PROTEIN SEQUENCE, AND REACTIVE SITE.
TISSUE=Seed;
PubMed=14515156 [NCBI, ExPASy, EBI, Israel, Japan]
Polanowski A., Wilimowska-Pelc A., Kowalska J., Grybel J., Zelazko M., Wilusz T.;
"Non-conventional affinity chromatography of serine proteinases and their inhibitors.";
Acta Biochim. Pol. 50:765-773(2003).

Comments

FUNCTION: Inhibits trypsin.
SUBCELLULAR LOCATION: Secreted.
DOMAIN: The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin (By similarity).
SIMILARITY: Belongs to the protease inhibitor I7 (squash-type serine protease inhibitor) family [view classification].

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

3D structure databases
HSSP	P01074; 1CTI. [HSSP ENTRY / PDB]
ModBase	P83394.
Family and domain databases
InterPro	IPR000737; Prot_inh_squash. Graphical view of domain structure.
Pfam	PF00299; Squash; 1. Pfam graphical view of domain structure.
PRINTS	PR00293; SQUASHINHBTR.
ProDom	PD003401; Prot_inh_squash; 1. [Domain structure / List of seq. sharing at least 1 domain]
SMART	SM00286; PTI; 1. SMART graphical view of domain structure.
PROSITE	PS00286; SQUASH_INHIBITOR; 1.
BLOCKS	P83394.
Other
ProtoNet	P83394.
UniRef	View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Direct protein sequencing; Knottin; Protease inhibitor; Secreted; Serine protease inhibitor.

Features

Feature table viewer

Sequence information

Length: 29 AA [This is the length of the unprocessed precursor]

Molecular weight: 3195 Da [This is the MW of the unprocessed precursor]

CRC64: D5FEFF8A5FEDCC2F [This is a checksum on the sequence]

        10         20 
RICPRILMEC KADSDCLAQC ICEESGFCG

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools