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UniProtKB/Swiss-Prot entry Q2UKB8


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MCR1_ASPOR
Primary accession number Q2UKB8
Secondary accession numbers None
Integrated into Swiss-Prot on April 29, 2008
Sequence was last modified on January 24, 2006 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 22)
Name and origin of the protein
Protein name NADH-cytochrome b5 reductase 2
Synonyms EC 1.6.2.2
Mitochondrial cytochrome b reductase
Gene name
Name: mcr1
ORFNames: AO090003000873
From
Aspergillus oryzae [TaxID: 5062] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Trichocomaceae; mitosporic Trichocomaceae; Aspergillus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 42149 / RIB 40;
DOI=10.1038/nature04300; PubMed=16372010 [NCBI, ExPASy, EBI, Israel, Japan]
Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K., Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H., Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E., Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D., Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A., Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y., Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H., Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T., Takahashi M., Takase K., Terabayashi Y., Wortman J.R., Yamada O., Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y., Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N., Kikuchi H.;
"Genome sequencing and analysis of Aspergillus oryzae.";
Nature 438:1157-1161(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AP007155; BAE57997.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_001819999.1; -.
3D structure databases
ModBase Q2UKB8.
Ontologies
GO
GO:0016021; Cellular component: integral to membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0005741; Cellular component: mitochondrial outer membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0004128; Molecular function: cytochrome-b5 reductase activity (inferred from electronic annotation from EC).
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR001834; Cyt_B5_reductase.
IPR001709; FPN_cyt_redctse.
IPR008333; OxRdtase_FAD-bd.
IPR001433; OxRdtase_FAD/NAD_bd.
Graphical view of domain structure.
Pfam PF00970; FAD_binding_6; 1.
PF00175; NAD_binding_1; 1.
Pfam graphical view of domain structure.
PRINTS PR00406; CYTB5RDTASE.
PR00371; FPNCR.
PROSITE PS51384; FAD_FR; 1.
PROSITE graphical view of domain structure (profiles).
Genome annotation databases
GeneID 5991982; -.
KEGG aor:AO090003000873; -.
Other
ProtoNet Q2UKB8.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; FAD; Flavoprotein; Membrane; Mitochondrion; Mitochondrion outer membrane; NAD; Oxidoreductase; Transmembrane.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   323  323     NADH-cytochrome b5 reductase 2. PRO_0000330173
TRANSMEM   30    46  17     Potential. 
DOMAIN   72   177  106     FAD-binding FR-type. 
NP_BIND   180   215  36     FAD (By similarity). 
Sequence information
Length: 323 AA [This is the length of the unprocessed precursor] Molecular weight: 36322 Da [This is the MW of the unprocessed precursor] CRC64: 35E61ADC5100DB2C [This is a checksum on the sequence]
        10         20         30         40         50         60 
MFARQTFRCA QPLRQSFRKY STEAPKAKSL APIYTAVGLT GLSVGLYRYY YGAGATAEAP 

        70         80         90        100        110        120 
VERAKVFTGG DQGWVDLKLS EIEVLSHNTK RLRFEFEDKE AVSGVTIASA LLTKFKPVGA 

       130        140        150        160        170        180 
EKAVLRPYTP TSDEDQPGYL DLVVKVYPNG PMSEHLHSMN VDQRLSFKGP LPKYQWETNK 

       190        200        210        220        230        240 
HEHIALIAGG TGITPMYQLI RQIFKNPDDK TKVTLVYGNV TEDDILLKKE LQDLENTYPQ 

       250        260        270        280        290        300 
RFKAFYLLDK PPKEWTGGKG YINKELLKTV LPEPKEENQK IFVCGPPGLY NAVSGNKVSP 

       310        320 
KDQGELSGIL KELGYNKDQV YKF 

Q2UKB8 in FASTA format

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