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UniProtKB/Swiss-Prot entry O37319


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NTP1_HAEPV
Primary accession number O37319
Secondary accession numbers None
Integrated into Swiss-Prot on May 30, 2000
Sequence was last modified on January 1, 1998 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 43)
Name and origin of the protein
Protein name Nucleoside triphosphatase I
Synonyms EC 3.6.1.15
Nucleoside triphosphate phosphohydrolase I
NPH I
Gene name
Name: NPH1
ORFNames: F1L
From
Heliothis armigera entomopoxvirus (HaEPV) [TaxID: 10290] 
Taxonomy Viruses; dsDNA viruses, no RNA stage; Poxviridae; Entomopoxvirinae; Betaentomopoxvirus.
Virus host Lepidoptera (butterflies and moths) [TaxID: 7088]
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=9400959 [NCBI, ExPASy, EBI, Israel, Japan]
Sriskantha A., Osborne R.J., Dall D.J.;
"Mapping of the Heliothis armigera entomopoxvirus (HaEPV) genome, and analysis of genes encoding the HaEPV spheroidin and nucleoside triphosphate phosphohydrolase I proteins.";
J. Gen. Virol. 78:3115-3123(1997).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AF019224; AAB96624.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
3D structure databases
ModBase O37319.
Ontologies
GO
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from InterPro).
GO:0003677; Molecular function: DNA binding (inferred from electronic annotation from InterPro).
GO:0004386; Molecular function: helicase activity (inferred from electronic annotation from InterPro).
GO:0006350; Biological process: transcription (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR014001; DEAD-like_N.
IPR001650; DNA/RNA_helicase_C.
IPR014021; Helicase_SF1/SF2_ATP-bd.
IPR013676; NPHI_C.
IPR000330; SNF2_N.
Graphical view of domain structure.
Pfam PF00271; Helicase_C; 1.
PF08469; NPHI_C; 1.
PF00176; SNF2_N; 1.
Pfam graphical view of domain structure.
SMART SM00487; DEXDc; 1.
SM00490; HELICc; 1.
SMART graphical view of domain structure.
PROSITE PS51192; HELICASE_ATP_BIND_1; 1.
PS51194; HELICASE_CTER; 1.
PROSITE graphical view of domain structure (profiles).
Other
ProtoNet O37319.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Hydrolase; Nucleotide-binding; Transcription.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   646  646     Nucleoside triphosphatase I. PRO_0000099102
DOMAIN   48   213  166     Helicase ATP-binding. 
DOMAIN   377   540  164     Helicase C-terminal. 
NP_BIND   61    68  8     ATP (By similarity). 
MOTIF   151   154  4     DEXH box. 
Sequence information
Length: 646 AA [This is the length of the unprocessed precursor] Molecular weight: 75763 Da [This is the MW of the unprocessed precursor] CRC64: AA1B63287F8B8034 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MFTLDSIVGA HINYALDKTA HLPETITNNV SNVEITLKDY QYFVSRVFIG LKNLNSMLLF 

        70         80         90        100        110        120 
WDTGMGKTLT AVYIIKHIKE LFPRWIILIF IKKSLYIDPW LNTIRAFAPD ISNNIIFVYY 

       130        140        150        160        170        180 
DSSSSLDKFV NIYRSIENSL NKKNRLLIII DEVHKLISRS VKKDNSERNF TPTYKKLIKL 

       190        200        210        220        230        240 
ANYEGNKILC MSATPIYNNI DEFNNLIGLL RPNVMTFKEE YIINGKLINF KEIRDTLLGL 

       250        260        270        280        290        300 
CSYKRLIEAD SFTETNYVEG YAKKNVIYHN IIMSEEQSKL FNLAEKYDYK TELGGLKTMR 

       310        320        330        340        350        360 
RLVSSFAFYD LKIKGDLNNI EYNDMIKRKL AEFSEFTKTI NFSNNFIEKF KRDDLKNDIL 

       370        380        390        400        410        420 
LEDINNYNIL YQYSCKYIEA CRIILNSRGK VLLFEPLVNF EGIASLKYYF NCFNITYVEY 

       430        440        450        460        470        480 
SSKTLKTRDI EISEYNNYEN NDGKNIKVCI FSYAGSEGIS FKCVNDIIIL DMPWNESELK 

       490        500        510        520        530        540 
QIMGRSIRLN SHNDLPLENR YVNVHFIISY TNNRKSVDKE ILDIIKDKQS KINVVFDLLK 

       550        560        570        580        590        600 
SISIESIHNI HKYIEPVESE TIFDTIRKTR MREMNISNVI VKIKLYPIMY CKDYDRATIL 

       610        620        630        640 
KGLLNKENNI IYNEDTAVAK LTIENNKPVF IIVDDNLIYI ADDYYE 

O37319 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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