|
|
|
|
|
|
[1]
|
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AX4;
DOI=10.1038/nature03481; PubMed=15875012 [NCBI, ExPASy, EBI, Israel, Japan]
Eichinger L.,
Pachebat J.A.,
Gloeckner G.,
Rajandream M.A.,
Sucgang R.,
Berriman M.,
Song J.,
Olsen R.,
Szafranski K.,
Xu Q.,
Tunggal B.,
Kummerfeld S.,
Madera M.,
Konfortov B.A.,
Rivero F.,
Bankier A.T.,
Lehmann R.,
Hamlin N.,
Davies R., ![]()
Gaudet P.,
Fey P.,
Pilcher K.,
Chen G.,
Saunders D.,
Sodergren E.J.,
Davis P.,
Kerhornou A.,
Nie X.,
Hall N.,
Anjard C.,
Hemphill L.,
Bason N.,
Farbrother P.,
Desany B.,
Just E.,
Morio T.,
Rost R.,
Churcher C.M.,
Cooper J.,
Haydock S.,
van Driessche N.,
Cronin A.,
Goodhead I.,
Muzny D.M.,
Mourier T.,
Pain A.,
Lu M.,
Harper D.,
Lindsay R.,
Hauser H.,
James K.D.,
Quiles M.,
Madan Babu M.,
Saito T.,
Buchrieser C.,
Wardroper A.,
Felder M.,
Thangavelu M.,
Johnson D.,
Knights A.,
Loulseged H.,
Mungall K.L.,
Oliver K.,
Price C.,
Quail M.A.,
Urushihara H.,
Hernandez J.,
Rabbinowitsch E.,
Steffen D.,
Sanders M.,
Ma J.,
Kohara Y.,
Sharp S.,
Simmonds M.N.,
Spiegler S.,
Tivey A.,
Sugano S.,
White B.,
Walker D.,
Woodward J.R.,
Winckler T.,
Tanaka Y.,
Shaulsky G.,
Schleicher M.,
Weinstock G.M.,
Rosenthal A.,
Cox E.C.,
Chisholm R.L.,
Gibbs R.A.,
Loomis W.F.,
Platzer M.,
Kay R.R.,
Williams J.G.,
Dear P.H.,
Noegel A.A.,
Barrell B.G.,
Kuspa A.;
"The genome of the social amoeba Dictyostelium discoideum.";
Nature 435:43-57(2005).
|
|
|
|
- FUNCTION: Reduces the C14=C15 double bond of 4,4-dimethyl-cholesta-8,14,24-trienol to produce 4,4-dimethyl-cholesta-8,24-dienol (By similarity).
- CATALYTIC ACTIVITY: 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NADP+ = 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol + NADPH.
- PATHWAY: Steroid biosynthesis; zymosterol biosynthesis; zymosterol from lanosterol: step 2/6.
- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential).
- SIMILARITY: Belongs to the ERG4/ERG24 family.
|
|
|
|
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Length: 462 AA [This is the length of the unprocessed precursor] |
Molecular weight: 53763 Da [This is the MW of the unprocessed precursor] |
CRC64: F414DFF497147FA1 [This is a checksum on the sequence] |
|
10 20 30 40 50 60
MSAVRNRNNV EKQSNNGAQL TEVQKKELAD LQKVHPANEF GGIIGTFLLT FILPVVVYWI
70 80 90 100 110 120
WASIEFNNGY LLRPETLSVE GVKAFLAQLY HYVITYAYPT KEAAIIYFSW FGFQAFLQHV
130 140 150 160 170 180
VPGRKVLGSP LPGGARLEYT LNGWASWWIT LIVIPIAIYF GLFKATILID NYAPMMTVVN
190 200 210 220 230 240
IWSFVFTFLL KIHAKLKGEE ERMSGHFFYD FWMGFARNPR IGSFDLKLFC EARPGLILWV
250 260 270 280 290 300
LMNFSIAAKQ LEVYGEISLS VILVCCFHFW YIADYYYHEE AILTTMDIIT EKFGYMLVYG
310 320 330 340 350 360
DLSWVPFTYC FQCYYLYKHL VNGAPLHISI GYAIFVVSLK CFGFYLFRWV NSQKHDFRRN
370 380 390 400 410 420
PEAPVWGKPA EFILTKRGTK LLCSGFWGIC RHLNYTGDII LSWAWCLPCQ FDSLAPYFYG
430 440 450 460
IYFTSLDLHR CWRDHNACLV KYGDDWRAYC KRVPYNFIPG LI
|
Q54PP1 in FASTA format |
|
ExPASy Home page
CBR Canada
