ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry O58495

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name IORA_PYRHO
Primary accession number O58495
Secondary accession numbers None
Integrated into Swiss-Prot on May 30, 2000
Sequence was last modified on August 1, 1998 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 54)
Name and origin of the protein
Protein name Indolepyruvate oxidoreductase subunit iorA
Synonyms IOR
EC 1.2.7.8
Indolepyruvate ferredoxin oxidoreductase subunit alpha
Gene name
Name: iorA
OrderedLocusNames: PH0765
From
Pyrococcus horikoshii [TaxID: 53953] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=OT3;
DOI=10.1093/dnares/5.2.55; PubMed=9679194 [NCBI, ExPASy, EBI, Israel, Japan]
Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S., Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K., Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T., Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
"Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
DNA Res. 5:55-76(1998).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000001; BAA29856.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR F71124; F71124.
RefSeq NP_142702.1; -.
3D structure databases
HSSP O28604; 1JNR. [HSSP ENTRY / PDB]
ModBase O58495.
Ontologies
GO
GO:0051539; Molecular function: 4 iron, 4 sulfur cluster binding (inferred from electronic annotation from UniProtKB-KW).
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0043805; Molecular function: indolepyruvate ferredoxin oxidoreductase activity (inferred from electronic annotation from EC).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0030976; Molecular function: thiamin pyrophosphate binding (inferred from electronic annotation from InterPro).
GO:0022900; Biological process: electron transport chain (inferred from electronic annotation from UniProtKB-KW).
GO:0006810; Biological process: transport (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR001450; 4Fe4S_Fe_S_bd.
IPR017721; Indolepyruvate_Fd_OxRdtase_asu.
IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
IPR011766; TPP_enzyme_bd_C.
Graphical view of domain structure.
Pfam PF00037; Fer4; 2.
PF01855; POR_N; 1.
PF02775; TPP_enzyme_C; 1.
Pfam graphical view of domain structure.
PRINTS PR00353; 4FE4SFRDOXIN.
PROSITE PS00198; 4FE4S_FER_1; 1.
PS51379; 4FE4S_FER_2; 2.
PROSITE graphical view of domain structure (profiles).
Genome annotation databases
GeneID 1443091; -.
GenomeReviews BA000001_GR; PH0765.
KEGG pho:PH0765; -.
NMPDR fig|70601.1.peg.744; -.
Phylogenomic databases
HOGENOM O58495; -.
Genome annotation databases
CMR O58495; PH0765.
Other
ProtoNet O58495.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
4Fe-4S; Complete proteome; Electron transport; Iron; Iron-sulfur; Metal-binding; Oxidoreductase; Repeat; Transport.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   648  648     Indolepyruvate oxidoreductase subunit iorA. PRO_0000099929
DOMAIN   585   614  30     4Fe-4S ferredoxin-type 1. 
DOMAIN   616   645  30     4Fe-4S ferredoxin-type 2. 
METAL   625   625        Iron-sulfur (4Fe-4S) (Potential). 
METAL   628   628        Iron-sulfur (4Fe-4S) (Potential). 
METAL   631   631        Iron-sulfur (4Fe-4S) (Potential). 
METAL   635   635        Iron-sulfur (4Fe-4S) (Potential). 
Sequence information
Length: 648 AA [This is the length of the unprocessed precursor] Molecular weight: 71532 Da [This is the MW of the unprocessed precursor] CRC64: 75A843815FCE08B1 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MVKVTDIVLW DKPGEKVLLL GNQAIVRGAL EGNIGVYAAY PGTPSSEITD TMAMVAKKAG 

        70         80         90        100        110        120 
VYMEYSTNEK VAFETALSAS WAGLRAMTAM KHVGLNVAMD SFMTVSYMGI NGGLIVVVAD 

       130        140        150        160        170        180 
DPSMWSSQNE QDTRAIAKFA NIPVLEPSSV QEAKDMVKYA FEISEKYGQM VILRTTTRSS 

       190        200        210        220        230        240 
HMRGDVVLGE LPQEIKEGKR KFGNFKKNPE KYVDIPAFQR PKHPWLLETI EKFREEFNTS 

       250        260        270        280        290        300 
PFNWIEGPED AKVGIIAPGL SYAYVKEALA WLGIDNVKIL KLGTPFPVPY GLLEKFFNGL 

       310        320        330        340        350        360 
ERVLIVEELE PVVEEQVKVW AFDNNINIEI HGKDLVPRVY EMTTRRAVEA VAKFLGVETP 

       370        380        390        400        410        420 
INFQEIDEKY KKVQEMVPPR PPSLCPACPH RNTFFAIRKA ATPRAIFPSD IGCYTLGVLP 

       430        440        450        460        470        480 
PLKTVDTTIA MGGSIGVAHG LSIALNGALG EEQRKTGKEK KIIVATIGDS TFFHTGLPAL 

       490        500        510        520        530        540 
ANAIYNRSNV LIVVMDNMVT AMTGDQPNPG TGETPHGPGK RILIEEVARA MGADFVAVVD 

       550        560        570        580        590        600 
PYDIKETYET IKKALEVEGV SVVVSRRACA LYRIGQLRRE GKQWPIYQVN EEKCTGCKIC 

       610        620        630        640 
INAYGCPAIY WDAEKKKARV DPLMCWGCGG CAQVCPFGAF EKVREGEL
O58495 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by kr flag YPRC Korea Mirror sites: Australia Brazil Canada China Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!