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UniProtKB/Swiss-Prot entry O58496


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name IORB_PYRHO
Primary accession number O58496
Secondary accession numbers None
Integrated into Swiss-Prot on May 30, 2000
Sequence was last modified on August 1, 1998 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 44)
Name and origin of the protein
Protein name Indolepyruvate oxidoreductase subunit iorB
Synonyms IOR
EC 1.2.7.8
Indolepyruvate ferredoxin oxidoreductase subunit beta
Gene name
Name: iorB
OrderedLocusNames: PH0764
From
Pyrococcus horikoshii [TaxID: 53953] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=OT3;
DOI=10.1093/dnares/5.2.55; PubMed=9679194 [NCBI, ExPASy, EBI, Israel, Japan]
Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S., Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K., Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T., Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
"Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
DNA Res. 5:55-76(1998).
Comments
  • FUNCTION: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates (By similarity).
  • CATALYTIC ACTIVITY: (Indol-3-yl)pyruvate + CoA + 2 oxidized ferredoxin = S-2-(indol-3-yl)acetyl-CoA + CO2 + 2 reduced ferredoxin + H+.
  • SUBUNIT: Heterodimer of the iorA and iorB subunits.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000001; BAA29855.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR E71124; E71124.
RefSeq NP_142701.1; -.
3D structure databases
ModBase O58496.
Ontologies
GO
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0043805; Molecular function: indolepyruvate ferredoxin oxidoreductase activity (inferred from electronic annotation from EC).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR017719; Indolepyruvate_Fd_OxRdtase_bsu.
IPR002869; Pyrv_Fd/Flavodoxin_OxRdtase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.920.10; Pyrv_Fd/Flavodoxin_OxRdtase; 1.
Pfam PF01558; POR; 1.
Pfam graphical view of domain structure.
Genome annotation databases
GeneID 1443090; -.
GenomeReviews BA000001_GR; PH0764.
KEGG pho:PH0764; -.
NMPDR fig|70601.1.peg.743; -.
Phylogenomic databases
HOGENOM O58496; -.
Genome annotation databases
CMR O58496; PH0764.
Other
ProtoNet O58496.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   202  202     Indolepyruvate oxidoreductase subunit iorB. PRO_0000099935
Sequence information
Length: 202 AA [This is the length of the unprocessed precursor] Molecular weight: 21810 Da [This is the MW of the unprocessed precursor] CRC64: E430872F6F4FF9EE [This is a checksum on the sequence]
        10         20         30         40         50         60 
MKEYNIVITG VGGQGILTAA NLLGWAALKA GYKVRVGEVH GMSQRFGSVI AYVRFGDDVY 

        70         80         90        100        110        120 
GAMVPEGKAD VILSFEPVEA LRYINYLKKG GLVFTNARPI PPVQVSMGLA TYPSLEEIKR 

       130        140        150        160        170        180 
IVEEEFNGKF LAFDAEKLAI EAGNVITTNV VLIGALTQTP GFPLSAEHVK EVIRLSVPPK 

       190        200 
AVDVNMKAFD LGVKAAKEML NL 

O58496 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
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BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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