NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=B-P 26;
PubMed=9515931 [NCBI, ExPASy, EBI, Israel, Japan]
Shimizu N., Koyama T., Ogura K.;
"Molecular cloning, expression, and characterization of the genes encoding the two essential protein components of Micrococcus luteus B-P 26 hexaprenyl diphosphate synthase.";
J. Bacteriol. 180:1578-1581(1998).

Comments

CATALYTIC ACTIVITY: Geranyl diphosphate + isopentenyl diphosphate = diphosphate + trans,trans-farnesyl diphosphate.
SUBCELLULAR LOCATION: Cytoplasm (Potential).
SIMILARITY: Belongs to the FPP/GGPP synthetase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AB003187; BAA25265.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

3D structure databases

ModBase

O66126.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from UniProtKB-KW).
GO:0004337;	Molecular function: geranyltranstransferase activity (inferred from electronic annotation from EC).
GO:0008299;	Biological process: isoprenoid biosynthetic process (inferred from electronic annotation from InterPro).
QuickGo view.

Family and domain databases

InterPro

IPR000092; Polyprenyl_synt.
IPR017446; Polyprenyl_synth-rel.
IPR008949; Terpenoid_synth.
Graphical view of domain structure.

Gene3D

G3DSA:1.10.600.10; Terpenoid_synth; 1.

PANTHER

PTHR12001; Polyprenyl_synt; 1.

Pfam

PF00348; polyprenyl_synt; 1.
Pfam graphical view of domain structure.

PROSITE

PS00723; POLYPRENYL_SYNTHET_1; 1.
PS00444; POLYPRENYL_SYNTHET_2; 1.

Other

ProtoNet

O66126.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Cytoplasm; Isoprene biosynthesis; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 291`	`291`		`Geranyltranstransferase.`	`PRO_0000123991`

Sequence information

Length: 291 AA [This is the length of the unprocessed precursor]

Molecular weight: 32362 Da [This is the MW of the unprocessed precursor]

CRC64: 797125AB71E5674A [This is a checksum on the sequence]

        10         20         30         40         50         60 
MLQEKLTMNR DFLNLINESL LNKYHPAQSR LHEAINYSLS AGGKRIRPLL VLTTLDSLGG 

        70         80         90        100        110        120 
NAHDGLPFGI ALEMIHTYSL IHDDLPAMDN DDYRRGKLTN HKRFDEATAI LAGDALLTDA 

       130        140        150        160        170        180 
FQCILNTQLN AEIKLSLINL LSTASGSNGM VYGQMLDMQG EHKTLTLNEL ERIHIHKTGE 

       190        200        210        220        230        240 
LIRAAIVSAG IIMNFNDAQI EQLNIIGKNV GLMFQIKDDI LDVEGSFENI GKTVGSDLNN 

       250        260        270        280        290 
DKSTYVSLLG LEASKQLLND KLTETYDALK TLQPINDNLK TLITYIVERN K

O66126 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools