NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=9171435 [NCBI, ExPASy, EBI, Israel, Japan]
Kasberg T., Seibert V., Schlomann M., Reineke W.;
"Cloning, characterization, and sequence analysis of the clcE gene encoding the maleylacetate reductase of Pseudomonas sp. strain B13.";
J. Bacteriol. 179:3801-3803(1997).

Comments

CATALYTIC ACTIVITY: 3-oxoadipate + NAD(P)⁺ = 2-maleylacetate + NAD(P)H.
PATHWAY: Aromatic compound metabolism; 3-chlorocatechol degradation .
SIMILARITY: Belongs to the iron-containing alcohol dehydrogenase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AF019038; AAB71540.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

3D structure databases

ModBase

O30847.

Ontologies

GO:0018506;	Molecular function: maleylacetate reductase activity (inferred from electronic annotation from EC).
GO:0046872;	Molecular function: metal ion binding (inferred from electronic annotation from InterPro).
GO:0019439;	Biological process: aromatic compound catabolic process (inferred from electronic annotation from UniProtKB-KW).
GO:0055114;	Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

InterPro

IPR001670; Fe_AlcDHase.
Graphical view of domain structure.

Pfam

PF00465; Fe-ADH; 1.
Pfam graphical view of domain structure.

PROSITE

PS00913; ADH_IRON_1; FALSE_NEG.
PS00060; ADH_IRON_2; FALSE_NEG.

Other

ProtoNet

O30847.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Aromatic hydrocarbons catabolism; NAD; Oxidoreductase; Plasmid.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 352`	`352`		`Maleylacetate reductase.`	`PRO_0000087846`

Sequence information

Length: 352 AA [This is the length of the unprocessed precursor]

Molecular weight: 37769 Da [This is the MW of the unprocessed precursor]

CRC64: D4DBFDD69D990E79 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MNFIHDYRSP RVIFGPDSLA RLPQELERLG IDRALVLTTP EQAPLGRQVA EPVIGHVAAF 

        70         80         90        100        110        120 
YDGATMHVPA LVAEEACKIA RTSEANGVIA IGGGSTIGLA KIVALRTELP IVAVPTTYAG 

       130        140        150        160        170        180 
SEMTSIFGIT EGGVKKTGRD ARVMPRAVIY EPRLTLELPL SISVTSAINA IAHAVEGLYA 

       190        200        210        220        230        240 
PDATPLLTIM AQEGIAATVR AISRMYQSPR DLQARGDALY GAWLCASVLG NVSMALHHKL 

       250        260        270        280        290        300 
CHTLGGTLDL PHAQTHTVVL PHALAYNARA VPDAMRVLRI ALGHDDPPTA LYELARDNGA 

       310        320        330        340        350 
PVALRDLGMR EEDIEHVGDL ALQDRYPNPR ELDRDALLAL LRDAYHGRPP SA

O30847 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools