hydrolase.
Graphical view of domain structure.
Pfam PF01266; DAO; 1.
Pfam graphical view of domain structure.
PRINTS PR00420; RNGMNOXGNASE.
ProtoNet Q54RE8.
Genome annotation databases
GeneID 3390740; -.
KEGG ddi:DDB_0231360; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; FAD; Mitochondrion; Monooxygenase; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   460  460     Kynurenine 3-monooxygenase. PRO_0000331234
Sequence information
Length: 460 AA [This is the length of the unprocessed precursor] Molecular weight: 52261 Da [This is the MW of the unprocessed precursor] CRC64: AA02D3F26286A2A3 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MDILLNKPIT IVGGGLAGSA LALLLGQKGF PIQVIEKRPK QSENIRARSI NLALSDRGVK 

        70         80         90        100        110        120 
TLTKTGYVDD ILKIAIPMKG RMIHSLDSVQ TFQAYSSDSN KHLYSVSRQL LNDRLREHTE 

       130        140        150        160        170        180 
KLENVKFIFS DACKSIDLKQ CTIQTQDSNQ TIEASTIIGC DGAFSAVRGS MVKLDRQDYS 

       190        200        210        220        230        240 
QSYLKHGYKE LCIPSGPNQT FQIDKNSLHI WPRGSFMMIA LPNIDGSFTC TLFFPFDGPL 

       250        260        270        280        290        300 
SFSSLDTREK VDQFFKDYFP DAYKLMPDLL DDYFENPTSS LVTVKTEPYH YQGKVVLVGD 

       310        320        330        340        350        360 
AAHAIVPFYG QGMNAAFEDV LELFNCFEDK SLYPSSTDKP FDNDHFNNIY KKYQENRKAN 

       370        380        390        400        410        420 
SDAIAEMAVE NFFEMRDHVG DALFLFKKKV EHLLEVKFPS RYISRYELIS FSTQPYAYAQ 

       430        440        450        460 
KIGLANQQIL NELVKGNDDY NIEKIDLVLA DQLIKKYLNK 

Q54RE8 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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NPSA logo NPSA Sequence analysis tools

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