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UniProtKB/Swiss-Prot entry Q96524


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CRY2_ARATH
Primary accession number Q96524
Secondary accession numbers B0LQ23 B0LQ24 B0LQ25 B0LQ29 Q42549 Q42603 Q42604 Q56ZL8 Q696X6 Q696X8 Q696Z7 Q697A2 Q8VWL9 Q8VZY9
Integrated into Swiss-Prot on December 15, 1998
Sequence was last modified on December 15, 1998 (Sequence version 2)
Annotations were last modified on    December 16, 2008 (Entry version 78)
Name and origin of the protein
Protein name Cryptochrome-2
Synonym Blue light photoreceptor
Gene name
Name: CRY2
Synonyms: PHH1
OrderedLocusNames: At1g04400
ORFNames: F19P19.14
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
STRAIN=cv. Columbia;
DOI=10.1007/s004380050321; PubMed=9003312 [NCBI, ExPASy, EBI, Israel, Japan]
Hoffman P.D., Batschauer A., Hays J.B.;
"PHH1, a novel gene from Arabidopsis thaliana that encodes a protein similar to plant blue-light photoreceptors and microbial photolyases.";
Mol. Gen. Genet. 253:259-265(1996).
[2]
NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=cv. Columbia;
Lin C., Ahmad M., Chan J., Cashmore A.R.;
"CRY2: a second member of the Arabidopsis cryptochrome gene family.";
(er) Plant Gene Register PGR96-001.
[3]
NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
STRAIN=cv. Cvi-0, and cv. Landsberg erecta;
DOI=10.1038/ng767; PubMed=11726930 [NCBI, ExPASy, EBI, Israel, Japan]
El-Din El-Assal S., Alonso-Blanco C., Peeters A.J.M., Raz V., Koornneef M.;
"A QTL for flowering time in Arabidopsis reveals a novel allele of CRY2.";
Nat. Genet. 29:435-440(2001).
[4]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=cv. Bla-10, cv. Bsch-0, cv. Bu-0, cv. Bu-2, cv. Chi-1, cv. Co-1, cv. Columbia, cv. Cvi-0, cv. Da(1)-12, cv. Di-G, cv. El-0, cv. Fe-1, cv. Gr-3, cv. Hn-0, cv. Kon, cv. Kr-0, cv. Landsberg erecta, cv. Le-0, cv. Li-3, cv. Lip-0, cv. Lz-0, cv. Mrk-0, cv. Mt-0, cv. Mz-0, cv. Ove-0, cv. PHW-1, cv. PHW-32, cv. PHW-36, cv. Sha, cv. Stw-0, cv. Ta-0, and cv. Wassilewskija-3;
DOI=10.1007/s00239-007-9063-3; PubMed=18273534 [NCBI, ExPASy, EBI, Israel, Japan]
Moore R.C., Stevens M.H.;
"Local patterns of nucleotide polymorphism are highly variable in the selfing species Arabidopsis thaliana.";
J. Mol. Evol. 66:116-129(2008).
[5]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/35048500; PubMed=11130712 [NCBI, ExPASy, EBI, Israel, Japan]
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.;
"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
Nature 408:816-820(2000).
[6]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
DOI=10.1126/science.1088305; PubMed=14593172 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis genome.";
Science 302:842-846(2003).
[7]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 2-612.
STRAIN=cv. Bla-10, cv. Bsch-0, cv. Bu-0, cv. Bu-2, cv. Chi-1, cv. Co-1, cv. Cvi-0, cv. Da(1)-12, cv. Di-G, cv. El-0, cv. Fe-1, cv. Gr-3, cv. Hn-0, cv. Kon, cv. Kr-0, cv. Landsberg erecta, cv. Le-0, cv. Li-3, cv. Lip-0, cv. Lz-0, cv. Mrk-0, cv. Mt-0, cv. Mz-0, cv. Ove-0, cv. Oy-1, cv. PHW-1, cv. PHW-33, cv. PHW-36, cv. Sha, cv. Stw-0, and cv. Ta-0;
DOI=10.1534/genetics.103.024950; PubMed=15280248 [NCBI, ExPASy, EBI, Israel, Japan]
Olsen K.M., Halldorsdottir S.S., Stinchcombe J.R., Weinig C., Schmitt J., Purugganan M.D.;
"Linkage disequilibrium mapping of Arabidopsis CRY2 flowering time alleles.";
Genetics 167:1361-1369(2004).
[8]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 485-612.
STRAIN=cv. Columbia;
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K., Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.;
"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
[9]
FUNCTION, AND MUTAGENESIS OF GLY-337.
DOI=10.1038/33701; PubMed=9565033 [NCBI, ExPASy, EBI, Israel, Japan]
Ahmad M., Jarillo J.A., Smirnova O., Cashmore A.R.;
"Cryptochrome blue-light photoreceptors of Arabidopsis implicated in phototropism.";
Nature 392:720-723(1998).
[10]
PHOSPHORYLATION.
DOI=10.1016/S1097-2765(00)80094-5; PubMed=9651577 [NCBI, ExPASy, EBI, Israel, Japan]
Ahmad M., Jarillo J.A., Smirnova O., Cashmore A.R.;
"The CRY1 blue light photoreceptor of Arabidopsis interacts with phytochrome A in vitro.";
Mol. Cell 1:939-948(1998).
[11]
FUNCTION.
DOI=10.1073/pnas.95.5.2686; PubMed=9482948 [NCBI, ExPASy, EBI, Israel, Japan]
Lin C., Yang H., Guo H., Mockler T., Chen J., Cashmore A.R.;
"Enhancement of blue-light sensitivity of Arabidopsis seedlings by a blue light receptor cryptochrome 2.";
Proc. Natl. Acad. Sci. U.S.A. 95:2686-2690(1998).
[12]
SUBCELLULAR LOCATION.
PubMed=10476076 [NCBI, ExPASy, EBI, Israel, Japan]
Kleiner O., Kircher S., Harter K., Batschauer A.;
"Nuclear localization of the Arabidopsis blue light receptor cryptochrome 2.";
Plant J. 19:289-296(1999).
[13]
INTERACTION WITH PHYB.
DOI=10.1038/35041583; PubMed=11089975 [NCBI, ExPASy, EBI, Israel, Japan]
Mas P., Devlin P.F., Panda S., Kay S.A.;
"Functional interaction of phytochrome B and cryptochrome 2.";
Nature 408:207-211(2000).
[14]
INTERACTION WITH COP1.
DOI=10.1126/science.1063630; PubMed=11509693 [NCBI, ExPASy, EBI, Israel, Japan]
Wang H., Ma L.-G., Li J.-M., Zhao H.-Y., Deng X.W.;
"Direct interaction of Arabidopsis cryptochromes with COP1 in light control development.";
Science 294:154-158(2001).
[15]
PHOSPHORYLATION.
DOI=10.1038/nature00815; PubMed=12066190 [NCBI, ExPASy, EBI, Israel, Japan]
Shalitin D., Yang H., Mockler T.C., Maymon M., Guo H., Whitelam G.C., Lin C.;
"Regulation of Arabidopsis cryptochrome 2 by blue-light-dependent phosphorylation.";
Nature 417:763-767(2002).
[16]
FUNCTION.
DOI=10.1104/pp.103.029819; PubMed=14605222 [NCBI, ExPASy, EBI, Israel, Japan]
El-Din El-Assal S., Alonso-Blanco C., Peeters A.J., Wagemaker C., Weller J.L., Koornneef M.;
"The role of cryptochrome 2 in flowering in Arabidopsis.";
Plant Physiol. 133:1504-1516(2003).
[17]
INDUCTION.
DOI=10.1073/pnas.0437826100; PubMed=12578985 [NCBI, ExPASy, EBI, Israel, Japan]
Mockler T., Yang H., Yu X., Parikh D., Cheng Y.C., Dolan S., Lin C.;
"Regulation of photoperiodic flowering by Arabidopsis photoreceptors.";
Proc. Natl. Acad. Sci. U.S.A. 100:2140-2145(2003).
[18]
FUNCTION.
DOI=10.1073/pnas.0501011102; PubMed=16093319 [NCBI, ExPASy, EBI, Israel, Japan]
Mao J., Zhang Y.C., Sang Y., Li Q.H., Yang H.Q.;
"A role for Arabidopsis cryptochromes and COP1 in the regulation of stomatal opening.";
Proc. Natl. Acad. Sci. U.S.A. 102:12270-12275(2005).
[19]
FUNCTION.
DOI=10.1007/s00425-006-0280-6; PubMed=16703358 [NCBI, ExPASy, EBI, Israel, Japan]
Canamero R.C., Bakrim N., Bouly J.-P., Garay A., Dudkin E.E., Habricot Y., Ahmad M.;
"Cryptochrome photoreceptors cry1 and cry2 antagonistically regulate primary root elongation in Arabidopsis thaliana.";
Planta 224:995-1003(2006).
[20]
COFACTOR.
DOI=10.1074/jbc.M700616200; PubMed=17355959 [NCBI, ExPASy, EBI, Israel, Japan]
Banerjee R., Schleicher E., Meier S., Viana R.M., Pokorny R., Ahmad M., Bittl R., Batschauer A.;
"The signaling state of Arabidopsis cryptochrome 2 contains flavin semiquinone.";
J. Biol. Chem. 282:14916-14922(2007).
[21]
FUNCTION.
DOI=10.1111/j.1365-313X.2007.03093.x; PubMed=17470059 [NCBI, ExPASy, EBI, Israel, Japan]
Tessadori F., Schulkes R.K., van Driel R., Fransz P.;
"Light-regulated large-scale reorganization of chromatin during the floral transition in Arabidopsis.";
Plant J. 50:848-857(2007).
[22]
SUBCELLULAR LOCATION, SUBUNIT, AND PHOSPHORYLATION.
DOI=10.1073/pnas.0701912104; PubMed=17438275 [NCBI, ExPASy, EBI, Israel, Japan]
Yu X., Shalitin D., Liu X., Maymon M., Klejnot J., Yang H., Lopez J., Zhao X., Bendehakkalu K.T., Lin C.;
"Derepression of the NC80 motif is critical for the photoactivation of Arabidopsis CRY2.";
Proc. Natl. Acad. Sci. U.S.A. 104:7289-7294(2007).
[23]
SUBCELLULAR LOCATION, UBIQUITINATION, AND PHOSPHORYLATION.
DOI=10.1105/tpc.107.053017; PubMed=17965271 [NCBI, ExPASy, EBI, Israel, Japan]
Yu X., Klejnot J., Zhao X., Shalitin D., Maymon M., Yang H., Lee J., Liu X., Lopez J., Lin C.;
"Arabidopsis cryptochrome 2 completes its posttranslational life cycle in the nucleus.";
Plant Cell 19:3146-3156(2007).
[24]
FUNCTION.
DOI=10.1105/tpc.106.048157; PubMed=17259260 [NCBI, ExPASy, EBI, Israel, Japan]
Endo M., Mochizuki N., Suzuki T., Nagatani A.;
"CRYPTOCHROME2 in vascular bundles regulates flowering in Arabidopsis.";
Plant Cell 19:84-93(2007).
Comments
  • FUNCTION: Mediates blue light-induced gene expression. Involved in blue light-dependent stomatal opening and inhibition of stem and root growth. Regulates the timing of flowering by promoting the expression of 'FLOWERING LOCUS T' (FT) in vascular bundles. Negatively regulated by 'FLOWERING LOCUS C' (FLC). Involved in triggering chromatin decondensation.
  • COFACTOR: Binds 1 FAD per subunit.
  • COFACTOR: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit (By similarity).
  • SUBUNIT: Homodimer. Interacts with COP1 and PHYB.
  • INTERACTION:
    Self; NbExp=1; IntAct=EBI-531555, EBI-531555;
    P14713:PHYB; NbExp=2; IntAct=EBI-531555, EBI-300727;
  • SUBCELLULAR LOCATION: Nucleus.
  • INDUCTION: Daily oscillation of protein abundance in plants grown in short days (SD) but not in long days (LD).
  • DOMAIN: The NC80 domain (486-565) contains a major active site responsible for the signal transduction processes regulating both hypocotyl inhibition and floral promotion. The C-terminal tail (564-612) is not required for physiological activity of the protein.
  • PTM: Phosphorylated; in response to blue light. Required for degradation.
  • PTM: Ubiquitinated.
  • MISCELLANEOUS: Plants lacking CRY2 show increased root elongation in blue light.
  • MISCELLANEOUS: Phosphorylation of the C-terminal tail and resulting derepression of NC80 domain may both depend on homodimerization.
  • SIMILARITY: Belongs to the DNA photolyase class-1 family.
  • SIMILARITY: Contains 1 DNA photolyase domain.
  • CAUTION: Was originally (PubMed:9003312) thought to be a DNA photolyase.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U62549; AAB04996.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
U62550; AAB04997.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
X99061; CAA67508.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
U43397; AAD09837.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY057440; AAL16377.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY057441; AAL16378.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY057442; AAL16379.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351967; ABY77601.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351968; ABY77602.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351969; ABY77603.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351970; ABY77604.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351971; ABY77605.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351972; ABY77606.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351973; ABY77607.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351974; ABY77608.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351975; ABY77609.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351976; ABY77610.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351977; ABY77611.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351978; ABY77612.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351979; ABY77613.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351980; ABY77614.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351981; ABY77615.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351982; ABY77616.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351983; ABY77617.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351984; ABY77618.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351985; ABY77619.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351986; ABY77620.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351987; ABY77621.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351988; ABY77622.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351989; ABY77623.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351990; ABY77624.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351991; ABY77625.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351993; ABY77627.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351992; ABY77626.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351994; ABY77628.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351995; ABY77629.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351996; ABY77630.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351997; ABY77631.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
EU351998; ABY77632.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AC000104; AAB70435.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BT008576; AAP40403.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BT008648; AAP40463.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576241; AAT80593.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576242; AAT80594.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576243; AAT80595.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576244; AAT80596.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576245; AAT80597.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576246; AAT80598.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576247; AAT80599.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576248; AAT80600.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576249; AAT80601.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576250; AAT80602.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576251; AAT80603.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576252; AAT80604.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576253; AAT80605.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576254; AAT80606.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576255; AAT80607.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576256; AAT80608.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576257; AAT80609.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576258; AAT80610.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576259; AAT80611.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576260; AAT80612.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576261; AAT80613.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576262; AAT80614.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576263; AAT80615.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576264; AAT80616.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576265; AAT80617.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576266; AAT80618.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576267; AAT80619.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576268; AAT80620.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576269; AAT80621.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576270; AAT80622.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY576271; AAT80623.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AK220946; BAD94467.1; ALT_INIT; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR A86176; A86176.
S71221; S71221.
RefSeq NP_171935.1; -.
NP_849588.1; -.
UniGene At.21976
3D structure databases
HSSP P37250; 1IQR. [HSSP ENTRY / PDB]
ModBase Q96524.
Protein-protein interaction databases
IntAct Q96524; 2.
Organism-specific databases
TAIR At1g04400; -.
Gene expression databases
ArrayExpress Q96524; -.
GermOnline AT1G04400; Arabidopsis thaliana.
Ontologies
GO
GO:0005634; Cellular component: nucleus (inferred from electronic annotation from UniProtKB-KW).
GO:0005773; Cellular component: vacuole (inferred from direct assay from TAIR).
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from UniProtKB-KW).
GO:0003913; Molecular function: DNA photolyase activity (inferred from electronic annotation from InterPro).
GO:0009881; Molecular function: photoreceptor activity (inferred from electronic annotation from UniProtKB-KW).
GO:0042803; Molecular function: protein homodimerization activity (inferred from physical interaction from TAIR).
GO:0006338; Biological process: chromatin remodeling (inferred from mutant phenotype from TAIR).
GO:0010617; Biological process: circadian regulation of calcium ion oscillation (inferred from mutant phenotype from TAIR).
GO:0006281; Biological process: DNA repair (inferred from electronic annotation from InterPro).
GO:0009638; Biological process: phototropism (inferred from genetic interaction from TAIR).
GO:0009911; Biological process: positive regulation of flower development (inferred from mutant phenotype from TAIR).
GO:0018298; Biological process: protein-chromophore linkage (inferred from electronic annotation from UniProtKB-KW).
GO:0009414; Biological process: response to water deprivation (inferred from genetic interaction from TAIR).
GO:0010118; Biological process: stomatal movement (inferred from genetic interaction from TAIR).
QuickGo view.
Family and domain databases
InterPro IPR002081; Cryptochrome/DNA_photolyase_1.
IPR014134; Cryptochrome_pln.
IPR006050; DNA_photolyase_N.
IPR005101; Photolyase_FAD-bd/Cryptochr_C.
IPR014729; Rossmann-like_a/b/a_fold.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.620; Rossmann-like_a/b/a_fold; 1.
Pfam PF00875; DNA_photolyase; 1.
PF03441; FAD_binding_7; 1.
Pfam graphical view of domain structure.
PRINTS PR00147; DNAPHOTLYASE.
ProDom PD004390; FAD_binding_N; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR02766; crypt_chrom_pln; 1.
PROSITE PS00394; DNA_PHOTOLYASES_1_1; 1.
PS00691; DNA_PHOTOLYASES_1_2; 1.
Proteomics databases
PRIDE Q96524; -.
Genome annotation databases
GeneID 839529; -.
GenomeReviews CT485782_GR; AT1G04400.
KEGG ath:AT1G04400; -.
NMPDR fig|3702.1.peg.585; -.
Other
ProtoNet Q96524.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Chromophore; Complete proteome; FAD; Flavoprotein; Nucleotide-binding; Nucleus; Phosphoprotein; Photoreceptor protein; Receptor; Sensory transduction; Ubl conjugation.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   612  612     Cryptochrome-2. PRO_0000085122
DOMAIN   5   175  171     DNA photolyase. 
NP_BIND   244   248  5     FAD (By similarity). 
COMPBIAS   22    27  6     Poly-Ala. 
COMPBIAS   546   550  5     Poly-Glu. 
COMPBIAS   566   587  22     Ser-rich. 
BINDING   232   232        FAD (By similarity). 
BINDING   357   357        ATP (By similarity). 
BINDING   387   387        FAD; via carbonyl oxygen (By similarity).