ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry O43090


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name NDH2_SCHPO
Primary accession number O43090
Secondary accession numbers None
Integrated into Swiss-Prot on May 20, 2008
Sequence was last modified on June 1, 1998 (Sequence version 1)
Annotations were last modified on    December 16, 2008 (Entry version 46)
Name and origin of the protein
Protein name Probable NADH-ubiquinone oxidoreductase C947.15c, mitochondrial [Precursor]
Synonym EC 1.6.5.3
Gene name
ORFNames: SPBC947.15c
From
Schizosaccharomyces pombe (Fission yeast) [TaxID: 4896] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 38366 / 972;
DOI=10.1038/nature724; PubMed=11859360 [NCBI, ExPASy, EBI, Israel, Japan]
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
"The genome sequence of Schizosaccharomyces pombe.";
Nature 415:871-880(2002).
[2]
SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
DOI=10.1038/nbt1222; PubMed=16823372 [NCBI, ExPASy, EBI, Israel, Japan]
Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.;
"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.";
Nat. Biotechnol. 24:841-847(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CU329671; CAA17043.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T40767; T40767.
RefSeq NP_595261.1; -.
3D structure databases
ModBase O43090.
Organism-specific databases
GeneDB_Spombe SPBC947.15c; -.
Gene expression databases
ArrayExpress O43090; -.
Ontologies
GO
GO:0005739; Cellular component: mitochondrion (inferred from electronic annotation from UniProtKB-KW).
GO:0050660; Molecular function: FAD binding (inferred from electronic annotation from InterPro).
GO:0008137; Molecular function: NADH dehydrogenase (ubiquinone) activity (inferred from electronic annotation from EC).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR013027; FAD_pyr_nucl-diS_OxRdtase.
IPR001100; Pyr_nuc-diS_OxRdtase.
IPR001327; Pyr_OxRdtase_NAD_bd.
Graphical view of domain structure.
Pfam PF00070; Pyr_redox; 1.
PF07992; Pyr_redox_2; 1.
Pfam graphical view of domain structure.
PRINTS PR00368; FADPNR.
PR00411; PNDRDTASEI.
Genome annotation databases
GeneID 2540211; -.
KEGG spo:SPBC947.15c; -.
Other
ProtoNet O43090.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; FAD; Flavoprotein; Mitochondrion; NAD; Oxidoreductase; Transit peptide; Ubiquinone.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
TRANSIT   1    35  35     Mitochondrion (Potential). 
CHAIN   36   551  516     Probable NADH-ubiquinone oxidoreductase C947.15c, mitochondrial. PRO_0000337258
NP_BIND   92   122  31     FAD (By similarity). 
NP_BIND   255   291  37     NAD (By similarity). 
Sequence information
Length: 551 AA [This is the length of the unprocessed precursor] Molecular weight: 60781 Da [This is the MW of the unprocessed precursor] CRC64: C8CE3C56F88108AC [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSVSKARLQS VVRLSRTVPY SKTMVRSFHV SCAVKNSGNV PTPRNKSFFS RALEMAEVTS 

        70         80         90        100        110        120 
SLSMLGAVAL FQSLRRLNNS SPKGKSGVPK KNIVVLGSGW GAVAAIKNLD PSLYNITLVS 

       130        140        150        160        170        180 
PRDHFLFTPM LPSCTVGTLR LPSITEPIVA LFKGKIDPSN IHQAECTAID TSAKKVTIRG 

       190        200        210        220        230        240 
TTEANEGKEA VIPYDTLVFA IGAGNQTFGI QGVRDHGCFL KEAGDAKKVF NRIFEILEQV 

       250        260        270        280        290        300 
RFNKDLSPEE RARLLHITVV GGGPTGMEFA AEMQDFIDND VKDMFPELQK DIHVTLIEAA 

       310        320        330        340        350        360 
PGVLPMFTKS LITYTENLFK NLNIKIMTKT VVKDVNEKNL IVQKTNPDGS KAMQEIPYGM 

       370        380        390        400        410        420 
LVWAAGITAR PLTRTLMSSI PEQSGARKGL IVDEFFRVKG VPEMYAVGDC AFSGLPATAQ 

       430        440        450        460        470        480 
VANQQGAWLA KNLNVEGKKF ALHERIQALE KQLGEKEAPS QVAGLKQQVE QLKLEPFKYH 

       490        500        510        520        530        540 
HQGALAYVGD EKAIADLKLP FMKKMLPLQG IVGHTFWRLA YLNELISARS QFMVLIDWLK 

       550 
TRLFGRYDAK V 

O43090 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by kr flag YPRC Korea Mirror sites: Australia  Brazil  Canada  China  Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!