[1]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. STRAIN=KOD1; DOI=10.1007/s004380050436; PubMed=9180697 [NCBI, ExPASy, EBI, Israel, Japan] Siddiqui M.A., Fujiwara S., Imanaka T.; "Indolepyruvate ferredoxin oxidoreductase from Pyrococcus sp. KOD1 possesses a mosaic structure showing features of various oxidoreductases."; Mol. Gen. Genet. 254:433-439(1997).
[2]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. STRAIN=KOD1; DOI=10.1101/gr.3003105; PubMed=15710748 [NCBI, ExPASy, EBI, Israel, Japan] Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.; "Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes."; Genome Res. 15:352-363(2005).

Comments

FUNCTION: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
CATALYTIC ACTIVITY: (Indol-3-yl)pyruvate + CoA + 2 oxidized ferredoxin = S-2-(indol-3-yl)acetyl-CoA + CO₂ + 2 reduced ferredoxin + H⁺.
BIOPHYSICOCHEMICAL PROPERTIES:

Temperature dependence: Optimum temperature is 70 degrees Celsius;
SUBUNIT: Heterodimer of the iorA and iorB subunits.
SEQUENCE CAUTION:
- Sequence=BAA20529.1; Type=Frameshift; Positions=132, 148, 167, 176, 189;

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

D86221; BAA20529.1; ALT_FRAME; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
AP006878; BAD84324.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_182548.1; -.

3D structure databases

ModBase

O07836.

Enzyme and pathway databases

BioCyc

TKOD69014:TK0135-MON; -.

Ontologies

GO:0009055;	Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0043805;	Molecular function: indolepyruvate ferredoxin oxidoreductase activity (inferred from electronic annotation from EC).
GO:0055114;	Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

InterPro

IPR017719; Indolepyruvate_Fd_OxRdtase_bsu.
IPR002869; Pyrv_Fd/Flavodoxin_OxRdtase.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.920.10; Pyrv_Fd/Flavodoxin_OxRdtase; 1.

Pfam

PF01558; POR; 1.
Pfam graphical view of domain structure.

Genome annotation databases

3235681; -.

AP006878_GR; TK0135.

tko:TK0135; -.

fig|69014.3.peg.303; -.

Phylogenomic databases

HOGENOM

O07836; -.

Genome annotation databases

CMR

O07836; TK0135.

Other

ProtoNet

O07836.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 202`	`202`	`Indolepyruvate oxidoreductase subunit iorB.`	`PRO_0000099936`
`CONFLICT`	`158 158`		`Q -> K (in Ref. 1; BAA20529).`
`CONFLICT`	`188 188`		`A -> S (in Ref. 1; BAA20529).`

Sequence information

Length: 202 AA [This is the length of the unprocessed precursor]

Molecular weight: 21886 Da [This is the MW of the unprocessed precursor]

CRC64: 2BCB29E499855B43 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKEYNIVITG VGGQGILTAA NLLGWAALRA GYKVRVGEVH GMSQRFGSVI AYVRFGEDVY 

        70         80         90        100        110        120 
GAMVPEGKAD VILSFEPVEA LRYINYLKKG GLVFTNARPI PPVQVSMGLA TYPTLDEMKK 

       130        140        150        160        170        180 
IVEEDFGGKF MAFDAEKLAM EAGNIVTTNV VLIGALSQTP GFPLSEEQIK EVIRISVPPK 

       190        200 
TIDVNMRAFE LGVKAAKEML GL

O07836 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools