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UniProtKB/Swiss-Prot entry Q38X26

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PYRC_LACSS
Primary accession number Q38X26
Secondary accession numbers None
Integrated into Swiss-Prot on January 15, 2008
Sequence was last modified on November 22, 2005 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 25)
Name and origin of the protein
Protein name Dihydroorotase
Synonyms DHOase
EC 3.5.2.3
Gene name
Name: pyrC
OrderedLocusNames: LSA0953
From
Lactobacillus sakei subsp. sakei (strain 23K) [TaxID: 314315] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/nbt1160; PubMed=16273110 [NCBI, ExPASy, EBI, Israel, Japan]
Chaillou S., Champomier-Verges M.-C., Cornet M., Crutz-Le Coq A.-M., Dudez A.-M., Martin V., Beaufils S., Darbon-Rongere E., Bossy R., Loux V., Zagorec M.;
"The complete genome sequence of the meat-borne lactic acid bacterium Lactobacillus sakei 23K.";
Nat. Biotechnol. 23:1527-1533(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CR936503; CAI55255.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_395564.1; -.
3D structure databases
ModBase Q38X26.
Enzyme and pathway databases
BioCyc LSAK314315:LSA0953-MON; -.
Ontologies
GO
GO:0004151; Molecular function: dihydroorotase activity (inferred from electronic annotation from HAMAP).
GO:0008270; Molecular function: zinc ion binding (inferred from electronic annotation from HAMAP).
GO:0006221; Biological process: pyrimidine nucleotide biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00220; -; 1.
PBIL [Tree]
InterPro IPR006680; Amidohydro_1.
IPR004722; DHOmult.
IPR002195; Dihydroorotase_CS.
Graphical view of domain structure.
Pfam PF01979; Amidohydro_1; 1.
Pfam graphical view of domain structure.
ProDom PD000518; DHOase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR00857; pyrC_multi; 1.
PROSITE PS00482; DIHYDROOROTASE_1; FALSE_NEG.
PS00483; DIHYDROOROTASE_2; 1.
BLOCKS Q38X26.
ProtoNet Q38X26.
Genome annotation databases
GeneID 3777487; -.
GenomeReviews CR936503_GR; LSA0953.
KEGG lsa:LSA0953; -.
Phylogenomic databases
HOGENOM Q38X26; -.
Genome annotation databases
CMR Q38X26; LSA0953.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Hydrolase; Metal-binding; Pyrimidine biosynthesis; Zinc.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   429  429     Dihydroorotase. PRO_1000024092
METAL   62    62        Zinc 1 (By similarity). 
METAL   64    64        Zinc 1 (By similarity). 
METAL   144   144        Zinc 1; via carbamate group (By similarity). 
METAL   144   144        Zinc 2; via carbamate group (By similarity). 
METAL   181   181        Zinc 2 (By similarity). 
METAL   234   234        Zinc 2 (By similarity). 
METAL   307   307        Zinc 1 (By similarity). 
MOD_RES   144   144        N6-carboxylysine (By similarity). 
Sequence information
Length: 429 AA [This is the length of the unprocessed precursor] Molecular weight: 45772 Da [This is the MW of the unprocessed precursor] CRC64: 7F40A19F45F0FEEB [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MYRLIQNGQL LIDDQLVKRD IAIDEKGRIT AIEAQITPTD EPTETIFDAQ GALVSAGLID 

        70         80         90        100        110        120 
GHVHFRDPGF TDKETLQTGS QAAAHGGYTS VIAMPNLNPV PDNLSDFKTL VARNQTETSV 

       130        140        150        160        170        180 
HTYQFAPITG DLVNNDLVDM PAFKAAGAAG FTNDGHGVQD AQTMYLAMQQ AAAIDAPIVA 

       190        200        210        220        230        240 
HVEDISLVNG GVIHDGAAAK RLNVPGIPSV SESAQVARDI ELARATGVHY HICHISTKET 

       250        260        270        280        290        300 
VALVRRAKAD GVNITCEVTP HHLLLDDRSI ISDDTMLKMN PPLRTLADRQ SLWAGLMDGT 

       310        320        330        340        350        360 
IDVIATDHAP HTAAEKSQSL LQAPFGIVGS ETAFSLLYTH LVVNGPFSLA QLLAKMTTVP 

       370        380        390        400        410        420 
AQVFNLPAAG QLRVGDQADI AVFNLTQPTT IQATDFQSKG HNTPFIGETV LGGTELTLVA 


GQVAYQRSK
Q38X26 in FASTA format

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