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UniProtKB/Swiss-Prot entry O42231

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CP1A1_LIZAU
Primary accession number O42231
Secondary accession numbers None
Integrated into Swiss-Prot on May 30, 2000
Sequence was last modified on January 1, 1998 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 49)
Name and origin of the protein
Protein name Cytochrome P450 1A1
Synonyms EC 1.14.14.1
CYPIA1
Gene name
Name: cyp1a1
From
Liza aurata (Golden grey mullet) [TaxID: 48191] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei; Acanthomorpha; Acanthopterygii; Percomorpha; Mugilomorpha; Mugilidae; Liza.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Liver;
Cousinou M., Lopez-Barea J., Dorado G.;
Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AF022433; AAB70307.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
3D structure databases
HSSP P00179; 1DT6. [HSSP ENTRY / PDB]
ModBase O42231.
Ontologies
GO
GO:0005789; Cellular component: endoplasmic reticulum membrane (inferred from electronic annotation from UniProtKB-SubCell).
GO:0005792; Cellular component: microsome (inferred from electronic annotation from UniProtKB-KW).
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0020037; Molecular function: heme binding (inferred from electronic annotation from InterPro).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from InterPro).
GO:0050381; Molecular function: unspecific monooxygenase activity (inferred from electronic annotation from EC).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR001128; Cyt_P450.
IPR002401; Cyt_P450_E_grp-I.
IPR008066; Cyt_P450_E_grp-I_CYP1.
Graphical view of domain structure.
Gene3D G3DSA:1.10.630.10; Cyt_P450; 1.
PANTHER PTHR19383; Cyt_P450; 1.
PTHR19383:SF63; Cyt_P450_E_grp-I_CYP1; 1.
Pfam PF00067; p450; 1.
Pfam graphical view of domain structure.
PRINTS PR00463; EP450I.
PR01683; EP450ICYP1A.
PR00385; P450.
PROSITE PS00086; CYTOCHROME_P450; 1.
Phylogenomic databases
HOVERGEN O42231; -.
Other
ProtoNet O42231.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Endoplasmic reticulum; Heme; Iron; Membrane; Metal-binding; Microsome; Monooxygenase; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   521  521     Cytochrome P450 1A1. PRO_0000051638
METAL   463   463        Iron (heme axial ligand) (By similarity). 
Sequence information
Length: 521 AA [This is the length of the unprocessed precursor] Molecular weight: 59064 Da [This is the MW of the unprocessed precursor] CRC64: CD23195E40228DBE [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MALMILPFIG ALSVSESLVA LVTVCLVYLI IKSFQANIPE GLSRLPGPKP LPIIGNVLEV 

        70         80         90        100        110        120 
GSRPYLSLTE MSKRYGNVFQ IQIGMRPVVV LSGNETVRQA LIKQGDEFAG RPDLYSFRFI 

       130        140        150        160        170        180 
SEGKSLAFST DQAGVWRARR KLAYSALRSF STLEGTTPEY SCVLEEHISK EAEYLIKQLD 

       190        200        210        220        230        240 
TVMKADGSFD PFRYIVVSVA NVICGMCFGR RYDHHDRELL SLVNLSDEFG QVVGSGNPAD 

       250        260        270        280        290        300 
FIPILQYLPN KTMKKFVNIN DRFISFVQKI VSEHYATFNK DNIRDITDSL IDHCEDRKLD 

       310        320        330        340        350        360 
ENANVQMSDE KVVGIVNDLF GAGLDTISTA LSWSVMYLVA YPEIQERLYQ ELKENVGLDR 

       370        380        390        400        410        420 
TPVLSDRNNL PLLEAFILEI FRHSSFLPFT IPHCTTKDTS LNGYYIPKDT CVFINQWQIN 

       430        440        450        460        470        480 
HDPELWKEPS SFNPDRFLSA DGTEVNKVDG EKVMVFGLGK RRCIGEVIAR NEVYMFLAIL 

       490        500        510        520 
IQKLHFYNLP GEPLDMTPEY GLTMKHKRCH LRATVRVRSD H
O42231 in FASTA format

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