[1]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. STRAIN=FP-9 / Isolate HP-440; Skinner M.A.; Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
[2]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. PubMed=2177083 [NCBI, ExPASy, EBI, Israel, Japan] Binns M.M., Britton B.S., Mason C., Boursnell M.E.G.; "Analysis of the fowlpox virus genome region corresponding to the vaccinia virus D6 to A1 region: location of, and variation in, non-essential genes in poxviruses."; J. Gen. Virol. 71:2873-2881(1990).
[3]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. DOI=10.1128/JVI.74.8.3815-3831.2000; PubMed=10729156 [NCBI, ExPASy, EBI, Israel, Japan] Afonso C.L., Tulman E.R., Lu Z., Zsak L., Kutish G.F., Rock D.L.; "The genome of fowlpox virus."; J. Virol. 74:3815-3831(2000).

Comments

FUNCTION: Catalyzes the last reaction in the mRNA cap formation pathway.
CATALYTIC ACTIVITY: S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m₇G(5')pppR-RNA.
SUBUNIT: Heterodimer of a large and a small subunit.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AJ005163; CAA06402.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
AF198100; AAF44395.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

S42252; S42252.

RefSeq

NP_039014.1; -.

3D structure databases

ModBase

O72908.

Ontologies

GO:0004482;	Molecular function: mRNA (guanine-N7-)-methyltransferase activity (inferred from electronic annotation from InterPro).
GO:0006370;	Biological process: mRNA capping (inferred from electronic annotation from InterPro).
QuickGo view.

Family and domain databases

InterPro

IPR005009; Pox_mRNA-cap.
Graphical view of domain structure.

Pfam

PF03341; Pox_mRNA-cap; 1.
Pfam graphical view of domain structure.

ProDom

PD009934; Pox_mRNA-cap; 1.
[Domain structure / List of seq. sharing at least 1 domain]

Genome annotation databases

GeneID

1486599; -.

Other

ProtoNet

O72908.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Methyltransferase; mRNA capping; mRNA processing; S-adenosyl-L-methionine; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 289`	`289`		`mRNA-capping enzyme small subunit.`	`PRO_0000210139`

Sequence information

Length: 289 AA [This is the length of the unprocessed precursor]

Molecular weight: 33867 Da [This is the MW of the unprocessed precursor]

CRC64: ADCEFC32AA71B131 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MNTDRITAFI KNGISARMPF YDTLPDMDLV FGKNHLPSLE YGANYFLQLS KINDINRLST 

        70         80         90        100        110        120 
EMLSLYTHDL NKESDISKLF EPYNIKTIKS YGRSIQADAV VVDLRPSNSL YKNEHPYYKS 

       130        140        150        160        170        180 
NNYLKENNLY ICDYTMITFE IYRPIFELST EKTCIIKVPT LFGKTIVNAV RVYCSLFRYV 

       190        200        210        220        230        240 
KLYKLSADSW LKDSAIIVCQ QPHAANINKF ITYIRKVTKS QTWLDSNNVN FILIHDSVER 

       250        260        270        280 
VFIEKFLSFS YKIYESLYYV HSLLYSSMTS DLQSLDNEYQ KKLIKLLRG

O72908 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools