NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=VF5;
DOI=10.1038/32831; PubMed=9537320 [NCBI, ExPASy, EBI, Israel, Japan]
Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L., Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R., Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
"The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
Nature 392:353-358(1998).

Comments

CATALYTIC ACTIVITY: Geranyl diphosphate + isopentenyl diphosphate = diphosphate + trans,trans-farnesyl diphosphate.
SUBCELLULAR LOCATION: Cytoplasm.
SIMILARITY: Belongs to the FPP/GGPP synthetase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AE000657; AAC06913.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

E70365; E70365.

RefSeq

NP_213513.1; -.

3D structure databases

ModBase

O66952.

Enzyme and pathway databases

BioCyc

AAEO224324:AQ_748-MON; -.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from UniProtKB-KW).
GO:0004337;	Molecular function: geranyltranstransferase activity (inferred from electronic annotation from EC).
GO:0008299;	Biological process: isoprenoid biosynthetic process (inferred from electronic annotation from InterPro).
QuickGo view.

Family and domain databases

InterPro

IPR000092; Polyprenyl_synt.
IPR017446; Polyprenyl_synth-rel.
IPR008949; Terpenoid_synth.
Graphical view of domain structure.

Gene3D

G3DSA:1.10.600.10; Terpenoid_synth; 1.

PANTHER

PTHR12001; Polyprenyl_synt; 1.

Pfam

PF00348; polyprenyl_synt; 1.
Pfam graphical view of domain structure.

PROSITE

PS00723; POLYPRENYL_SYNTHET_1; 1.
PS00444; POLYPRENYL_SYNTHET_2; 1.

Genome annotation databases

1193402; -.

AE000657_GR; aq_748.

aae:aq_748; -.

fig|224324.1.peg.528; -.

Phylogenomic databases

HOGENOM

O66952; -.

Genome annotation databases

CMR

O66952; aq_748.

Other

ProtoNet

O66952.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Cytoplasm; Isoprene biosynthesis; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 262`	`262`		`Geranyltranstransferase.`	`PRO_0000123984`

Sequence information

Length: 262 AA [This is the length of the unprocessed precursor]

Molecular weight: 30037 Da [This is the MW of the unprocessed precursor]

CRC64: 400592121D46C25E [This is a checksum on the sequence]

        10         20         30         40         50         60 
MERIETWKEK IEKRLNEILK PEGPEELIEA MKYYPLQKGK RIRPLFTVAV ASALGGNEDD 

        70         80         90        100        110        120 
AITVGSGIEL IHNYSLIHDD LPCMDNDVWR RGLPTCHIKF GEAMALLAGD ALLTYTFEVL 

       130        140        150        160        170        180 
SQRENYKTLS CEEILEINKI IAQKAGSNGM VGGQVLDIKG YEDLYEVSVK KTGALFEACF 

       190        200        210        220        230        240 
MCGAVVAKRR EKLKEMESIG RKVGLLFQMV DDYLDKDGFY EKLGECLKEE IKKLYEELKE 

       250        260 
KEIFKESQEL RYLLDLIYKR IT

O66952 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools