NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=M1286;
PubMed=3134196 [NCBI, ExPASy, EBI, Israel, Japan]
Heilmann H.J., Maegert H.-J., Gassen H.G.;
"Identification and isolation of glucose dehydrogenase genes of Bacillus megaterium M1286 and their expression in Escherichia coli.";
Eur. J. Biochem. 174:485-490(1988).

Comments

CATALYTIC ACTIVITY: Beta-D-glucose + NAD(P)⁺ = D-glucono-1,5-lactone + NAD(P)H.
SUBUNIT: Homotetramer.
SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

X12370; CAA30931.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

S00812; S00812.

3D structure databases

HSSP

P40288; 1GEE. [HSSP ENTRY / PDB]

SMR

P10528; 1-261.

ModBase

P10528.

Ontologies

GO:0005488;	Molecular function: binding (inferred from electronic annotation from InterPro).
GO:0047936;	Molecular function: glucose 1-dehydrogenase activity (inferred from electronic annotation from EC).
GO:0055114;	Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

InterPro

IPR002198; DHase_sc/Rdtase_SDR.
IPR002347; Glc/ribitol_DHase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.720; NAD(P)-bd; 1.

PANTHER

PTHR19410; ADH_short_C2; 1.

Pfam

PF00106; adh_short; 1.
Pfam graphical view of domain structure.

PRINTS

PR00081; GDHRDH.
PR00080; SDRFAMILY.

PROSITE

PS00061; ADH_SHORT; 1.

Other

ProtoNet

P10528.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

NADP; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 261`	`261`	`Glucose 1-dehydrogenase A.`	`PRO_0000054613`
`NP_BIND`	`11 35`	`25`	`NADP (By similarity).`
`ACT_SITE`	`158 158`		`Proton acceptor (By similarity).`
`BINDING`	`145 145`		`Substrate (By similarity).`

Sequence information

Length: 261 AA [This is the length of the unprocessed precursor]

Molecular weight: 28187 Da [This is the MW of the unprocessed precursor]

CRC64: 6FADDA3968DC417C [This is a checksum on the sequence]

        10         20         30         40         50         60 
MYTDLKDKVV VITGGSTGLG RAMAVRFGQE EAKVVINYYN NEEEALDAKK EVEEAGGQAI 

        70         80         90        100        110        120 
IVQGDVTKEE DVVNLVQTAI KEFGTLDVMI NNAGVENPVP SHELSLDNWN KVIDTNLTGA 

       130        140        150        160        170        180 
FLGSREAIKY FVENDIKGNV INMSSVHEMI PWPLFVHYAA SKGGMKLMTE TLALEYAPKG 

       190        200        210        220        230        240 
IRVNNIGPGA MNTPINAEKF ADPEQRADVE SMIPMGYIGK PEEVAAVAAF LASSQASYVT 

       250        260 
GITLFADGGM TKYPSFQAGR G

P10528 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools