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UniProtKB/Swiss-Prot entry B0CQN7


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NCB5R_LACBS
Primary accession number B0CQN7
Secondary accession numbers None
Integrated into Swiss-Prot on April 29, 2008
Sequence was last modified on February 26, 2008 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 10)
Name and origin of the protein
Protein name NADH-cytochrome b5 reductase 1
Synonyms EC 1.6.2.2
Microsomal cytochrome b reductase
Gene name
Name: MCR1.1
ORFNames: LACBIDRAFT_300832
From
Laccaria bicolor (strain S238N-H82) (Bicoloured deceiver) (Laccaria laccata var. bicolor) [TaxID: 486041] 
Taxonomy Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes; Agaricomycetidae; Agaricales; Tricholomataceae; Laccaria.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/nature06556; PubMed=18322534 [NCBI, ExPASy, EBI, Israel, Japan]
Martin F., Aerts A., Ahren D., Brun A., Danchin E.G.J., Duchaussoy F., Gibon J., Kohler A., Lindquist E., Pereda V., Salamov A., Shapiro H.J., Wuyts J., Blaudez D., Buee M., Brokstein P., Canbaeck B., Cohen D., Courty P.E., Coutinho P.M., Delaruelle C., Detter J.C., Deveau A., DiFazio S., Duplessis S., Fraissinet-Tachet L., Lucic E., Frey-Klett P., Fourrey C., Feussner I., Gay G., Grimwood J., Hoegger P.J., Jain P., Kilaru S., Labbe J., Lin Y.C., Legue V., Le Tacon F., Marmeisse R., Melayah D., Montanini B., Muratet M., Nehls U., Niculita-Hirzel H., Oudot-Le Secq M.P., Peter M., Quesneville H., Rajashekar B., Reich M., Rouhier N., Schmutz J., Yin T., Chalot M., Henrissat B., Kuees U., Lucas S., Van de Peer Y., Podila G.K., Polle A., Pukkila P.J., Richardson P.M., Rouze P., Sanders I.R., Stajich J.E., Tunlid A., Tuskan G., Grigoriev I.V.;
"The genome of Laccaria bicolor provides insights into mycorrhizal symbiosis.";
Nature 452:88-92(2008).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
DS547091; EDR15673.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_001873881.1; -.
3D structure databases
ModBase B0CQN7.
Ontologies
GO
GO:0005789; Cellular component: endoplasmic reticulum membrane (inferred from electronic annotation from UniProtKB-SubCell).
GO:0016021; Cellular component: integral to membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0005741; Cellular component: mitochondrial outer membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0004128; Molecular function: cytochrome-b5 reductase activity (inferred from electronic annotation from EC).
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR001834; Cyt_B5_reductase.
IPR001709; FPN_cyt_redctse.
IPR008333; OxRdtase_FAD-bd.
IPR001433; OxRdtase_FAD/NAD_bd.
Graphical view of domain structure.
Pfam PF00970; FAD_binding_6; 1.
PF00175; NAD_binding_1; 1.
Pfam graphical view of domain structure.
PRINTS PR00406; CYTB5RDTASE.
PR00371; FPNCR.
PROSITE PS51384; FAD_FR; 1.
PROSITE graphical view of domain structure (profiles).
Genome annotation databases
GeneID 6069923; -.
KEGG lbc:LACBIDRAFT_300832; -.
Other
ProtoNet B0CQN7.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Endoplasmic reticulum; FAD; Flavoprotein; Membrane; Mitochondrion; Mitochondrion outer membrane; NAD; Oxidoreductase; Transmembrane.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   308  308     NADH-cytochrome b5 reductase 1. PRO_0000330155
TRANSMEM   29    49  21     Potential. 
DOMAIN   64   167  104     FAD-binding FR-type. 
NP_BIND   147   162  16     FAD (By similarity). 
NP_BIND   173   205  33     FAD (By similarity). 
Sequence information
Length: 308 AA [This is the length of the unprocessed precursor] Molecular weight: 33656 Da [This is the MW of the unprocessed precursor] CRC64: 22FB3E946AF9C4E6 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSGRVEVENI PGQVANLLKN VTAGDLLNVA SSPAFLVAAA AIVIAAAFYS KVFNSTRPKP 

        70         80         90        100        110        120 
LDPSIWKEFP LQKKNQVSPN TAIYTFKLPH AEDVLGLPIG QHISVSADIN GKNIVRSYTP 

       130        140        150        160        170        180 
ISRQNARGRF ELIIKTYEKG NISRHVASLK IGDTLRVKGP KGNFKYTPGL TAHLGMIAGG 

       190        200        210        220        230        240 
TGLAPMIQIV RAILQNPPDR TNITLIYANV NEEDILLRAE LDALAMGYES RFNLFYVLNN 

       250        260        270        280        290        300 
PPSGWTGGVG FVTKEHIKDL LPNPNESNSK ILICGPPPMV TAMKKNLEEI KYPVPNTISK 


LDDKVFVF 

B0CQN7 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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NPSA logo NPSA Sequence analysis tools

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