[1]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. PubMed=3597432 [NCBI, ExPASy, EBI, Israel, Japan] Coles L.S., Robins A.J., Madley L.K., Wells J.R.E.; "Characterization of the chicken histone H1 gene complement. Generation of a complete set of vertebrate H1 protein sequences."; J. Biol. Chem. 262:9656-9663(1987).
[2]	STRUCTURE BY NMR OF 41-114. DOI=10.1021/bi00093a011; PubMed=8218199 [NCBI, ExPASy, EBI, Israel, Japan] Cerf C., Lippens G., Muyldermans S., Segers A., Ramakrishnan V., Wodak S.J., Hallenga K., Wyns L.; "Homo- and heteronuclear two-dimensional NMR studies of the globular domain of histone H1: sequential assignment and secondary structure."; Biochemistry 32:11345-11351(1993).

Comments

FUNCTION: Histones H1 are necessary for the condensation of nucleosome chains into higher order structures.
SUBCELLULAR LOCATION: Nucleus.
SIMILARITY: Belongs to the histone H1/H5 family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

M17019; AAA48789.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

B28456; B28456.

NP_001035733.1; -.

3D structure databases

PDB

1GHC; NMR; -; A=41-114.

[ExPASy / RCSB / EBI]

1GHC; -.

P08287; 41-114.

Ontologies

GO:0000786;	Cellular component: nucleosome (inferred from electronic annotation from InterPro).
GO:0005634;	Cellular component: nucleus (inferred from electronic annotation from InterPro).
GO:0003677;	Molecular function: DNA binding (inferred from electronic annotation from InterPro).
GO:0006334;	Biological process: nucleosome assembly (inferred from electronic annotation from InterPro).
QuickGo view.

Family and domain databases

InterPro

IPR005818; Histone_H1/H5.
IPR005819; Histone_H5.
IPR011991; Wing_hlx_DNA_bd.
Graphical view of domain structure.

Gene3D

G3DSA:1.10.10.10; Wing_hlx_DNA_bd; 1.

Pfam

PF00538; Linker_histone; 1.
Pfam graphical view of domain structure.

PRINTS

PR00624; HISTONEH5.

SMART

SM00526; H15; 1.
SMART graphical view of domain structure.

Genome annotation databases

Ensembl

ENSGALG00000011759; Gallus gallus. [Contig view]

GeneID

427892; -.

KEGG

gga:427892; -.

Phylogenomic databases

HOGENOM

P08287; -.

HOVERGEN

P08287; -.

Other

P08287; -.

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

3D-structure; Acetylation; Chromosomal protein; DNA-binding; Nucleus.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`INIT_MET`	`1 1`		`Removed.`
`CHAIN`	`2 225`	`224`	`Histone H1.11L.`	`PRO_0000195931`
`REGION`	`41 114`	`74`	`Globular.`
`MOD_RES`	`2 2`		`N-acetylserine (By similarity).`
`STRAND`	`41 43`	`3`
`HELIX`	`44 54`	`11`
`STRAND`	`56 59`	`4`
`HELIX`	`66 68`	`3`
`STRAND`	`69 74`	`6`
`STRAND`	`77 80`	`4`
`HELIX`	`81 87`	`7`
`TURN`	`88 90`	`3`
`HELIX`	`91 94`	`4`

Sequence information

Length: 225 AA [This is the length of the unprocessed precursor]

Molecular weight: 22528 Da [This is the MW of the unprocessed precursor]

CRC64: BFDA6897A7D5599F [This is a checksum on the sequence]

        10         20         30         40         50         60 
MSETAPAPAA EAAPAAAPAP AKAAAKKPKK AAGGAKARKP AGPSVTELIT KAVSASKERK 

        70         80         90        100        110        120 
GLSLAALKKA LAAGGYDVEK NNSRIKLGLK SLVSKGTLVQ TKGTGASGSF RLSKKPGEVK 

       130        140        150        160        170        180 
EKAPKKKASA AKPKKPAAKK PAAAAKKPKK AVAVKKSPKK AKKPAASATK KSAKSPKKVT 

       190        200        210        220 
KAVKPKKAVA AKSPAKAKAV KPKAAKPKAA KPKAAKAKKA AAKKK

P08287 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools