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UniProtKB/Swiss-Prot entry P08127

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NAHH_PSEPU
Primary accession number P08127
Secondary accession numbers None
Integrated into Swiss-Prot on August 1, 1988
Sequence was last modified on August 1, 1988 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 68)
Name and origin of the protein
Protein name Metapyrocatechase
Synonyms MPC
EC 1.13.11.2
CatO2ase
Catechol 2,3-dioxygenase
Gene name
Name: nahH
From
Pseudomonas putida [TaxID: 303] 
Encoded on Plasmid NAH7.
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=ATCC 17485 / DSM 50208 / Stanier 111 / JCM 6158 / Biotype A;
DOI=10.1007/BF00325689; PubMed=3481421 [NCBI, ExPASy, EBI, Israel, Japan]
Harayama S., Rekik M., Wasserfallen A., Bairoch A.;
"Evolutionary relationships between catabolic pathways for aromatics: conservation of gene order and nucleotide sequences of catechol oxidation genes of pWW0 and NAH7 plasmids.";
Mol. Gen. Genet. 210:241-247(1987).
[2]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=ATCC 17485 / DSM 50208 / Stanier 111 / JCM 6158 / Biotype A;
DOI=10.1016/0378-1119(87)90244-7; PubMed=3623105 [NCBI, ExPASy, EBI, Israel, Japan]
Ghosal D., You I.-S., Gunsalus I.C.;
"Nucleotide sequence and expression of gene nahH of plasmid NAH7 and homology with gene xylE of TOL pWWO.";
Gene 55:19-28(1987).
[3]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-8.
STRAIN=ATCC 17485 / DSM 50208 / Stanier 111 / JCM 6158 / Biotype A;
DOI=10.1021/bi00220a028; PubMed=1993181 [NCBI, ExPASy, EBI, Israel, Japan]
You I.-S., Ghosal D., Gunsalus I.C.;
"Nucleotide sequence analysis of the Pseudomonas putida PpG7 salicylate hydroxylase gene (nahG) and its 3'-flanking region.";
Biochemistry 30:1635-1641(1991).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
M17159; AAA98183.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
X06412; CAA29701.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
M60055; AAA25899.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR A27389; A27389.
RefSeq YP_534833.1; -.
3D structure databases
HSSP P06622; 1MPY. [HSSP ENTRY / PDB]
SMR P08127; 1-307.
ModBase P08127.
Ontologies
GO
GO:0018577; Molecular function: catechol 2,3-dioxygenase activity (inferred from electronic annotation from EC).
GO:0008198; Molecular function: ferrous iron binding (inferred from electronic annotation from InterPro).
GO:0019439; Biological process: aromatic compound catabolic process (inferred from electronic annotation from UniProtKB-KW).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR017624; Catechol_2-3_dOase.
IPR004360; Glyas_bleo-R_dOase.
IPR000486; Xdiol_dOase_1_2.
Graphical view of domain structure.
Pfam PF00903; Glyoxalase; 2.
Pfam graphical view of domain structure.
ProDom PD002334; Gly_diox; 2.
[Domain structure / List of seq. sharing at least 1 domain]
PROSITE PS00082; EXTRADIOL_DIOXYGENAS; 1.
Genome annotation databases
GeneID 3974217; -.
Other
ProtoNet P08127.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Aromatic hydrocarbons catabolism; Dioxygenase; Iron; Metal-binding; Oxidoreductase; Plasmid.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   307  307     Metapyrocatechase. PRO_0000085024
METAL   153   153        Iron (By similarity). 
METAL   214   214        Iron (By similarity). 
METAL   265   265        Iron (By similarity). 
Sequence information
Length: 307 AA [This is the length of the unprocessed precursor] Molecular weight: 34913 Da [This is the MW of the unprocessed precursor] CRC64: 140465CAA0CE7F4E [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MNKGVMRPGH VQLRVLDMGK ALEHYVELLG LIEMDRDDQG RVYLKAWTEV DKFSVVLREA 

        70         80         90        100        110        120 
DEPGMDFMGF KVVDEDSLNR LTDDLLNFGC LIENVAAGEL KGCGRRVRFQ APSGHHFELY 

       130        140        150        160        170        180 
ADKEYTGKWG VSEVNPEAWP RDLKGMAAVR FDHCLLYGDE LQATYELFTE VLGFYLAEQV 

       190        200        210        220        230        240 
VDADGIRLAQ FLSLSTKAHD VAFIHHAEKG KFHHASFFLD TWEDVLRAAD LISMTDTSID 

       250        260        270        280        290        300 
IGPTRHGLTQ GKTIYFFDPS GNRCEVFCGG NYNYPDHKPV TWLAKDVGKA IFYHDRVLNE 


RFMTVMT
P08127 in FASTA format

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