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[1]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 22-58, AND PYROGLUTAMATE FORMATION AT GLN-22.
STRAIN=VTT-D-80133;
DOI=10.1016/0378-1119(88)90541-0; PubMed=3384334 [NCBI, ExPASy, EBI, Israel, Japan]
Saloheimo M.,
Lehtovaara P.,
Penttilae M.,
Teeri T.T.,
Staahlberg J.,
Johansson G.,
Pettersson G.,
Clayssens M.,
Tomme P.,
Knowles J.K.C.;
"EGIII, a new endoglucanase from Trichoderma reesei: the characterization of both gene and enzyme.";
Gene 63:11-21(1988).
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[2]
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PROTEIN SEQUENCE OF 87-99.
PubMed=3356188 [NCBI, ExPASy, EBI, Israel, Japan]
Stahlberg J.,
Johansson G.,
Pettersson G.;
"A binding-site-deficient, catalytically active, core protein of endoglucanase III from the culture filtrate of Trichoderma reesei.";
Eur. J. Biochem. 173:179-183(1988).
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[3]
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ACTIVE SITE GLU-350.
DOI=10.1016/0014-5793(93)81202-B; PubMed=8093602 [NCBI, ExPASy, EBI, Israel, Japan]
Macarron R.,
van Beeumen J.,
Henrissat B.,
de la Mata I.,
Claeyssens M.;
"Identification of an essential glutamate residue in the active site of endoglucanase III from Trichoderma reesei.";
FEBS Lett. 316:137-140(1993).
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- FUNCTION: The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the dissaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
- CATALYTIC ACTIVITY: Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
- SIMILARITY: Contains 1 CBM1 (fungal-type carbohydrate-binding) domain.
- CAUTION: Was originally called endoglucanase EG-III.
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 418 AA [This is the length of the unprocessed precursor] |
Molecular weight: 44227 Da [This is the MW of the unprocessed precursor] |
CRC64: 26A492D55237A49B [This is a checksum on the sequence] |
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10 20 30 40 50 60
MNKSVAPLLL AASILYGGAV AQQTVWGQCG GIGWSGPTNC APGSACSTLN PYYAQCIPGA
70 80 90 100 110 120
TTITTSTRPP SGPTTTTRAT STSSSTPPTS SGVRFAGVNI AGFDFGCTTD GTCVTSKVYP
130 140 150 160 170 180
PLKNFTGSNN YPDGIGQMQH FVNEDGMTIF RLPVGWQYLV NNNLGGNLDS TSISKYDQLV
190 200 210 220 230 240
QGCLSLGAYC IVDIHNYARW NGGIIGQGGP TNAQFTSLWS QLASKYASQS RVWFGIMNEP
250 260 270 280 290 300
HDVNINTWAA TVQEVVTAIR NAGATSQFIS LPGNDWQSAG AFISDGSAAA LSQVTNPDGS
310 320 330 340 350 360
TTNLIFDVHK YLDSDNSGTH AECTTNNIDG AFSPLATWLR QNNRQAILTE TGGGNVQSCI
370 380 390 400 410
QDMCQQIQYL NQNSDVYLGY VGWGAGSFDS TYVLTETPTS SGNSWTDTSL VSSCLARK
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P07982 in FASTA format |
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