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UniProtKB/Swiss-Prot entry Q37383


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NDUS3_ACACA
Primary accession number Q37383
Secondary accession numbers None
Integrated into Swiss-Prot on December 15, 1998
Sequence was last modified on November 1, 1996 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 51)
Name and origin of the protein
Protein name NADH-ubiquinone oxidoreductase subunit 9
Synonyms EC 1.6.5.3
EC 1.6.99.3
Gene name
Name: NAD9
From
Acanthamoeba castellanii (Amoeba) [TaxID: 5755] 
Encoded on Mitochondrion.
Taxonomy Eukaryota; Amoebozoa; Centramoebida; Acanthamoebidae; Acanthamoeba.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=ATCC 30010 / Neff;
DOI=10.1006/jmbi.1994.0043; PubMed=7844823 [NCBI, ExPASy, EBI, Israel, Japan]
Burger G., Plante I., Lonergan K.M., Gray M.W.;
"The mitochondrial DNA of the amoeboid protozoon, Acanthamoeba castellanii: complete sequence, gene content and genome organization.";
J. Mol. Biol. 245:522-537(1995).
Comments
  • FUNCTION: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
  • CATALYTIC ACTIVITY: NADH + ubiquinone = NAD+ + ubiquinol.
  • CATALYTIC ACTIVITY: NADH + acceptor = NAD+ + reduced acceptor.
  • SUBUNIT: Complex I is composed of about 30 different subunits.
  • SUBCELLULAR LOCATION: Mitochondrion inner membrane.
  • SIMILARITY: Belongs to the complex I 30 kDa subunit family.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U12386; AAD11853.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S53861; S53861.
RefSeq NP_042560.1; -.
3D structure databases
ModBase Q37383.
Ontologies
GO
GO:0005746; Cellular component: mitochondrial respiratory chain (inferred from electronic annotation from UniProtKB-KW).
GO:0006810; Biological process: transport (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR010218; NADH_DH_csu.
IPR001268; NADH_DHase_Ub_30kDa_su.
Graphical view of domain structure.
Pfam PF00329; Complex1_30kDa; 1.
Pfam graphical view of domain structure.
ProDom PD001581; Complex1_30K; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR01961; NuoC_fam; 1.
PROSITE PS00542; COMPLEX1_30K; 1.
BLOCKS Q37383.
ProtoNet Q37383.
Genome annotation databases
GeneID 1734055; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane; NAD; Oxidoreductase; Respiratory chain; Transport; Ubiquinone.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   195  195     NADH-ubiquinone oxidoreductase subunit 9. PRO_0000118644
Sequence information
Length: 195 AA [This is the length of the unprocessed precursor] Molecular weight: 23349 Da [This is the MW of the unprocessed precursor] CRC64: 449A900545A0F073 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MGLNFFMSRK IYYIKLLTGL YKKFIKALIV KKNESNNAYL LVETANFYNL VFSLQRSSLT 

        70         80         90        100        110        120 
QFKVLNDVCI VDYPEKIDRF ELSYNLSSIK YNFRIFIKTY TSAYVPSIST LFNSANWIER 

       130        140        150        160        170        180 
ECWDMFGVFF TNHPDLRRIL TDYGFEGFPL RKDFPLTGYI EIRYDDEKAN IVYEPLELSQ 

       190 
EYRLFNFTSP WEKIK 

Q37383 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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NPSA logo NPSA Sequence analysis tools

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