[1]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. STRAIN=BL914; PubMed=8760926 [NCBI, ExPASy, EBI, Israel, Japan] Kirner S., Krauss S., Sury G., Lam S.T., Ligon J.M., van Pee K.-H.; "The non-haem chloroperoxidase from Pseudomonas fluorescens and its relationship to pyrrolnitrin biosynthesis."; Microbiology 142:2129-2135(1996).
[2]	X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS). STRAIN=BL914; DOI=10.1006/jmbi.1998.1802; PubMed=9642069 [NCBI, ExPASy, EBI, Israel, Japan] Hofmann B., Tolzer S., Pelletier I., Altenbuchner J., van Pee K.-H., Hecht H.-J.; "Structural investigation of the cofactor-free chloroperoxidases."; J. Mol. Biol. 279:889-900(1998).

Comments

CATALYTIC ACTIVITY: RH + Cl^- + H₂O₂ = RCl + 2 H₂O.
SUBUNIT: Homodimer.
SIMILARITY: Belongs to the bacterial non-heme bromo- and chloro-peroxidases family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AF031153; AAB86577.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

3D structure databases

PDB

1A8S; X-ray; 1.80 A; A=1-274.

[ExPASy / RCSB / EBI]

PDBsum

1A8S; -.

ModBase

O31158.

Protein family/group databases

PeroxiBase

5914; PfHalNPrx03_BL914.

Ontologies

GO:0031404;	Molecular function: chloride ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0016691;	Molecular function: chloride peroxidase activity (inferred from electronic annotation from EC).
GO:0055114;	Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

InterPro

IPR003089; AB_hydrolase.
IPR000073; AB_hydrolase_1.
IPR000639; Epox_hydrolase-like.
Graphical view of domain structure.

Pfam

PF00561; Abhydrolase_1; 1.
Pfam graphical view of domain structure.

PRINTS

PR00111; ABHYDROLASE.
PR00412; EPOXHYDRLASE.

Other

O31158; -.

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

3D-structure; Chloride; Oxidoreductase; Peroxidase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`INIT_MET`	`1 1`		`Removed.`
`CHAIN`	`2 274`	`273`	`Non-heme chloroperoxidase.`	`PRO_0000207060`
`ACT_SITE`	`95 95`		`By similarity.`
`ACT_SITE`	`225 225`		`By similarity.`
`ACT_SITE`	`254 254`		`By similarity.`
`STRAND`	`3 5`	`3`
`STRAND`	`11 18`	`8`
`STRAND`	`20 26`	`7`
`HELIX`	`33 36`	`4`
`HELIX`	`37 45`	`9`
`STRAND`	`49 53`	`5`
`HELIX`	`70 83`	`14`
`STRAND`	`88 94`	`7`
`HELIX`	`97 108`	`12`
`STRAND`	`113 120`	`8`
`HELIX`	`138 161`	`24`
`STRAND`	`164 166`	`3`
`HELIX`	`176 188`	`13`
`HELIX`	`191 203`	`13`
`HELIX`	`207 211`	`5`
`STRAND`	`217 222`	`6`
`STRAND`	`226 228`	`3`
`TURN`	`231 233`	`3`
`HELIX`	`234 240`	`7`
`STRAND`	`245 249`	`5`
`HELIX`	`256 259`	`4`
`HELIX`	`261 273`	`13`

Sequence information

Length: 274 AA [This is the length of the unprocessed precursor]

Molecular weight: 29651 Da [This is the MW of the unprocessed precursor]

CRC64: 00E2CF31A99E460F [This is a checksum on the sequence]

        10         20         30         40         50         60 
MTTFTTRDGT QIYYKDWGSG QPIVFSHGWP LNADSWESQM IFLAAQGYRV IAHDRRGHGR 

        70         80         90        100        110        120 
SSQPWSGNDM DTYADDLAQL IEHLDLRDAV LFGFSTGGGE VARYIGRHGT ARVAKAGLIS 

       130        140        150        160        170        180 
AVPPLMLKTE ANPGGLPMEV FDGIRQASLA DRSQLYKDLA SGPFFGFNQP GAKSSAGMVD 

       190        200        210        220        230        240 
WFWLQGMAAG HKNAYDCIKA FSETDFTEDL KKIDVPTLVV HGDADQVVPI EASGIASAAL 

       250        260        270 
VKGSTLKIYS GAPHGLTDTH KDQLNADLLA FIKG

O31158 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools