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UniProtKB/Swiss-Prot entry O57765

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NADB_PYRHO
Primary accession number O57765
Secondary accession numbers None
Integrated into Swiss-Prot on August 30, 2002
Sequence was last modified on August 1, 1998 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 50)
Name and origin of the protein
Protein name L-aspartate oxidase
Synonyms LASPO
EC 1.4.3.16
Quinolinate synthetase B
Gene name
Name: nadB
OrderedLocusNames: PH0015
From
Pyrococcus horikoshii [TaxID: 53953] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=OT3;
DOI=10.1093/dnares/5.2.55; PubMed=9679194 [NCBI, ExPASy, EBI, Israel, Japan]
Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S., Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K., Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T., Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
"Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
DNA Res. 5:55-76(1998).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000001; BAA29083.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR D71219; D71219.
RefSeq NP_142038.1; -.
3D structure databases
HSSP P10902; 1CHU. [HSSP ENTRY / PDB]
ModBase O57765.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from InterPro).
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0008734; Molecular function: L-aspartate oxidase activity (inferred from electronic annotation from InterPro).
GO:0009435; Biological process: NAD biosynthetic process (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR003953; FAD_bind2_N.
IPR013027; FAD_pyr_nucl-diS_OxRdtase.
IPR004112; Fum_Rdtase/Succ_DHase_flav_C.
IPR005288; NadB.
IPR001100; Pyr_nuc-diS_OxRdtase.
Graphical view of domain structure.
Pfam PF00890; FAD_binding_2; 1.
PF02910; Succ_DH_flav_C; 1.
Pfam graphical view of domain structure.
PRINTS PR00368; FADPNR.
PR00411; PNDRDTASEI.
TIGRFAMs TIGR00551; nadB; 1.
Genome annotation databases
GeneID 1443917; -.
GenomeReviews BA000001_GR; PH0015.
KEGG pho:PH0015; -.
NMPDR fig|70601.1.peg.17; -.
Phylogenomic databases
HOGENOM O57765; -.
Genome annotation databases
CMR O57765; PH0015.
Other
ProtoNet O57765.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; FAD; Flavoprotein; Oxidoreductase; Pyridine nucleotide biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   464  464     L-aspartate oxidase. PRO_0000184410
NP_BIND   7    21  15     FAD (Potential). 
ACT_SITE   213   213        By similarity. 
ACT_SITE   230   230        By similarity. 
Sequence information
Length: 464 AA [This is the length of the unprocessed precursor] Molecular weight: 51296 Da [This is the MW of the unprocessed precursor] CRC64: 6D5504A7EFAD738D [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MMEMRVGIVG GGLAGLTAAI ALAEKGFDVS IIGPRSTDSN SYLAQAGIAL PLLEGDSIRI 

        70         80         90        100        110        120 
HVLDTIKAGK YINDEEIVWN VISKSSEAHD FLTSHGVTFT GNELEGGHSY PRIFTIKSET 

       130        140        150        160        170        180 
GKHIIPILEK HARELDVNFI RGFVEEIGIN NGKLAGVFLQ GELLKFDAVV IAAGGFSGLY 

       190        200        210        220        230        240 
RFTAGVKNNI GLLIGDVALK GVPLRDMEFV QFHPTGFIGK RTYLITEAVR GAGAKLVTGD 

       250        260        270        280        290        300 
GERFVNELET RDIVARAIYM KMLEGKGVFL DARGIENFKD RFPYIYSVLR GEGINPEKDL 

       310        320        330        340        350        360 
IPITPVAHYT IGGISVDAFY RTRIKGLYAI GESACNGFHG ANRLASNSLL ECVVSGLEVA 

       370        380        390        400        410        420 
RTISREKPKR EVNDAPYSFN ELGDVDSIRE VLWNHAGIVR DEWSLREGLR KLKEIEVDER 

       430        440        450        460 
LKLVAKAVII SALKREESRG AHYRKDYPFM RKEFEHSSFF YPNV
O57765 in FASTA format

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