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UniProtKB/Swiss-Prot entry Q28616

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AMHR2_RABIT
Primary accession number Q28616
Secondary accession numbers None
Integrated into Swiss-Prot on November 28, 2006
Sequence was last modified on November 1, 1996 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 58)
Name and origin of the protein
Protein name Anti-Muellerian hormone type-2 receptor [Precursor]
Synonyms EC 2.7.11.30
Anti-Muellerian hormone type II receptor
AMH type II receptor
MIS type II receptor
MISRII
MRII
Gene name
Name: AMHR2
From
Oryctolagus cuniculus (Rabbit) [TaxID: 9986] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Ovary;
DOI=10.1210/me.8.8.1006; PubMed=7997230 [NCBI, ExPASy, EBI, Israel, Japan]
di Clemente N., Wilson C., Faure E., Boussin L., Carmillo P., Tizard R., Picard J.-Y., Vigier B., Josso N., Cate R.;
"Cloning, expression, and alternative splicing of the receptor for anti-Muellerian hormone.";
Mol. Endocrinol. 8:1006-1020(1994).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U15025; AAA21875.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_001076263.1; -.
UniGene Ocu.1823
3D structure databases
HSSP P36897; 1IAS. [HSSP ENTRY / PDB]
ModBase Q28616.
Family and domain databases
InterPro IPR017193; Anti-muellerian_hrmn_rcpt_II.
IPR015771; Anti-muellerian_hrmn_rcpt_II_C.
IPR000719; Prot_kinase_core.
IPR017441; Protein_kinase_ATP_bd_CS.
IPR017442; Se/Thr_pkinase-rel.
IPR008271; Ser_thr_pkin_AS.
Graphical view of domain structure.
PANTHER PTHR23255:SF4; MIS_II_R; 1.
Pfam PF00069; Pkinase; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF037392; AMHRII; 1.
ProDom PD000001; Prot_kinase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
PROSITE PS00107; PROTEIN_KINASE_ATP; FALSE_NEG.
PS50011; PROTEIN_KINASE_DOM; 1.
PS00108; PROTEIN_KINASE_ST; FALSE_NEG.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q28616.
Genome annotation databases
GeneID 100009599; -.
Phylogenomic databases
HOVERGEN Q28616; -.
Other
ProtoNet Q28616.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Glycoprotein; Kinase; Magnesium; Manganese; Membrane; Metal-binding; Nucleotide-binding; Receptor; Serine/threonine-protein kinase; Signal; Transferase; Transmembrane.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
SIGNAL   1    17  17     Potential. 
CHAIN   18   569  552     Anti-Muellerian hormone type-2 receptor. PRO_0000260266
TOPO_DOM   18   148  131     Extracellular (Potential). 
TRANSMEM   149   169  21     Potential. 
TOPO_DOM   170   569  400     Cytoplasmic (Potential). 
DOMAIN   201   511  311     Protein kinase. 
NP_BIND   207   215  9     ATP (By similarity). 
COMPBIAS   149   162  14     Poly-Leu. 
ACT_SITE   331   331        Proton acceptor (By similarity). 
BINDING   228   228        ATP (By similarity). 
CARBOHYD   66    66        N-linked (GlcNAc...) (Potential). 
CARBOHYD   119   119        N-linked (GlcNAc...) (Potential). 
Sequence information
Length: 569 AA [This is the length of the unprocessed precursor] Molecular weight: 61099 Da [This is the MW of the unprocessed precursor] CRC64: 388800F0ECAA5AAB [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MLGTLGLWAL LPAAVQAPPN RRTCVFFEAP GVRGSTKTLG ELLDAGPGPP RVIRCLYSRC 

        70         80         90        100        110        120 
CFGIWNLTRD QAQVEMQGCR DSDEPGCESL SCDPSPRARA SSGSTLFTCS CGADFCNANY 

       130        140        150        160        170        180 
SHLPPLGGPG TPGPQGPQAA PGESPWMALA LLGLVLLLLL LLGGIVVALL QRKAYRVQSG 

       190        200        210        220        230        240 
PEPEPDSGRD CSEELPELPQ LCFSQVIREG GHAAVWAGQL QGELVAIKVF PRRAVAQFRA 

       250        260        270        280        290        300 
ERALYELPGL QHNHVVRFIA AGQGGPGPLP SGPLLVLELH PKGSLCQYLS QHTSDWGSSL 

       310        320        330        340        350        360 
RMALSLAQGL AFLHEERWQD GQYKPGIAHR DLSSQNVLIR EDGSCAIGDL GLALVLPGFA 

       370        380        390        400        410        420 
QPRAWAPPQP RGPAAIMEAG TQRYMAPELL DKSLDLQDWG TALRRADVYS LALLLWEILS 

       430        440        450        460        470        480 
RCPDLRPDGR PPPFQLAYEA ELGSAPTTCE LWALAVEERR RPDIPSSWCC FATDPGGLRE 

       490        500        510        520        530        540 
LLEDCWDADP EARLTAECVQ QRLVALVHPQ EAQPCPEGRP HSHPEDWPPA PAPAPALLPG 

       550        560 
SPQPGACHFG VQQGLCSRNP GAACASSDV
Q28616 in FASTA format

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