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UniProtKB/Swiss-Prot entry P24794

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name COX1_BETVU
Primary accession number P24794
Secondary accession numbers None
Integrated into Swiss-Prot on March 1, 1992
Sequence was last modified on February 1, 1996 (Sequence version 2)
Annotations were last modified on    November 25, 2008 (Entry version 62)
Name and origin of the protein
Protein name Cytochrome c oxidase subunit 1
Synonyms EC 1.9.3.1
Cytochrome c oxidase polypeptide I
Gene name
Name: COX1
Synonyms: COXI
From
Beta vulgaris (Sugar beet) [TaxID: 161934] 
Encoded on Mitochondrion.
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; Caryophyllales; Amaranthaceae; Beta.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=cv. TK81-O;
DOI=10.1007/BF00336484; PubMed=1651175 [NCBI, ExPASy, EBI, Israel, Japan]
Senda M., Harada T., Mikami T., Sugiura M., Kinoshita T.;
"Genomic organization and sequence analysis of the cytochrome oxidase subunit II gene from normal and male-sterile mitochondria in sugar beet.";
Curr. Genet. 19:175-181(1991).
[2]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Harada T., Mikami T., Kinoshita T.;
"Nucleotide sequence of cytochrome c oxidase subunit I gene of sugar beet mitochondria.";
Proc. Sugar Beet Res. 29:15-21(1987).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X57693; CAA40874.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
M57645; AAA87330.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S14138; S14138.
3D structure databases
HSSP P00396; 2OCC. [HSSP ENTRY / PDB]
ModBase P24794.
Ontologies
GO
GO:0016021; Cellular component: integral to membrane (inferred from electronic annotation from InterPro).
GO:0005746; Cellular component: mitochondrial respiratory chain (inferred from electronic annotation from UniProtKB-KW).
GO:0005507; Molecular function: copper ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0004129; Molecular function: cytochrome-c oxidase activity (inferred from electronic annotation from InterPro).
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0020037; Molecular function: heme binding (inferred from electronic annotation from InterPro).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from InterPro).
GO:0009060; Biological process: aerobic respiration (inferred from electronic annotation from InterPro).
GO:0022900; Biological process: electron transport chain (inferred from electronic annotation from UniProtKB-KW).
GO:0006810; Biological process: transport (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR000883; COX1.
IPR014241; COX1_bac-type.
Graphical view of domain structure.
Gene3D G3DSA:1.20.210.10; COX1; 1.
PANTHER PTHR10422; COX1; 1.
Pfam PF00115; COX1; 1.
Pfam graphical view of domain structure.
PRINTS PR01165; CYCOXIDASEI.
TIGRFAMs TIGR02891; CtaD_CoxA; 1.
PROSITE PS50855; COX1; 1.
PS00077; COX1_CUB; 1.
PROSITE graphical view of domain structure (profiles).
ProtoNet P24794.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Copper; Electron transport; Heme; Iron; Membrane; Metal-binding; Mitochondrion; Mitochondrion inner membrane; Oxidoreductase; Respiratory chain; Transmembrane; Transport.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   524  524     Cytochrome c oxidase subunit 1. PRO_0000183293
TRANSMEM   18    38  21     Potential. 
TRANSMEM   66    86  21     Potential. 
TRANSMEM   103   123  21     Potential. 
TRANSMEM   148   168  21     Potential. 
TRANSMEM   186   206  21     Potential. 
TRANSMEM   237   257  21     Potential. 
TRANSMEM   269   289  21     Potential. 
TRANSMEM   312   332  21     Potential. 
TRANSMEM   340   360  21     Potential. 
TRANSMEM   379   399  21     Potential. 
TRANSMEM   414   434  21     Potential. 
TRANSMEM   458   478  21     Potential. 
METAL   64    64        Iron (heme A axial ligand) (Probable). 
METAL   243   243        Copper B (Probable). 
METAL   247   247        Copper B (Probable). 
METAL   292   292        Copper B (Probable). 
METAL   293   293        Copper B (Probable). 
METAL   378   378        Iron (heme A3 axial ligand) (Probable). 
METAL   380   380        Iron (heme A axial ligand) (Probable). 
CROSSLNK   243   247        1'-histidyl-3'-tyrosine (His-Tyr) (By similarity). 
CONFLICT   1     9        MTNLVRWLF -> MAV (in Ref. 2; AAA87330). 
CONFLICT   220   227        TTFFDPAG -> RPFLIRW (in Ref. 2; AAA87330). 
CONFLICT   501   503        EWM -> ND (in Ref. 2; AAA87330). 
Sequence information
Length: 524 AA [This is the length of the unprocessed precursor] Molecular weight: 57581 Da [This is the MW of the unprocessed precursor] CRC64: A862089EE5C476EA [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTNLVRWLFS TNHKDIGTLY FIFGAIAGVM GTCFSVLIRM ELARPGDQIL GGNHQLYNVL 

        70         80         90        100        110        120 
ITAHAFLMIF FMVMPAMIGG FGNWFVPILI GAPDMAFPRL NNISFWLLPP SLLLLLSSAL 

       130        140        150        160        170        180 
VEVGSGTGWT VYPPLSGITS HSGGAVDLAI FSLHLSGVSS ILGSINFITT IFNMRGPGMT 

       190        200        210        220        230        240 
MHRLPLFVWS VLVTAFLLLL SLPVLAGAIT MLLTDRNFNT TFFDPAGGGD PILYQHLFWF 

       250        260        270        280        290        300 
FGHPEVYILI LPGFGIISHI VSTFSGKPVF GYLGMVYAMI SIGVLGFLVW AHHMFTVGLD 

       310        320        330        340        350        360 
VDTRAYFTAA TMIIAVPTGI KIFSWIATMW GGSIQYKTPM LFAVGFIFLF TVGGLTGIVL 

       370        380        390        400        410        420 
ANSGLDIALH DTYYVVAHFH YVLSMGAVFA LFAGFYYWVG KIFGRTYPET LGQIHFWITF 

       430        440        450        460        470        480 
FGVNLTFFPM HFLGLSGMPR RIPDYPDAYA GWNALSSFGS YISVVGICCF FVVVTITLSS 

       490        500        510        520 
GKNKRCAPSP WAVEENSTTL EWMVQSPPAF HTFGELPAIK ETKS
P24794 in FASTA format

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