NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=W70;
PubMed=9457858 [NCBI, ExPASy, EBI, Israel, Japan]
Janes B.K., Bender R.A.;
"Alanine catabolism in Klebsiella aerogenes: molecular characterization of the dadAB operon and its regulation by the nitrogen assimilation control protein.";
J. Bacteriol. 180:563-570(1998).

Comments

FUNCTION: Oxidative deamination of D-amino acids.
CATALYTIC ACTIVITY: A D-amino acid + H₂O + acceptor = a 2-oxo acid + NH₃ + reduced acceptor.
COFACTOR: FAD (By similarity).
PATHWAY: Amino-acid degradation; D-alanine degradation; NH(3) and pyruvate from D-alanine: step 1/1 .
SUBUNIT: Heterodimer of a small and a large subunit (By similarity).
INDUCTION: By alanine; slightly repressed by glucose.
SIMILARITY: Belongs to the dadA oxidoreductase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AF016253; AAC38139.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

3D structure databases

ModBase

O30745.

Ontologies

GO:0008718;	Molecular function: D-amino-acid dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0006524;	Biological process: alanine catabolic process (inferred from electronic annotation from HAMAP).
GO:0055114;	Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

HAMAP

MF_01202; -; 1.
PBIL [Tree]

InterPro

IPR006076; FAD-dep_OxRdtase.
Graphical view of domain structure.

Pfam

PF01266; DAO; 1.
Pfam graphical view of domain structure.

ProDom

PD000139; FAD_pyr_redox; 1.
[Domain structure / List of seq. sharing at least 1 domain]

Other

ProtoNet

O30745.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

FAD; Flavoprotein; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 432`	`432`	`D-amino acid dehydrogenase small subunit.`	`PRO_0000166134`
`NP_BIND`	`3 17`	`15`	`FAD (Potential).`

Sequence information

Length: 432 AA [This is the length of the unprocessed precursor]

Molecular weight: 47251 Da [This is the MW of the unprocessed precursor]

CRC64: 096986F47BDB4DD6 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MRVVILGSGV FGVASAWYLS QAGHDVTVID RQPGPAEETS AANAGQISPG YAAPWAAPGV 

        70         80         90        100        110        120 
PLKAIKWMFQ RHAPLAIGLD GTSFQLKWMW QMLRNCDTRH YMENKGRMVR LAEYSRDCLK 

       130        140        150        160        170        180 
ALRDTTGIQY EGRQGGTLQL FRTAKQYENA TRDIAVLEDA GVPYQLLEAK RLAEVEPALA 

       190        200        210        220        230        240 
EVSHKLTGGL RLPNDETGDC QLFTTRLAAM ADQAGVTFRF NTAVDALLHE GDRIAGVKCG 

       250        260        270        280        290        300 
MRIIKGDAYV MAFGSYSTAM LKGLVDIPVY PLKGYSLTIP IAQEDGAPVS TILDVTYTIA 

       310        320        330        340        350        360 
ITRFDQRIRV GGMAEIVGFN KTLLQPRRET LEMVVRDLFP RGGHVEQATF WTGLRPMTPD 

       370        380        390        400        410        420 
GTPVVGRTAY KNLWLNTGHG TLGWTMACGS GQLISDLISG RTPAIPYDDL AVARYSPGFT 

       430 
PARPQHLHGA HN

O30745 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools