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UniProtKB/Swiss-Prot entry P47193

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name VAMP2_XENLA
Primary accession number P47193
Secondary accession number Q5D065
Integrated into Swiss-Prot on November 1, 1995
Sequence was last modified on January 23, 2007 (Sequence version 3)
Annotations were last modified on    June 16, 2009 (Entry version 65)
Name and origin of the protein
Protein name Vesicle-associated membrane protein 2
Synonyms VAMP-2
Synaptobrevin-2
SYBII
Gene name
Name: vamp2
From
Xenopus laevis (African clawed frog) [TaxID: 8355] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [MRNA].
Wang X.-H., Poo M.-M.;
Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases.
[2]
 NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Embryo, and Testis;
NIH - Xenopus Gene Collection (XGC) project;
Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
[3]
 NUCLEOTIDE SEQUENCE [MRNA] OF 33-114.
TISSUE=Embryo;
PubMed=7601005 [NCBI, ExPASy, EBI, Israel, Japan]
Knecht A.K., Good P.J., Dawid I.B., Harland R.M.;
"Dorsal-ventral patterning and differentiation of noggin-induced neural tissue in the absence of mesoderm.";
Development 121:1927-1935(1995).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AF035017; AAB88138.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BC060344; AAH60344.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BC123114; AAI23115.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
U16801; AAA81376.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_001080944.1; -.
UniGene Xl.234
3D structure databases
HSSP P19065; 1F83. [HSSP ENTRY / PDB]
SMR P47193; 23-91.
ModBase P47193.
Organism-specific databases
Xenbase XB-FEAT-5788094; vamp2.
Ontologies
GO
GO:0030054; Cellular component: cell junction (inferred from electronic annotation from UniProtKB-SubCell).
GO:0016021; Cellular component: integral to membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0030141; Cellular component: secretory granule (inferred from electronic annotation from UniProtKB-SubCell).
GO:0030672; Cellular component: synaptic vesicle membrane (inferred from electronic annotation from UniProtKB-SubCell).
GO:0019717; Cellular component: synaptosome (inferred from electronic annotation from UniProtKB-SubCell).
GO:0016192; Biological process: vesicle-mediated transport (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR001388; Synaptobrevin.
IPR016444; Synaptobrevin_met/fun.
Graphical view of domain structure.
Pfam PF00957; Synaptobrevin; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF005409; Synaptobrevin_euk; 1.
PRINTS PR00219; SYNAPTOBREVN.
ProDom PD001229; Synaptobrevin; 1.
[Domain structure / List of seq. sharing at least 1 domain]
PROSITE PS00417; SYNAPTOBREVIN; 1.
PS50892; V_SNARE; 1.
PROSITE graphical view of domain structure (profiles).
Genome annotation databases
GeneID 394287; -.
KEGG xla:394287; -.
Phylogenomic databases
HOVERGEN P47193; -.
Other
ProtoNet P47193.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Acetylation; Cell junction; Coiled coil; Cytoplasmic vesicle; Membrane; Synapse; Synaptosome; Transmembrane.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
INIT_MET   1     1        Removed (By similarity). 
CHAIN   2   114  113     Vesicle-associated membrane protein 2. PRO_0000206727
TOPO_DOM   2    92  91     Cytoplasmic (Potential). 
TRANSMEM   93   111  19     Anchor for type IV membrane protein (Potential). 
TOPO_DOM   112   114  3     Vesicular (Potential). 
DOMAIN   29    89  61     v-SNARE coiled-coil homology. 
MOD_RES   2     2        N-acetylserine (By similarity). 
Sequence information
Length: 114 AA [This is the length of the unprocessed precursor] Molecular weight: 12473 Da [This is the MW of the unprocessed precursor] CRC64: AEF2EDDCDF2D1DBF [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSAPAAGPPA AAPGDGAPQG PPNLTSNRRL QQTQAQVDEV VDIMRVNVDK VLERDTKLSE 

        70         80         90        100        110 
LDDRADALQA GASQFETSAA KLKRKYWWKN MKMMIIMGVI CAIILIIIIV YFST
P47193 in FASTA format

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