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UniProtKB/Swiss-Prot entry O04104

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name URIC2_SOYBN
Primary accession number O04104
Secondary accession numbers None
Integrated into Swiss-Prot on July 15, 1999
Sequence was last modified on July 1, 1997 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 53)
Name and origin of the protein
Protein name Uricase-2 isozyme 2
Synonyms EC 1.7.3.3
Uricase II isozyme 2
Urate oxidase
Nodulin 35
N-35
Non-symbiotic uricase
Gene name None
From
Glycine max (Soybean) [TaxID: 3847] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids I; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine.
Protein existence 1: Evidence at protein level;
References
[1]
 NUCLEOTIDE SEQUENCE, AND PROTEIN SEQUENCE OF 245-262.
STRAIN=cv. Dare;
PubMed=16593585 [NCBI, ExPASy, EBI, Israel, Japan]
Nguyen T., Zelechowska M., Foster V., Bergmann H., Verma D.P.S.;
"Primary structure of the soybean nodulin-35 gene encoding uricase II localized in the peroxisome of uninfected cells of nodules.";
Proc. Natl. Acad. Sci. U.S.A. 82:5040-5044(1985).
[2]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
STRAIN=cv. Akisengoku;
TISSUE=Root nodule;
PubMed=9245835 [NCBI, ExPASy, EBI, Israel, Japan]
Takane K., Tajima S., Kouchi H.;
"Two distinct uricase II (nodulin 35) genes are differentially expressed in soybean plants.";
Mol. Plant Microbe Interact. 10:735-741(1997).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
M10594; AAA33994.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AB002807; BAA19670.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AB002809; BAA19672.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
UniGene Gma.29861
3D structure databases
HSSP Q00511; 1UOX. [HSSP ENTRY / PDB]
ModBase O04104.
Ontologies
GO
GO:0005777; Cellular component: peroxisome (inferred from electronic annotation from UniProtKB-KW).
GO:0004846; Molecular function: urate oxidase activity (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0006144; Biological process: purine base metabolic process (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR002042; Uricase.
Graphical view of domain structure.
Gene3D G3DSA:3.10.270.10; Uricase; 1.
PANTHER PTHR10395:SF1; Uricase; 1.
Pfam PF01014; Uricase; 2.
Pfam graphical view of domain structure.
PRINTS PR00093; URICASE.
ProDom PD003367; Uricase; 2.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR03383; urate_oxi; 1.
PROSITE PS00366; URICASE; 1.
Other
ProtoNet O04104.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Direct protein sequencing; Oxidoreductase; Peroxisome; Purine metabolism.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   309  309     Uricase-2 isozyme 2. PRO_0000166004
ACT_SITE   183   183        Charge relay system (By similarity). 
ACT_SITE   239   239        Charge relay system (By similarity). 
CONFLICT   208   208        L -> F (in Ref. 1; AAA33994). 
Sequence information
Length: 309 AA [This is the length of the unprocessed precursor] Molecular weight: 35137 Da [This is the MW of the unprocessed precursor] CRC64: 81B8F8F7ACAA00A9 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MAQQEVVEGF KFEQRHGKER VRVARVWKTR QGQHFVVEWR VGITLFSDCV NSYLRDDNSD 

        70         80         90        100        110        120 
IVATDTMKNT VYAKAKECSD ILSAEDFAIL LAKHFVSFYK KVTGAIVNIV EKPWERVIVD 

       130        140        150        160        170        180 
GQPHEHGFKL GSEKHTTEAI VQKSGSLQLT SGIEGLSVLK TTQSGFVNFI RDKYTALPDT 

       190        200        210        220        230        240 
RERILATEVT ALWRYSYESQ YSLPQKPLYF TEKYQEVKKV LADTFFGPPN GGVYSPSVQN 

       250        260        270        280        290        300 
TLYLMAKATL NRFPDIAYVS LKMPNLHFLP VNISNKDGPI VKFEDDVYLP TDEPHGSIQA 


SLSRLWSKL
O04104 in FASTA format

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