[1]	NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1). TISSUE=Flower; DOI=10.1007/BF00019114; PubMed=7579155 [NCBI, ExPASy, EBI, Israel, Japan] Kang H.-G., Noh Y.-S., Chung Y.-Y., Costa M.A., An K., An G.; "Phenotypic alterations of petal and sepal by ectopic expression of a rice MADS box gene in tobacco."; Plant Mol. Biol. 29:1-10(1995).
[2]	NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2). Yao Q., Peng R., Xiong A.; "Molecular and phylogenetic analyses of the complete MADS-box transcription factor family in rice."; Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
[3]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. STRAIN=cv. Nipponbare; DOI=10.1038/nature01184; PubMed=12447438 [NCBI, ExPASy, EBI, Israel, Japan] Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y., Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H., Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M., Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.; "The genome sequence and structure of rice chromosome 1."; Nature 420:312-316(2002).
[4]	NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3). STRAIN=cv. Nipponbare; DOI=10.1126/science.1081288; PubMed=12869764 [NCBI, ExPASy, EBI, Israel, Japan] The rice full-length cDNA consortium; "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."; Science 301:376-379(2003).
[5]	FUNCTION. DOI=10.1023/A:1006051911291; PubMed=9869408 [NCBI, ExPASy, EBI, Israel, Japan] Kang H.-G., Jeon J.-S., Lee S., An G.; "Identification of class B and class C floral organ identity genes from rice plants."; Plant Mol. Biol. 38:1021-1029(1998).
[6]	TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE. PubMed=10945340 [NCBI, ExPASy, EBI, Israel, Japan] Kyozuka J., Kobayashi T., Morita M., Shimamoto K.; "Spatially and temporally regulated expression of rice MADS box genes with similarity to Arabidopsis class A, B and C genes."; Plant Cell Physiol. 41:710-718(2000).
[7]	FUNCTION. DOI=10.1093/pcp/pcf010; PubMed=11828031 [NCBI, ExPASy, EBI, Israel, Japan] Kyozuka J., Shimamoto K.; "Ectopic expression of OsMADS3, a rice ortholog of AGAMOUS, caused a homeotic transformation of lodicules to stamens in transgenic rice plants."; Plant Cell Physiol. 43:130-135(2002).
[8]	FUNCTION, AND DEVELOPMENTAL STAGE. DOI=10.1105/tpc.105.037200; PubMed=16326928 [NCBI, ExPASy, EBI, Israel, Japan] Yamaguchi T., Lee D.-Y., Miyao A., Hirochika H., An G., Hirano H.; "Functional diversification of the two C-class MADS box genes OSMADS3 and OSMADS58 in Oryza sativa."; Plant Cell 18:15-28(2006).

Comments

FUNCTION: Probable transcription factor involved in the development of floral organs. Acts as C-class protein in association with MADS58. Involved in the control of lodicule number (whorl 2), stamen specification (whorl 3) and floral meristem determinacy (whorl 4), but not in the regulation of carpel morphogenesis. Plays a more predominant role in controlling lodicule development and in specifying stamen identity than MADS58.
SUBCELLULAR LOCATION: Nucleus (Probable).

ALTERNATIVE PRODUCTS: 3 named isoforms [FASTA] produced by alternative splicing.

Name	1
Isoform ID	Q40704-1
This is the isoform sequence displayed in this entry.

Name	2
Isoform ID	Q40704-2
Note: No experimental confirmation available.
Features which should be applied to build the isoform sequence: VSP_017779.

Name	3
Isoform ID	Q40704-3
Note: No experimental confirmation available.
Features which should be applied to build the isoform sequence: VSP_017777, VSP_017778.

TISSUE SPECIFICITY: Expressed in lemmas, paleas and lodicules.
DEVELOPMENTAL STAGE: Expressed at early stage of flower development in stamen anlagen before stamen initiation, and at later stage in lodicule and ovule primordia initiation region.
MISCELLANEOUS: Plants lacking MADS3 show homeotic transformation of stamens into lodicules, and ectopic development of lodicules where they do not form in the wild-type. The transformation of lodicules into stamens is observed in overexpressing plants.
SIMILARITY: Contains 1 K-box domain.
SIMILARITY: Contains 1 MADS-box domain.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

L37528; AAA99964.1; -; mRNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
AY553724; AAS60204.1; -; mRNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
AP003105; -; NOT_ANNOTATED_CDS; Genomic_DNA.	[EMBL / GenBank / DDBJ]
AK108568; -; NOT_ANNOTATED_CDS; mRNA.	[EMBL / GenBank / DDBJ]

PIR

S59480; S59480.

3D structure databases

HSSP

Q02078; 1EGW. [HSSP ENTRY / PDB]

ModBase

Q40704.

Protein-protein interaction databases

IntAct

Q40704; 3.

Organism-specific databases

Gramene

Q40704; -.

Ontologies

GO:0005634;	Cellular component: nucleus (inferred from electronic annotation from InterPro).
GO:0043565;	Molecular function: sequence-specific DNA binding (inferred from electronic annotation from InterPro).
GO:0003700;	Molecular function: transcription factor activity (inferred from electronic annotation from InterPro).
GO:0030154;	Biological process: cell differentiation (inferred from electronic annotation from UniProtKB-KW).
GO:0009908;	Biological process: flower development (inferred from electronic annotation from UniProtKB-KW).
GO:0006355;	Biological process: regulation of transcription, DNA-dependent (inferred from electronic annotation from InterPro).
QuickGo view.

Family and domain databases

InterPro

IPR002487; TF_Kbox.
IPR002100; TF_MADSbox.
Graphical view of domain structure.

Pfam

PF01486; K-box; 1.
PF00319; SRF-TF; 1.
Pfam graphical view of domain structure.

PRINTS

PR00404; MADSDOMAIN.

SMART

SM00432; MADS; 1.
SMART graphical view of domain structure.

PROSITE

PS51297; K_BOX; 1.
PS00350; MADS_BOX_1; 1.
PS50066; MADS_BOX_2; 1.
PROSITE graphical view of domain structure (profiles).

Other

ProtoNet

Q40704.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Activator; Alternative splicing; Developmental protein; Differentiation; DNA-binding; Flowering; Nucleus; Transcription; Transcription regulation.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 236`	`236`	`MADS-box transcription factor 3.`	`PRO_0000229893`
`DOMAIN`	`1 61`	`61`	`MADS-box.`
`DOMAIN`	`87 178`	`92`	`K-box.`
`VAR_SEQ`	`110 114`		`RTIVG -> LTRLA (in isoform 3).`	`VSP_017777`
`VAR_SEQ`	`115 236`		`Missing (in isoform 3).`	`VSP_017778`
`VAR_SEQ`	`231 236`		`QQPAFN -> SRPSISFGVDTVRTHVR (in isoform 2).`	`VSP_017779`

Sequence information

Length: 236 AA [This is the length of the unprocessed precursor]

Molecular weight: 27141 Da [This is the MW of the unprocessed precursor]

CRC64: 241BD9BCE2DAD35F [This is a checksum on the sequence]

        10         20         30         40         50         60 
MGRGKIEIKR IENTTNRQVT FCKRRNGLLK KAYELSVLCD AEVALIVFSS RGRLYEYANN 

        70         80         90        100        110        120 
SVKSTVERYK KANSDTSNSG TVAEVNAQHY QQESSKLRQQ ISSLQNANSR TIVGDSINTM 

       130        140        150        160        170        180 
SLRDLKQVEN RLEKGIAKIR ARKNELLYAE VEYMQKREVE LQNDNMYLRS KVVENERGQQ 

       190        200        210        220        230 
PLNMMGAAST SEYDHMVNNP YDSRNFLQVN IMQQPQHYAH QLQPTTLQLG QQPAFN

Q40704 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools