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UniProtKB/Swiss-Prot entry O24913


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MQO_HELPY
Primary accession number O24913
Secondary accession numbers None
Integrated into Swiss-Prot on May 30, 2000
Sequence was last modified on January 1, 1998 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 53)
Name and origin of the protein
Protein name Malate:quinone oxidoreductase
Synonyms EC 1.1.99.16
Malate dehydrogenase [acceptor]
MQO
Gene name
Name: mqo
OrderedLocusNames: HP_0086
From
Helicobacter pylori (Campylobacter pylori) [TaxID: 210] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; Helicobacteraceae; Helicobacter.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 700392 / 26695;
DOI=10.1038/41483; PubMed=9252185 [NCBI, ExPASy, EBI, Israel, Japan]
Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G., Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A., Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N., Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., Glodek A., McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E., Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D., Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S., Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.;
"The complete genome sequence of the gastric pathogen Helicobacter pylori.";
Nature 388:539-547(1997).
[2]
CHARACTERIZATION.
STRAIN=ATCC 49503 / 60190;
DOI=10.1128/JB.182.11.3204-3209.2000; PubMed=10809701 [NCBI, ExPASy, EBI, Israel, Japan]
Kather B., Stingl K., van der Rest M.E., Altendorf K., Molenaar D.;
"Another unusual type of citric acid cycle enzyme in Helicobacter pylori: the malate:quinone oxidoreductase.";
J. Bacteriol. 182:3204-3209(2000).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE000511; AAD07155.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR F64530; F64530.
RefSeq NP_206886.1; -.
3D structure databases
ModBase O24913.
Enzyme and pathway databases
BioCyc MetaCyc:HP0086-MON; -.
Ontologies
GO
GO:0005886; Cellular component: plasma membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0008924; Molecular function: malate dehydrogenase (acceptor) activity (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0006099; Biological process: tricarboxylic acid cycle (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00212; -; 1.
PBIL [Tree]
InterPro IPR006076; FAD-dep_OxRdtase.
Graphical view of domain structure.
Pfam PF01266; DAO; 1.
Pfam graphical view of domain structure.
Genome annotation databases
GeneID 899112; -.
GenomeReviews AE000511_GR; HP_0086.
KEGG hpy:HP0086; -.
NMPDR fig|85962.1.peg.84; -.
TIGR HP_0086; -.
Phylogenomic databases
HOGENOM O24913; -.
Other
ProtoNet O24913.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cell membrane; Complete proteome; FAD; Flavoprotein; Membrane; Oxidoreductase; Tricarboxylic acid cycle.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   450  450     Malate:quinone oxidoreductase. PRO_0000128717
Sequence information
Length: 450 AA [This is the length of the unprocessed precursor] Molecular weight: 50713 Da [This is the MW of the unprocessed precursor] CRC64: 5435E75D22E6E40B [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSMEFDAVII GGGVSGCATF YTLSEYSSLK RVAIVEKCSK LAQISSSAKA NSQTIHDGSI 

        70         80         90        100        110        120 
ETNYTPEKAK KVRLSAYKTR QYALNKGLQN EVIFETQKMA IGVGDEECEF MKKRYESFKE 

       130        140        150        160        170        180 
IFVGLEEFDK QKIKELEPNV ILGANGIDRH ENIIGHGYRK DWSTMNFAKL SENFVEEALK 

       190        200        210        220        230        240 
LKPNNQVFLN FKVKKIEKRN DTYAVISEDA EEVYAKFVLV NAGSYALPLA QSMGYGLDLG 

       250        260        270        280        290        300 
CLPVAGSFYF VPDLLRGKVY TVQNPKLPFA AVHGDPDAVI KGKTRIGPTA LTMPKLERNK 

       310        320        330        340        350        360 
CWLKGISLEL LKMDLNKDVF KIAFDLMSDK EIRNYVFKNM VFELPIIGKR KFLKDAQKII 

       370        380        390        400        410        420 
PSLSLEDLEY AHGFGEVRPQ VLDRTKRKLE LGEKKICTHK GITFNMTPSP GATSCLQNAL 

       430        440        450 
VDSQEIAAYL GESFELERFY KDLSPEELEN 

O24913 in FASTA format

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