ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry O42890


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name AMOH1_SCHPO
Primary accession number O42890
Secondary accession numbers None
Integrated into Swiss-Prot on May 24, 2004
Sequence was last modified on June 1, 1998 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 48)
Name and origin of the protein
Protein name Putative primary amine oxidase 1
Synonyms EC 1.4.3.21
Copper amine oxidase 1
Gene name
ORFNames: SPBC1289.16c, SPBC8E4.06
From
Schizosaccharomyces pombe (Fission yeast) [TaxID: 4896] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 38366 / 972;
DOI=10.1038/nature724; PubMed=11859360 [NCBI, ExPASy, EBI, Israel, Japan]
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
"The genome sequence of Schizosaccharomyces pombe.";
Nature 415:871-880(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CU329671; CAB38696.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T39367; T39367.
T50376; T39171.
RefSeq NP_596841.2; -.
3D structure databases
HSSP P12807; 1A2V. [HSSP ENTRY / PDB]
ModBase O42890.
Enzyme and pathway databases
BioCyc SPOM-XXX-01:SPOM-XXX-01-004821-MON; -.
Organism-specific databases
GeneDB_Spombe SPBC1289.16c; -.
Gene expression databases
ArrayExpress O42890; -.
Ontologies
GO
GO:0005829; Cellular component: cytosol (inferred from direct assay from GeneDB_SPombe).
GO:0008131; Molecular function: amine oxidase activity (inferred from electronic annotation from InterPro).
GO:0005507; Molecular function: copper ion binding (inferred from electronic annotation from InterPro).
GO:0048038; Molecular function: quinone binding (inferred from electronic annotation from InterPro).
GO:0009308; Biological process: cellular amine metabolic process (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR000269; Cu_amine_oxidase.
IPR015798; Cu_amine_oxidase_C.
IPR015800; Cu_amine_oxidase_N2.
IPR015801; Cu_amine_oxidase_N2/3.
IPR015802; Cu_amine_oxidase_N3.
Graphical view of domain structure.
Gene3D G3DSA:3.10.450.40; CuNH_oxidase; 2.
G3DSA:2.70.98.20; Lyase_8_central; 1.
PANTHER PTHR10638; CuNH_oxidase; 1.
Pfam PF01179; Cu_amine_oxid; 1.
PF02727; Cu_amine_oxidN2; 1.
PF02728; Cu_amine_oxidN3; 1.
Pfam graphical view of domain structure.
PROSITE PS01164; COPPER_AMINE_OXID_1; 1.
PS01165; COPPER_AMINE_OXID_2; 1.
Genome annotation databases
GeneID 2539624; -.
KEGG spo:SPBC1289.16c; -.
Other
ProtoNet O42890.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Copper; Metal-binding; Oxidoreductase; TPQ.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   794  794     Putative primary amine oxidase 1. PRO_0000064107
ACT_SITE   309   309        Proton acceptor (By similarity). 
ACT_SITE   394   394        Schiff-base intermediate with substrate; via topaquinone (By similarity). 
METAL   445   445        Copper (By similarity). 
METAL   447   447        Copper (By similarity). 
METAL   604   604        Copper (By similarity). 
MOD_RES   394   394        2',4',5'-topaquinone (By similarity). 
Sequence information
Length: 794 AA [This is the length of the unprocessed precursor] Molecular weight: 90127 Da [This is the MW of the unprocessed precursor] CRC64: 81E0E1CAD73F54F9 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAEESKAAEY FDPLDPLSFN ELRYVVNLVR KSYPEKQISF DVVTLSEPHK EEYVHWRYSS 

        70         80         90        100        110        120 
AHEGIPDRRA YVIVLEKEVP GVFEGIVNLT TGKIEKWEHS VDTCPIITAD LLAITDEIVR 

       130        140        150        160        170        180 
NDANVIEQCK ICGVPESGLS NVYCDPWTIG YDERYGSGRR LQQALMYYKP GDSGHLRSIP 

       190        200        210        220        230        240 
LDFCPIIDVD QKKVIAIDIP KVRRPIPQDV NSDNNLKKLE QEMEAMKMLK PLRITQPEGV 

       250        260        270        280        290        300 
NFRIKGRYIE WQNFCFHIGF NYREGIVLSD VVFNEDGHLR PLFYRISLTE MAVPFGAKGH 

       310        320        330        340        350        360 
SHHRKHAYDL GEYGVGYRTN PLSFTCGCEG VIHYMDADFV NYRGEITTIK NAISIHEEDD 

       370        380        390        400        410        420 
GVLFKYSDLR DRNANISARS IKLVVSQVFT AANYEYLVYW IFRMDGVIEC EIRLTGILNT 

       430        440        450        460        470        480 
NAINEDEDLK GHGTQVYPKI SAENHEHLFC LRINPMLDGL RNSVATVDAL RDKNGTLVSK 

       490        500        510        520        530        540 
YIIPETVTEA ISNYDSSTGR TWDICNLNKL HPYSGKPVSY KLISRDTSPV LSQPGTTNSD 

       550        560        570        580        590        600 
CSGFAENNIY VTPYMDDQIF PTGDYAPQAS DDTPKGLSKW ISDDPNAQIK NTDIVVWHTF 

       610        620        630        640        650        660 
GMIHFPAPED FPIMPAESIH LFLQPRNFFK HNPALDTSSS VNSTSEATSP NTHHENLRDT 

       670        680        690        700        710        720 
SQKRESHSTP HDYEPHVSDK NDKSVEDKLH FVQKDESRPK EPVVDAAQKH EGRSETLAQP 

       730        740        750        760        770        780 
GQQNANQSEE KQGGQNGSNG GHHHHHHHHY ITGHVYGGYH KHSGSGGHLV DMMKNISDVT 

       790 
HDFAMGNFRY HKYD 

O42890 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by kr flag YPRC Korea Mirror sites: Australia  Brazil  Canada  China  Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!