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UniProtKB/Swiss-Prot entry O48604

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name HPPD_HORVU
Primary accession number O48604
Secondary accession numbers None
Integrated into Swiss-Prot on July 15, 1998
Sequence was last modified on June 1, 1998 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 53)
Name and origin of the protein
Protein name 4-hydroxyphenylpyruvate dioxygenase
Synonyms EC 1.13.11.27
4-hydroxyphenylpyruvic acid oxidase
HPPDase
4HPPD
HPD
Gene name None
From
Hordeum vulgare (Barley) [TaxID: 4513] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP clade; Pooideae; Triticeae; Hordeum.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=cv. Carina;
TISSUE=Meristem;
Krupinska K., Falk J.;
"cDNA sequence encoding a barley 4-hydroxyphenylpyruvate dioxygenase with enhanced expression in meristematic leaf tissue and during leaf senescence.";
Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AJ000693; CAA04245.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T04471; T04471.
3D structure databases
SMR O48604; 28-424.
ModBase O48604.
Organism-specific databases
Gramene O48604; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from UniProtKB-KW).
GO:0003868; Molecular function: 4-hydroxyphenylpyruvate dioxygenase activity (inferred from electronic annotation from InterPro).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0006559; Biological process: L-phenylalanine catabolic process (inferred from electronic annotation from UniProtKB-KW).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0006572; Biological process: tyrosine catabolic process (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR005956; 4OHPhenylPyrv_dOase.
IPR004360; Glyas_bleo-R_dOase.
Graphical view of domain structure.
PANTHER PTHR11959; HPP_dOase; 1.
Pfam PF00903; Glyoxalase; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF009283; HPP_dOase; 1.
TIGRFAMs TIGR01263; 4HPPD; 1.
Other
ProtoNet O48604.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cytoplasm; Dioxygenase; Iron; Metal-binding; Oxidoreductase; Phenylalanine catabolism; Tyrosine catabolism.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   434  434     4-hydroxyphenylpyruvate dioxygenase. PRO_0000088399
METAL   211   211        Iron (By similarity). 
METAL   293   293        Iron (By similarity). 
METAL   379   379        Iron (By similarity). 
Sequence information
Length: 434 AA [This is the length of the unprocessed precursor] Molecular weight: 46550 Da [This is the MW of the unprocessed precursor] CRC64: 42DE721182654A4C [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MPPTPTTPAA TGAAAAVTPE HARPHRMVRF NPRSDRFHTL SFHHVEFWCA DAASAAGRFA 

        70         80         90        100        110        120 
FALGAPLAAR SDLSTGNSAH ASQLLRSGSL AFLFTAPYAN GCDAATASLP SFSADAARRF 

       130        140        150        160        170        180 
SADHGIAVRS VALRVADAAE AFRASRRRGA RPAFAPVDLG RGFAFAEVEL YGDVVLRFVS 

       190        200        210        220        230        240 
HPDGTDVPFL PGFEGVTNPD AVDYGLTRFD HVVGNVPELA PAAAYIAGFT GFHEFAEFTA 

       250        260        270        280        290        300 
EDVGTTESGL NSVVLANNSE GVLLPLNEPV HGTKRRSQIQ TFLEHHGGPG VQHIAVASSD 

       310        320        330        340        350        360 
VLRTLRKMRA RSAMGGFDFL PPPLPKYYEG VRRLAGDVLS EAQIKECQEL GVLVDRDDQG 

       370        380        390        400        410        420 
VLLQIFTKPV GDRPTLFLEM IQRIGCMEKD ERGEEYQKGG CGGFGKGNFS ELFKSIEDYE 

       430 
KSLEAKQSAA VQGS
O48604 in FASTA format

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