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UniProtKB/Swiss-Prot entry P0A252


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AHPC_SALTI
Primary accession number P0A252
Secondary accession number P19479
Integrated into Swiss-Prot on March 15, 2005
Sequence was last modified on January 23, 2007 (Sequence version 2)
Annotations were last modified on    December 16, 2008 (Entry version 27)
Name and origin of the protein
Protein name Alkyl hydroperoxide reductase subunit C
Synonyms EC 1.11.1.15
Peroxiredoxin
Thioredoxin peroxidase
Alkyl hydroperoxide reductase protein C22
Gene name
Name: ahpC
OrderedLocusNames: STY0653, t2260
From
Salmonella typhi [TaxID: 601] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Salmonella.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CT18;
DOI=10.1038/35101607; PubMed=11677608 [NCBI, ExPASy, EBI, Israel, Japan]
Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J., Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M., Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A., Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T., Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A., Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G.;
"Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18.";
Nature 413:848-852(2001).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 700931 / Ty2;
DOI=10.1128/JB.185.7.2330-2337.2003; PubMed=12644504 [NCBI, ExPASy, EBI, Israel, Japan]
Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R.;
"Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18.";
J. Bacteriol. 185:2330-2337(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AL627267; CAD05084.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE014613; AAO69862.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_455184.1; -.
NP_806002.1; -.
3D structure databases
SMR P0A252; 2-187.
ModBase P0A252.
Enzyme and pathway databases
BioCyc SENT209261:T2260-MON; -.
SENT220341:STY0653-MON; -.
Ontologies
GO
GO:0051920; Molecular function: peroxiredoxin activity (inferred from electronic annotation from EC).
GO:0045454; Biological process: cell redox homeostasis (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR000866; AhpC-TSA.
IPR017559; Peroxiredoxin.
IPR012335; Thioredoxin_fold.
Graphical view of domain structure.
Gene3D G3DSA:3.40.30.10; Thioredoxin_fold; 1.
Pfam PF00578; AhpC-TSA; 1.
Pfam graphical view of domain structure.
PROSITE PS51352; THIOREDOXIN_2; 1.
PROSITE graphical view of domain structure (profiles).
Genome annotation databases
GeneID 1069351; -.
1247116; -.
GenomeReviews AE014613_GR; t2260.
AL513382_GR; STY0653.
KEGG stt:t2260; -.
sty:STY0653; -.
Phylogenomic databases
HOGENOM P0A252; -.
Genome annotation databases
CMR P0A252; STY0653.
Other
ProtoNet P0A252.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Antioxidant; Complete proteome; Oxidoreductase; Peroxidase; Redox-active center.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
INIT_MET   1     1        Removed (By similarity). 
CHAIN   2   187  186     Alkyl hydroperoxide reductase subunit C. PRO_0000135119
DOMAIN   2   157  156     Thioredoxin. 
ACT_SITE   47    47        Cysteine sulfenic acid (-SOH) intermediate (By similarity). 
DISULFID   47    47        Interchain (with C-166); in linked form (By similarity). 
DISULFID   166   166        Interchain (with C-47); in linked form (By similarity). 
Sequence information
Length: 187 AA [This is the length of the unprocessed precursor] Molecular weight: 20747 Da [This is the MW of the unprocessed precursor] CRC64: 83B251C74DE9860D [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSLINTKIKP FKNQAFKNGE FIEVTEKDTE GRWSVFFFYP ADFTFVCPTE LGDVADHYEE 

        70         80         90        100        110        120 
LQKLGVDVYS VSTDTHFTHK AWHSSSETIA KIKYAMIGDP TGALTRNFDN MREDEGLADR 

       130        140        150        160        170        180 
ATFVVDPQGI IQAIEVTAEG IGRDASDLLR KIKAAQYVAA HPGEVCPAKW KEGEATLAPS 


LDLVGKI 

P0A252 in FASTA format

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