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UniProtKB/Swiss-Prot entry O66973

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NADB_AQUAE
Primary accession number O66973
Secondary accession numbers None
Integrated into Swiss-Prot on August 30, 2002
Sequence was last modified on August 1, 1998 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 51)
Name and origin of the protein
Protein name L-aspartate oxidase
Synonyms LASPO
EC 1.4.3.16
Quinolinate synthetase B
Gene name
Name: nadB
OrderedLocusNames: aq_777
From
Aquifex aeolicus [TaxID: 63363] [HAMAP proteome]
Taxonomy Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=VF5;
DOI=10.1038/32831; PubMed=9537320 [NCBI, ExPASy, EBI, Israel, Japan]
Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L., Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R., Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
"The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
Nature 392:353-358(1998).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE000657; AAC06932.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR B70368; B70368.
RefSeq NP_213534.1; -.
3D structure databases
HSSP P10902; 1CHU. [HSSP ENTRY / PDB]
ModBase O66973.
Enzyme and pathway databases
BioCyc AAEO224324:AQ_777-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from InterPro).
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0008734; Molecular function: L-aspartate oxidase activity (inferred from electronic annotation from InterPro).
GO:0009435; Biological process: NAD biosynthetic process (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR003953; FAD_bind2_N.
IPR013027; FAD_pyr_nucl-diS_OxRdtase.
IPR004112; Fum_Rdtase/Succ_DHase_flav_C.
IPR005288; NadB.
IPR001100; Pyr_nuc-diS_OxRdtase.
Graphical view of domain structure.
Pfam PF00890; FAD_binding_2; 1.
PF02910; Succ_DH_flav_C; 1.
Pfam graphical view of domain structure.
PRINTS PR00368; FADPNR.
PR00411; PNDRDTASEI.
TIGRFAMs TIGR00551; nadB; 1.
Genome annotation databases
GeneID 1193423; -.
GenomeReviews AE000657_GR; aq_777.
KEGG aae:aq_777; -.
NMPDR fig|224324.1.peg.549; -.
Phylogenomic databases
HOGENOM O66973; -.
Genome annotation databases
CMR O66973; aq_777.
Other
ProtoNet O66973.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; FAD; Flavoprotein; Oxidoreductase; Pyridine nucleotide biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   510  510     L-aspartate oxidase. PRO_0000184378
NP_BIND   20    34  15     FAD (Potential). 
ACT_SITE   234   234        By similarity. 
ACT_SITE   250   250        By similarity. 
Sequence information
Length: 510 AA [This is the length of the unprocessed precursor] Molecular weight: 57793 Da [This is the MW of the unprocessed precursor] CRC64: B6D5AD83438D0C42 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MNYFLRFDTS LLPEEEAKVL ICGSGIGGLA TAISLKELGI EPLILTRGIG NTYYSQGGIA 

        70         80         90        100        110        120 
AAVLPDDSPY LHYCDTLRAG RYLNHELHTK LLTYEGIFRI LDLERWGVDF DKKNGFYETT 

       130        140        150        160        170        180 
LEGGHSKPRV LKVKDYTGRE IYTKLLKKTE ELGIKILHGE LQEIIIEENG VQGVIYSEEG 

       190        200        210        220        230        240 
SLKFIRTPLL ILATGGAASM YYYTSNPKKV RGDAIGIAFR MGATVKNPEF VQFHPTVLKG 

       250        260        270        280        290        300 
TNLLISEAVR GEGAILVNDR GERFVNELLP RDEVARAIYN QIKRGREVYL DLRPVAQKGI 

       310        320        330        340        350        360 
KIEERFPTIY SFLRERGYDP YREPVPIIPA AHYYIGGIEV DDRGRTSIQG LYAVGECSCT 

       370        380        390        400        410        420 
GIHGANRLAS NSLLEGVVFG HRTAYQVYLD LKILKPSKVN FRSERAGSDK PNLGIEELKK 

       430        440        450        460        470        480 
LMWNYVGLER DEEGLTYVKK RILSVLSQAK HWEPTPQNRQ LYDILLVALC TVEGALMRKE 

       490        500        510 
SRGVHYRKDY PTEREVYRRD TIITRDLFEL
O66973 in FASTA format

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