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UniProtKB/Swiss-Prot entry O04922


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GPX2_ARATH
Primary accession number O04922
Secondary accession numbers None
Integrated into Swiss-Prot on March 27, 2002
Sequence was last modified on July 1, 1997 (Sequence version 1)
Annotations were last modified on    December 16, 2008 (Entry version 63)
Name and origin of the protein
Protein name Probable glutathione peroxidase 2
Synonym EC 1.11.1.9
Gene name
Name: GPX2
OrderedLocusNames: At2g31570
ORFNames: T9H9.9
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=cv. Columbia;
Turano F.J., Caldwell C.R., McMahon M.;
"Glutathione peroxidase cDNA from Arabidopsis.";
Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases.
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/45471; PubMed=10617197 [NCBI, ExPASy, EBI, Israel, Japan]
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
Nature 402:761-768(1999).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
DOI=10.1126/science.1088305; PubMed=14593172 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis genome.";
Science 302:842-846(2003).
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.;
"Full-length cDNA from Arabidopsis thaliana.";
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
[5]
GENE FAMILY, NOMENCLATURE, TISSUE SPECIFICITY, AND INDUCTION.
DOI=10.1046/j.1365-313X.2003.01901.x; PubMed=14617062 [NCBI, ExPASy, EBI, Israel, Japan]
Rodriguez Milla M.A., Maurer A., Rodriguez Huete A., Gustafson J.P.;
"Glutathione peroxidase genes in Arabidopsis are ubiquitous and regulated by abiotic stresses through diverse signaling pathways.";
Plant J. 36:602-615(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U94495; AAB52725.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AC007071; AAD24836.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY058187; AAL25600.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY044330; AAK73271.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY098982; AAM19992.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY086518; AAM63517.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR D84722; D84722.
RefSeq NP_180715.1; -.
UniGene At.10210
3D structure databases
HSSP P00435; 1GP1. [HSSP ENTRY / PDB]
ModBase O04922.
Protein family/group databases
PeroxiBase 2500; AtGPx02.
Organism-specific databases
GeneFarm 2049; 163.
TAIR At2g31570; -.
Gene expression databases
ArrayExpress O04922; -.
GermOnline AT2G31570; Arabidopsis thaliana.
Ontologies
GO
GO:0005829; Cellular component: cytosol (non-traceable author statement from TAIR).
GO:0004602; Molecular function: glutathione peroxidase activity (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0006979; Biological process: response to oxidative stress (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR000889; Glut_peroxidase.
IPR012335; Thioredoxin_fold.
Graphical view of domain structure.
Gene3D G3DSA:3.40.30.10; Thioredoxin_fold; 1.
PANTHER PTHR11592; Glut_peroxidase; 1.
Pfam PF00255; GSHPx; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000303; Glutathion_perox; 1.
PRINTS PR01011; GLUTPROXDASE.
PROSITE PS00460; GLUTATHIONE_PEROXID_1; 1.
PS00763; GLUTATHIONE_PEROXID_2; 1.
PS51355; GLUTATHIONE_PEROXID_3; 1.
PROSITE graphical view of domain structure (profiles).
Proteomics databases
PRIDE O04922; -.
Genome annotation databases
GeneID 817715; -.
GenomeReviews CT485783_GR; AT2G31570.
KEGG ath:AT2G31570; -.
NMPDR fig|3702.1.peg.10216; -.
Other
ProtoNet O04922.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Oxidoreductase; Peroxidase; Stress response.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
CHAIN   1   169  169     Probable glutathione peroxidase 2. PRO_0000066637
ACT_SITE   41    41        By similarity. 
Sequence information
Length: 169 AA [This is the length of the unprocessed precursor] Molecular weight: 18945 Da [This is the MW of the unprocessed precursor] CRC64: 23930B83A0AE3251 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MADESPKSIY DFTVKDIGGN DVSLDQYKGK TLLVVNVASK CGLTDANYKE LNVLYEKYKE 

        70         80         90        100        110        120 
QGLEILAFPC NQFLGQEPGN NEEIQQTVCT RFKAEFPIFD KVDVNGKNTA PLYKYLKAEK 

       130        140        150        160 
GGLLIDAIKW NFTKFLVSPD GKVLQRYSPR TSPLQFEKDI QTALGQASS 

O04922 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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