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UniProtKB/Swiss-Prot entry O14400


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GPDM_SCHPO
Primary accession number O14400
Secondary accession numbers None
Integrated into Swiss-Prot on July 15, 1999
Sequence was last modified on January 1, 1998 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 61)
Name and origin of the protein
Protein name Glycerol-3-phosphate dehydrogenase, mitochondrial [Precursor]
Synonyms GPDH-M
GPD-M
EC 1.1.99.5
Gene name
Name: gut2
ORFNames: SPCC1223.03c
From
Schizosaccharomyces pombe (Fission yeast) [TaxID: 4896] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Hansen K.;
Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases.
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 38366 / 972;
DOI=10.1038/nature724; PubMed=11859360 [NCBI, ExPASy, EBI, Israel, Japan]
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
"The genome sequence of Schizosaccharomyces pombe.";
Nature 415:871-880(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
Y14993; CAA75227.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
CU329672; CAA20872.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T40863; T40863.
RefSeq NP_588348.1; -.
3D structure databases
ModBase O14400.
Enzyme and pathway databases
BioCyc SPOM-XXX-01:SPOM-XXX-01-000268-MON; -.
Organism-specific databases
GeneDB_Spombe SPCC1223.03c; -.
Gene expression databases
ArrayExpress O14400; -.
Ontologies
GO
GO:0009331; Cellular component: glycerol-3-phosphate dehydrogenase complex (inferred from electronic annotation from InterPro).
GO:0005739; Cellular component: mitochondrion (inferred from electronic annotation from UniProtKB-KW).
GO:0004368; Molecular function: glycerol-3-phosphate dehydrogenase activity (inferred from electronic annotation from InterPro).
GO:0033554; Biological process: cellular response to stress (inferred from expression pattern from GeneDB_SPombe).
GO:0006072; Biological process: glycerol-3-phosphate metabolic process (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR000447; FAD-dep_Gly3P_DHase.
IPR006076; FAD-dep_OxRdtase.
Graphical view of domain structure.
Pfam PF01266; DAO; 1.
Pfam graphical view of domain structure.
PRINTS PR01001; FADG3PDH.
PROSITE PS00977; FAD_G3PDH_1; 1.
PS00978; FAD_G3PDH_2; 1.
Genome annotation databases
GeneID 2539217; -.
KEGG spo:SPCC1223.03c; -.
NMPDR fig|4896.1.peg.686; -.
Other
ProtoNet O14400.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; FAD; Flavoprotein; Mitochondrion; Oxidoreductase; Transit peptide.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
TRANSIT   1     ?        Mitochondrion (Potential). 
CHAIN   ?   649        Glycerol-3-phosphate dehydrogenase, mitochondrial. PRO_0000010433
NP_BIND   69    97  29     FAD (Potential). 
Sequence information
Length: 649 AA [This is the length of the unprocessed precursor] Molecular weight: 71873 Da [This is the MW of the unprocessed precursor] CRC64: 65702D1FDE831E6A [This is a checksum on the sequence]
        10         20         30         40         50         60 
MFSIFKRRSV QAALAASGLV GGAVFYSDFI KRPAPSHFNP QFTPFTKSLA PPPSRETLLK 

        70         80         90        100        110        120 
NVEDISKFDV LIIGGGATGT GVAVDASTRG LNVCLLEKTD FASETSSKST KMAHGGVRYL 

       130        140        150        160        170        180 
EKAVFQLSKA QLDLVIEALN ERANMLRTAP HLCTVLPIMI PVYKWWQVPY FFVGCKIYDW 

       190        200        210        220        230        240 
VAGSKNLRAS TIFSKETTVA IAPMLDDSNL KASCVYHDGS FNDTRMNTTL AVTAIDNGAT 

       250        260        270        280        290        300 
VLNYMEVKKL LKSKDNKLEG VLAIDRETGK EYQIKATSVV NATGPFSDKI LEMDADPQGE 

       310        320        330        340        350        360 
PPKTAQFPRM VVPSAGVHVV LPEYYCPPNI GILDPSTSDN RVMFFLPWQG KVIAGTTDKP 

       370        380        390        400        410        420 
LSSVPTNPTP SEDDIQLILK ELQKYLVFPV DREDVLSAWC GIRPLVRDPS TVPPGTDPTT 

       430        440        450        460        470        480 
GETQGLVRSH FIFKSDTGLL TISGGKWTTY REMAEETVNE LIKDHDFGKA LKPCQTKKLI 

       490        500        510        520        530        540 
LVGGENYYKN YSARLIHEYH IPLRLAKHLS HNYGSRAPLI LELYSKTDFN KLPVTLADKE 

       550        560        570        580        590        600 
VFAPSSDASS DKSVSYASFD EPFTVAELKY SIKYEYTRTP TDFLARRTRL AFLDARQALQ 

       610        620        630        640 
AVAGVTHVMK EEFGWDDATT DKLAQEARDY IGGMGVSSDR FDVKQFEVK 

O14400 in FASTA format

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View entry in raw text format (no links)
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