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UniProtKB/Swiss-Prot entry O14313


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PMP20_SCHPO
Primary accession number O14313
Secondary accession number O74877
Integrated into Swiss-Prot on December 15, 1998
Sequence was last modified on April 27, 2001 (Sequence version 2)
Annotations were last modified on    November 25, 2008 (Entry version 55)
Name and origin of the protein
Protein name Putative peroxiredoxin pmp20
Synonyms EC 1.11.1.15
Thioredoxin reductase
Peroxisomal membrane protein pmp20
Gene name
Name: pmp20
ORFNames: SPCC330.06c
From
Schizosaccharomyces pombe (Fission yeast) [TaxID: 4896] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=ATCC 38366 / 972;
Lenaers G., Perret E., Delpech B., Picard A., Caput D.;
Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases.
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 38366 / 972;
DOI=10.1038/nature724; PubMed=11859360 [NCBI, ExPASy, EBI, Israel, Japan]
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
"The genome sequence of Schizosaccharomyces pombe.";
Nature 415:871-880(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AJ002536; CAA05528.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
CU329672; CAA20911.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T41316; T41316.
RefSeq NP_587706.1; -.
3D structure databases
HSSP P44758; 1NM3. [HSSP ENTRY / PDB]
ModBase O14313.
Enzyme and pathway databases
BioCyc SPOM-XXX-01:SPOM-XXX-01-002075-MON; -.
Organism-specific databases
GeneDB_Spombe SPCC330.06c; -.
Gene expression databases
ArrayExpress O14313; -.
Ontologies
GO
GO:0005829; Cellular component: cytosol (inferred from direct assay from GeneDB_SPombe).
GO:0005634; Cellular component: nucleus (inferred from direct assay from GeneDB_SPombe).
GO:0005777; Cellular component: peroxisome (inferred from electronic annotation from UniProtKB-KW).
GO:0051920; Molecular function: peroxiredoxin activity (inferred from electronic annotation from EC).
GO:0045454; Biological process: cell redox homeostasis (inferred from electronic annotation from InterPro).
GO:0033554; Biological process: cellular response to stress (inferred from expression pattern from GeneDB_SPombe).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR013740; Redoxin.
IPR012335; Thioredoxin_fold.
Graphical view of domain structure.
Gene3D G3DSA:3.40.30.10; Thioredoxin_fold; 1.
Pfam PF08534; Redoxin; 1.
Pfam graphical view of domain structure.
PROSITE PS51352; THIOREDOXIN_2; 1.
PROSITE graphical view of domain structure (profiles).
Genome annotation databases
GeneID 2538981; -.
KEGG spo:SPCC330.06c; -.
NMPDR fig|4896.1.peg.44; -.
Other
ProtoNet O14313.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Oxidoreductase; Peroxidase; Peroxisome; Redox-active center.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   156  156     Putative peroxiredoxin pmp20. PRO_0000056609
DOMAIN   2   156  155     Thioredoxin. 
MOTIF   154   156  3     Microbody targeting signal (By similarity). 
CONFLICT   20    20        E -> K (in Ref. 1; CAA05528). 
Sequence information
Length: 156 AA [This is the length of the unprocessed precursor] Molecular weight: 16675 Da [This is the MW of the unprocessed precursor] CRC64: 234DC024251F41D2 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MVAVGSTLPK VTLWENKPEE VVEFPSQGKF IIVGVPGAFT PPCSSQVPGY IANEKQFAAK 

        70         80         90        100        110        120 
GISGIYVVAV NDVFVTKAWK KSFDGGEQSG VHFVADWNGE FTKAFDAGFD ASGLLGPLRS 

       130        140        150 
KRYAAVVENG KVVKVFIENE VTDVDISSAD KVLSSL 

O14313 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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