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UniProtKB/Swiss-Prot entry P0A6J5


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DADA_ECOLI
Primary accession number P0A6J5
Secondary accession number P29011
Integrated into Swiss-Prot on March 29, 2005
Sequence was last modified on March 29, 2005 (Sequence version 1)
Annotations were last modified on    December 16, 2008 (Entry version 36)
Name and origin of the protein
Protein name D-amino acid dehydrogenase small subunit
Synonym EC 1.4.99.1
Gene name
Name: dadA
Synonyms: dadR
OrderedLocusNames: b1189, JW1178
From
Escherichia coli (strain K12) [TaxID: 83333] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=K12;
PubMed=7906689 [NCBI, ExPASy, EBI, Israel, Japan]
Lobocka M., Hennig J., Wild J., Klopotowski T.;
"Organization and expression of the Escherichia coli K-12 dad operon encoding the smaller subunit of D-amino acid dehydrogenase and the catabolic alanine racemase.";
J. Bacteriol. 176:1500-1510(1994).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
DOI=10.1093/dnares/3.3.137; PubMed=8905232 [NCBI, ExPASy, EBI, Israel, Japan]
Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K., Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S., Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H., Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G., Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M., Horiuchi T.;
"A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map.";
DNA Res. 3:137-155(1996).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K12 / MG1655 / ATCC 47076;
DOI=10.1126/science.277.5331.1453; PubMed=9278503 [NCBI, ExPASy, EBI, Israel, Japan]
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.;
"The complete genome sequence of Escherichia coli K-12.";
Science 277:1453-1474(1997).
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
DOI=10.1038/msb4100049; PubMed=16738553 [NCBI, ExPASy, EBI, Israel, Japan]
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.";
Mol. Syst. Biol. 2:E1-E5(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
L02948; AAC36880.1; -; Unassigned_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
U00096; AAC74273.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AP009048; BAA36044.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR B53383; B53383.
RefSeq AP_001814.1; -.
NP_415707.1; -.
3D structure databases
ModBase P0A6J5.
Enzyme and pathway databases
BioCyc EcoCyc:DALADEHYDROGA-MON; -.
MetaCyc:DALADEHYDROGA-MON; -.
Organism-specific databases
EchoBASE EB1379; -.
EcoGene EG11407; dadA.
Ontologies
GO
GO:0005886; Cellular component: plasma membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0008718; Molecular function: D-amino-acid dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0006524; Biological process: alanine catabolic process (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_01202; -; 1.
PBIL [Tree]
InterPro IPR006076; FAD-dep_OxRdtase.
Graphical view of domain structure.
Pfam PF01266; DAO; 1.
Pfam graphical view of domain structure.
ProDom PD000139; FAD_pyr_redox; 1.
[Domain structure / List of seq. sharing at least 1 domain]
Genome annotation databases
GeneID 945752; -.
GenomeReviews AP009048_GR; JW1178.
U00096_GR; b1189.
KEGG ecj:JW1178; -.
eco:b1189; -.
Phylogenomic databases
HOGENOM P0A6J5; -.
Genome annotation databases
CMR P0A6J5; b1189.
Other
ProtoNet P0A6J5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cell inner membrane; Cell membrane; Complete proteome; FAD; Flavoprotein; Iron; Membrane; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   432  432     D-amino acid dehydrogenase small subunit. PRO_0000166131
NP_BIND   3    17  15     FAD (Potential). 
Sequence information
Length: 432 AA [This is the length of the unprocessed precursor] Molecular weight: 47607 Da [This is the MW of the unprocessed precursor] CRC64: EE747358845B6280 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MRVVILGSGV VGVASAWYLN QAGHEVTVID REPGAALETS AANAGQISPG YAAPWAAPGV 

        70         80         90        100        110        120 
PLKAIKWMFQ RHAPLAVRLD GTQFQLKWMW QMLRNCDTSH YMENKGRMVR LAEYSRDCLK 

       130        140        150        160        170        180 
ALRAETNIQY EGRQGGTLQL FRTEQQYENA TRDIAVLEDA GVPYQLLESS RLAEVEPALA 

       190        200        210        220        230        240 
EVAHKLTGGL QLPNDETGDC QLFTQNLARM AEQAGVKFRF NTPVDQLLCD GEQIYGVKCG 

       250        260        270        280        290        300 
DEVIKADAYV MAFGSYSTAM LKGIVDIPVY PLKGYSLTIP IAQEDGAPVS TILDETYKIA 

       310        320        330        340        350        360 
ITRFDNRIRV GGMAEIVGFN TELLQPRRET LEMVVRDLYP RGGHVEQATF WTGLRPMTPD 

       370        380        390        400        410        420 
GTPVVGRTRF KNLWLNTGHG TLGWTMACGS GQLLSDLLSG RTPAIPYEDL SVARYSRGFT 

       430 
PSRPGHLHGA HS 

P0A6J5 in FASTA format

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